Irritable Bowel Syndrome Diarrhea Predominant
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Study to Assess Effects of Postbiotic vs Placebo in Participants With Diarrhea-predominant IBS [NA]
Completed clinical trial comparing a postbiotic to placebo in participants with diarrhea-predominant irritable bowel syndrome.
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: A Flexible Clinical Trial to Test if Freeze-dried Fecal Microbiota Therapy Helps Treat Diarrhea-predominant Irritable Bowel Syndrome or Prevent Recurring C. Difficile Infections. [Phase 2]
A Phase 2 clinical trial is exploring whether a freeze-dried fecal microbiota therapy can treat diarrhea-predominant irritable bowel syndrom…
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: Phase II Clinical Trial of OPS-2071 in the Treatment of Irritable Bowel Syndrome of Diarrhea Type [Phase 2]
Phase II trial of OPS-2071 for Irritable Bowel Syndrome with diarrhea type (IBS-D) has completed. The update does not report trial results.
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CLINICAL_TRIALS research · 2024-12-31Clinical Trial Update: Efficacy and Safety of Changkang Granules in the Treatment of Irritable Bowel Syndrome With Predominant Diarrhea (Liver qi Affecting the Spleen Pattern) [Phase 3]
Phase 3 clinical trial update evaluating the efficacy and safety of Changkang Granules for diarrhea-predominant irritable bowel syndrome, wi…
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CLINICAL_TRIALS trial_result · 2019-06-06Clinical Trial Update: A Phase 2 Pilot Study to Assess ASP7147 in Patients With Diarrhea Predominant Irritable Bowel Syndrome (IBS-D) [Phase 2]
Phase 2 pilot study evaluating ASP7147 in patients with diarrhea-predominant irritable bowel syndrome has completed.
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FDA approval · 2019-04-03FDA Approved: LOTRONEX — Supplemental Application (Legacy Pharma USA Inc.)
FDA approved a supplemental application for Lotronex (alosetron hydrochloride) by Legacy Pharma USA Inc., approving a supplemental submissio…
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: Proposal Evaluating Time-specific Relationships Between Variables of Pain, Stress, and Bloating in IBS Diarrhea and Constipation Symptoms Using a Palm Pilot
This clinical trial update reports the completion of a study evaluating time-specific relationships between pain, stress, and bloating in ir…
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CLINICAL_TRIALS trial_result · 2017-05-01Clinical Trial Update: Safety and Efficacy Study of GR68755 (Alosetron Hydrochloride) to Treat Severe Diarrhea-Predominant Irritable Bowel Syndrome (IBS) [Phase 2]
Phase 2 safety and efficacy study of GR68755 (alosetron hydrochloride) for severe diarrhea-predominant irritable bowel syndrome has complete…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Effects of Butyrate on Colonic Health of Patients With Diarrhoea Predominant IBS and UC in Remission [NA]
This completed clinical trial from Maastricht University Medical Center assessed the effects of butyrate on colonic health in patients with …
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: A Phase 2, Multi-center Study to Evaluate the Efficacy and Safety of ONO-2952 in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) [Phase 2]
A completed Phase 2 multi-center study evaluating the efficacy and safety of ONO-2952 in female subjects with diarrhea-predominant irritable…
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CLINICAL_TRIALS research · 2016-01-27Clinical Trial Update: Ability of Mayo Clinic High-performance Liquid Chromatography (HPLC) Method to Measure Fecal Bile Acids [Phase 4]
A Mayo Clinic Phase 4 clinical trial evaluated the ability of a high-performance liquid chromatography method to measure fecal bile acids in…
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CLINICAL_TRIALS trial_result · 2015-07-29Clinical Trial Update: Use of SBI in IBS Subjects Following a Successful Treatment of Small Intestinal Bacterial Overgrowth [NA]
Clinical trial update announcing completion of a study evaluating SBI in patients with diarrhea-predominant irritable bowel syndrome followi…
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CLINICAL_TRIALS trial_result · 2015-04-10Clinical Trial Update: Acupuncture for Patients With Diarrhea-predominant IBS or Functional Diarrhea: a Randomized Controlled Trial [Phase 2, Phase 3]
Clinical trial evaluating acupuncture for diarrhea-predominant irritable bowel syndrome and functional diarrhea has completed Phase 2 and Ph…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: A Study to Evaluate Efficacy of Ramosetron on Diarrhea-predominant Irritable Bowel Syndrome (IBS) in Male Patients [Phase 4]
This Phase 4 clinical trial completed evaluating the efficacy of Ramosetron in male patients with diarrhea-predominant irritable bowel syndr…
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CLINICAL_TRIALS trial_result · 2013-06-18Clinical Trial Update: The Effects of Multi-strain Probiotics in Adults With Diarrhea Predominant Irritable Bowel Syndrome [NA]
A clinical trial update examining the effects of a multi-strain probiotic formulation in adults with diarrhea-predominant irritable bowel sy…
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CLINICAL_TRIALS trial_result · 2012-07-11Clinical Trial Update: Changes in Gastrointestinal Microbiota Using VSL#3 in Patients With IBS-D [Phase 4]
This clinical trial update describes changes in the gastrointestinal microbiota of IBS patients treated with the probiotic VSL#3 in a Phase …
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CLINICAL_TRIALS trial_result · 2011-11-11Clinical Trial Update: Effects of a Very Low Carbohydrate Diet on Symptoms of Irritable Bowel Syndrome (IBS) [NA]
Completed clinical trial evaluating the effects of a very low carbohydrate diet on symptoms of diarrhea-predominant irritable bowel syndrome…
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CLINICAL_TRIALS research · 2011-06-14Clinical Trial Update: The Effects of Soy Dietary Fiber in Adults With Diarrhea Predominant Irritable Bowel Syndrome [NA]
This clinical trial update describes a study examining the effects of soy dietary fiber in adults with diarrhea-predominant irritable bowel …
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FDA approval · 2008-04-01FDA Approved: LOTRONEX — Supplemental Application (Legacy Pharma USA Inc.)
FDA approved a supplemental application for Lotronex (alosetron hydrochloride) from Legacy Pharma USA Inc.