Irreversible Pulpitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Vital Pulp Therapy Versus Root Canal Treatment for Irreversible Pulpitis With Incipient Apical Periodontitis Diagnosed Using Artificial Intelligence This Keeps: the Main Intervention (Vital Pulp Therapy) the Comparison (Root Canal Treatment) the Condition (Irreversible Pulpitis With Incipient Apic [NA]
A clinical trial at Ain Shams University comparing vital pulp therapy to root canal treatment for symptomatic irreversible pulpitis with inc…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Effect of Instrumentation Systems and Sealers on Postoperative Pain [NA]
A clinical trial evaluating how instrumentation systems and sealers affect postoperative pain in irreversible pulpitis.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: SCN9A Gene Expression and Inflammatory Cytokines
This document provides an update on a clinical trial examining SCN9A gene expression and inflammatory cytokines in irreversible pulpitis, wi…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker [NA]
This clinical trial update notes an ongoing study evaluating metabolic biomarkers to predict vital pulp treatment outcomes in symptomatic pu…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Regenerative Potentials of Mature Mandibular Molars With Symptomatic Irreversible Pulpitis Enhanced With Different Scaffolds [NA]
A Cairo University-sponsored clinical trial is evaluating regenerative potentials of mature mandibular molars with symptomatic irreversible …
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis [NA]
A Cairo University-led clinical trial is evaluating epigallocatechin gallate (EGCG) as a flushing agent during full pulpotomy for irreversib…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Evaluation of Bacterial Reduction After Pulpectomy in Primary Molars [NA]
This clinical trial update describes a study evaluating bacterial reduction after pulpectomy in primary molars for Irreversible pulpitis, cu…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Professional Practices Regarding Treatment of Non-vital Primary Teeth Among Dental Surgeons in France
A France-based clinical trial evaluating professional practices among dental surgeons for treating non-vital primary teeth, including cases …
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Postoperative Pain After Pulpectomy in Primary Molars [NA]
Clinical trial update from Cairo University on postoperative pain following pulpectomy in primary molars for irreversible pulpitis; the stud…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: CGF Partial Pulpotomy Versus Endodontic Treatment [NA]
This ClinicalTrials.gov entry from Minia University compares partial pulpotomy to endodontic treatment for irreversible pulpitis and indicat…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Child's Behavior Using Single Rotary File System Versus Manual Instrumentation in Pulpectomy of Primary Molars [NA]
A clinical trial comparing the single rotary file system to manual instrumentation for pulpectomy in primary molars, assessing child behavio…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: In Vivo Pulp Thermal Changes During Different Slenderization Techniques [NA]
This clinical trial update investigates how different slenderization techniques affect in vivo pulp thermal changes in teeth with irreversib…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Effect of Cryotherapy on Anesthetic Success and Pain in Irreversible Pulpitis [NA]
A clinical trial is evaluating whether cryotherapy improves anesthetic success and reduces pain in irreversible pulpitis, with the study cur…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis [NA]
This clinical trial update shows that recruitment is ongoing for a study comparing pulpotomy and root canal treatment in teeth with symptoma…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: The Role of the Pre-operative Condition and Artificial Intelligence-Assisted Diagnosis in Predicting the Success of Full Pulpotomy in Symptomatic Permanent Mature Molars [NA]
This clinical trial update examines whether pre-operative dental condition and AI-assisted diagnosis can predict the success of full pulpoto…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: To Evaluate Post Operative Pain Using Two Different Kind of Sealers in Obturation of Teeth With Symptomatic Irreversible Pulpitis During Second Visit When the Patient is Painless [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating two different sealer materials for root canal obturation in teeth with symptomatic irreversible pulpitis…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars [NA]
Update on a clinical trial evaluating lesion sterilization tissue repair versus conventional pulpectomy in primary molars; the study is curr…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Clinical and Radiographic Outcomes of Rotary Instrumentation in Primary Molars [NA]
A clinical trial update describing rotary instrumentation in primary molars for pulpectomy in irreversible pulpitis, currently NOT_YET_RECRU…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Effect of Menstrual Phase on the Anesthetic Efficacy [NA]
A clinical trial studying whether menstrual phase affects the efficacy of anesthesia in irreversible pulpitis. The study is currently recrui…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Neurokinin A and Matrix Metalloproteinase 9 Levels in Gingival Crevicular Fluid Samples of Teeth With Symptomatic Irreversible Pulpitis With Symptomatic Apical Periodontitis
This clinical trial entry describes a study measuring neurokinin A and matrix metalloproteinase-9 levels in gingival crevicular fluid from t…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Comparison of Aquaporin -4, -5, -9 and IL-8 Levels in GCF, Dentin Fluid and Pulp Samples
A clinical trial from Kırıkkale University is evaluating levels of Aquaporin-4, -5, -9 and IL-8 in gingival crevicular fluid, dentin fluid, …
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Effect of Instrumentation Kinematics on Intraoperative and Post-operative Pain in Maxillary Premolars With Acute Irreversible Pulpitis [NA]
This clinical trial by Al-Azhar University is recruiting to assess how different instrumentation kinematics during endodontic procedures aff…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Evaluation of the Effects of Different Irrigation Solutions and Activation Methods on Postoperative Pain and Quality of Life in Root Canal Treatment [NA]
This clinical trial evaluates how different irrigation solutions and activation methods affect postoperative pain and quality of life after …
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy
This clinical trial investigates how genetic polymorphisms influence the success of vital pulp therapy in dental patients.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Comparison of Pain Between Supraperiosteal Injection of Dexamethasone Versus Placebo on Postoperative Pain in Teeth With Symptomatic Irreversible Pulpitis [NA]
The study compares supraperiosteal dexamethasone injection versus placebo for postoperative pain in teeth with symptomatic irreversible pulp…