Iron Overload
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-07-24Clinical Trial Update: Non-invasive Quantification of Liver Iron With MRI [NA]
A completed clinical trial evaluating non-invasive quantification of liver iron using MRI, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Oral Nifedipine to Treat Iron Overload [Phase 1]
A Phase 1 trial evaluating oral nifedipine for treating iron overload in thalassemia has completed.
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Effects of Taking Prenatal Vitamin-mineral Supplements During Lactation on Iron Status and Markers of Oxidation [NA]
This completed clinical trial evaluated whether taking prenatal vitamin-mineral supplements during lactation affects iron status and markers…
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CLINICAL_TRIALS trial_result · 2017-01-31Clinical Trial Update: Safety and Efficacy of Iron Reduction by Phlebotomy [Phase 2]
Phase 2 clinical trial evaluating the safety and efficacy of reducing iron levels by phlebotomy in patients with iron overload; study comple…
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CLINICAL_TRIALS trial_result · 2017-01-11Clinical Trial Update: Pharmacokinetic Study of Deferiprone in Paediatric Patients [Phase 2]
Phase 2 pharmacokinetic study of deferiprone in paediatric patients with chronic iron overload has been completed, with results posted.
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CLINICAL_TRIALS trial_result · 2016-11-17Clinical Trial Update: Efficacy and Safety of Oral Deferasirox (20 mg/kg/d) in Pts 3 to 6 Months After Allogeneic Hematopoietic Cell Transplantation Who Present With Iron Overload [Phase 4]
Phase 4 study evaluating the efficacy and safety of oral deferasirox in iron overload patients 3-6 months after allogeneic hematopoietic cel…
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CLINICAL_TRIALS trial_result · 2016-10-26Clinical Trial Update: Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients [NA]
This document reports a clinical trial evaluating amlodipine as an adjuvant to iron chelation to prevent cardiac iron overload in beta-thala…
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CLINICAL_TRIALS trial_result · 2016-06-15Clinical Trial Update: Effects of Phlebotomy on Insulin Sensitivity in Insulin Resistance-associated Hepatic Iron Overload Patients [NA]
This completed clinical trial evaluated whether phlebotomy improves insulin sensitivity in patients with insulin resistance and iron overloa…
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: Hemochromatosis and Iron Overload Screening Study (HEIRS)
The Hemochromatosis and Iron Overload Screening Study (HEIRS), sponsored by NHLBI, has completed. The study examined screening for hemochrom…
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CLINICAL_TRIALS trial_result · 2015-09-09Clinical Trial Update: Amlodipine in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major [Phase 3]
Phase 3 trial evaluating amlodipine for prevention and treatment of iron overload in patients with thalassemia major; the study has complete…
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CLINICAL_TRIALS trial_result · 2015-09-01Clinical Trial Update: Renal Function Among Thalassemia Patients Treated by a Oral Chelator Deferasirox
A completed clinical trial evaluating renal function in thalassemia patients with iron overload treated with the oral chelator deferasirox.
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CLINICAL_TRIALS trial_result · 2015-08-17Clinical Trial Update: Pharmacokinetics of SSP-004184 in the Treatment of Chronic Iron Overload Requiring Chelation Therapy [Phase 2]
Phase 2 pharmacokinetics study of SSP-004184 for iron overload due to chronic transfusion-dependent conditions was terminated with results p…
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Phlebotomy and Risk of Hepatocellular Carcinoma in Patients With Compensated Alcoholic Cirrhosis [Phase 3]
Phase 3 trial evaluating phlebotomy to reduce hepatocellular carcinoma risk in patients with compensated alcoholic cirrhosis and iron overlo…
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CLINICAL_TRIALS trial_result · 2015-03-10Clinical Trial Update: Rare Iron Overloads Except C282Y Homozygosity : Description and Characterization.
A Rennes University Hospital-sponsored trial investigating rare iron overload disorders excluding C282Y homozygosity has been terminated; th…
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CLINICAL_TRIALS trial_result · 2014-10-28Clinical Trial Update: Safety and Efficacy of Desferasirox in Chinese Patients With Iron Overload and Aplastic Anemia [Phase 4]
Phase 4 study assessing the safety and efficacy of Desferasirox in Chinese patients with iron overload and aplastic anemia.
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CLINICAL_TRIALS trial_result · 2014-07-17Clinical Trial Update: MR Imaging of Diffuse Myocardial Fibrosis in Transfusion-Dependent Anemias
This update reports the completion of a clinical trial evaluating MR imaging to detect diffuse myocardial fibrosis in transfusion-dependent …
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CLINICAL_TRIALS trial_result · 2013-11-26Clinical Trial Update: Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis [Phase 2]
Phase 2 trial evaluating subcutaneous desferrioxamine for transfusional iron overload has completed, including patients with beta-thalassemi…
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CLINICAL_TRIALS trial_result · 2013-06-11Clinical Trial Update: Retrospective Evaluation of Adult and Pediatric Transfusion-dependent Patients Treated With Deferasirox Therapy
This retrospective study evaluated outcomes in adult and pediatric transfusion-dependent patients treated with deferasirox for iron overload…
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CLINICAL_TRIALS trial_result · 2012-05-21Clinical Trial Update: Cytochrome P450 2E1 and Iron Overload [Phase 2]
Phase 2 clinical trial evaluating the role of cytochrome P450 2E1 in iron overload and insulin resistance has been completed.
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CLINICAL_TRIALS trial_result · 2012-05-01Clinical Trial Update: Open-Label Single-Arm Pilot Study in Adult Allogeneic Hematopoietic Stem Cell Transplant Recipients With Transfusional Iron Overload [Phase 4]
Open-label, single-arm Phase 4 pilot trial in adults who underwent allogeneic hematopoietic stem cell transplantation with transfusional iro…
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CLINICAL_TRIALS trial_result · 2011-08-11Clinical Trial Update: Safety and Efficacy of Deferasirox in Patients With Transfusion Dependent Iron Overload - a Non-comparative Extension Study [Phase 2, Phase 3]
A non-comparative extension trial assesses safety and efficacy of deferasirox in transfusion-dependent iron overload with liver involvement;…
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CLINICAL_TRIALS trial_result · 2011-07-29Clinical Trial Update: Extension Study of the Efficacy and Safety of Deferasirox Treatment in Beta-thalassemia Patients With Transfusional Hemosiderosis (Study Amended to 2-year Duration) [Phase 4]
This Phase 4 extension study evaluates the efficacy and safety of deferasirox in transfusion-dependent beta-thalassemia patients with iron o…
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CLINICAL_TRIALS trial_result · 2011-06-14Clinical Trial Update: Efficacy and Safety of Desferal Versus Osveral in Transfusional Iron Overload [NA]
A completed clinical trial compared the efficacy and safety of the iron chelators deferoxamine (Desferal) and deferasirox (Osveral) for tran…
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CLINICAL_TRIALS trial_result · 2011-05-18Clinical Trial Update: Safety and Efficacy of Deferasirox (ICL670) in Patients With Iron Overload Resulting From Hereditary Hemochromatosis [Phase 1, Phase 2]
Phase 1/2 clinical trials evaluated the safety and efficacy of Deferasirox (ICL670) for iron overload caused by hereditary hemochromatosis, …
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CLINICAL_TRIALS trial_result · 2011-05-02Clinical Trial Update: Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients [Phase 2]
Phase 2 trial comparing deferasirox with subcutaneous deferoxamine in patients with sickle cell disease and iron overload; results were post…