Iron Overload
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Focal Accumulation of Iron in Cerebral Regions in Early ALS (Amyotrophic Lateral Sclerosis) Patients [Phase 2]
Phase 2 trial evaluating focal iron accumulation in cerebral regions of early amyotrophic lateral sclerosis patients has completed, examinin…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Confounder-Corrected Quantitative MRI Biomarker of Hepatic Iron Content
A University of Wisconsin–Madison trial evaluating a confounder-corrected quantitative MRI biomarker of hepatic iron content has completed.
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Risk Factors and Measures to Prevent Liver and Pancreas Complications in Pediatric Patients After HSCT
A completed clinical trial evaluating risk factors for liver and pancreas complications and strategies to prevent them in pediatric patients…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: Long-term Clinical Study of CN128 in Thalassemia With Sever Liver Iron Overloaded Patients [Phase 2]
An update on the Phase 2 long-term study of CN128 in patients with thalassemia and severe liver iron overload, which has completed.
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Inhibitory Effect of a Polyphenol Supplement on Dietary Iron Absorption in Adults with Thalassemia [NA]
A completed clinical trial evaluating whether a polyphenol supplement inhibits dietary iron absorption in adults with thalassemia and iron o…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Safety of SP-420 in the Treatment of Transfusional Iron Overload [Phase 1]
Phase 1 trial evaluating safety of SP-420 for transfusional iron overload has been terminated.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload [Phase 2]
A Phase 2 study evaluating an improved deferasirox granule formulation for treatment compliance, efficacy, and safety in pediatric patients …
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: MRI QSM Imaging for Iron Overload
The trial completed an evaluation of MRI quantitative susceptibility mapping (QSM) imaging as a noninvasive method to quantify iron overload…
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CLINICAL_TRIALS trial_result · 2024-03-15Clinical Trial Update: Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young Children [Phase 4]
A Phase 4 trial evaluating safety and efficacy of early deferiprone treatment in infants and young children with beta-thalassemia major anem…
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias [Phase 4]
Phase 4 trial assessing long-term safety and efficacy of Ferriprox in iron-overloaded patients, including those with sickle cell disease and…
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Long-term Clinical Study of CN128 in Thalassemia Patients [Phase 2]
Phase 2 long-term clinical study update for CN128 in thalassemia and iron overload conditions has completed.
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CLINICAL_TRIALS trial_result · 2023-05-23Clinical Trial Update: Phlebotomy and Lifestyle and Diet Advices vs Lifestyle and Diet Advices Only in Patients With Dysmetabolic Liversiderosis [Phase 3]
Phase 3 trial comparing phlebotomy plus lifestyle and diet advice versus lifestyle and diet advice alone in patients with dysmetabolic liver…
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CLINICAL_TRIALS trial_result · 2023-02-09Clinical Trial Update: Ferrochelating Treatment in Patients Affected by Neurodegeneration With Brain Iron Accumulation (NBIA) [Phase 2]
Phase 2 clinical trial evaluating ferrochelating treatment in patients with neurodegeneration with brain iron accumulation (NBIA).
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CLINICAL_TRIALS trial_result · 2022-09-21Clinical Trial Update: Chelation Therapy of Iron Overload With Pyridoxal Isonicotinoyl Hydrazone [Phase 2]
Phase 2 clinical trial update on chelation therapy using Pyridoxal Isonicotinoyl Hydrazone for iron overload in anemia due to beta-thalassem…
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CLINICAL_TRIALS trial_result · 2021-08-16Clinical Trial Update: Study of Deferasirox for Treatment of Transfusional Iron Overload in Myelodysplastic Patients [Phase 2]
Phase 2 clinical trial evaluating deferasirox for treating transfusional iron overload in patients with myelodysplastic syndrome has complet…
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CLINICAL_TRIALS trial_result · 2021-08-12Clinical Trial Update: Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload [Phase 2]
Phase 2 trial update on combined chelation therapy for transfusion-dependent thalassemia with iron overload; study completed with posted res…
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CLINICAL_TRIALS trial_result · 2021-08-10Clinical Trial Update: Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias [Phase 4]
Phase 4 clinical trial update on ferriprox for iron overload and sickle cell disease/other anemias; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-06-24Clinical Trial Update: Study for the Treatment of Transfusional Iron Overload in Myelodysplastic Patients [Phase 4]
Phase 4 clinical trial update for treating transfusional iron overload in patients with myelodysplastic syndromes; study completed with resu…
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: Cardiac T2* in Beta-thalassemia Patients on Deferasirox Treatment [Phase 2]
Phase 2 trial update on cardiac T2* in beta-thalassemia patients treated with deferasirox; results posted after completion.
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Efficacy/Safety Study of Deferiprone Compared to Deferasirox in Paediatric Patients [Phase 3]
Phase 3 trial comparing deferiprone to deferasirox in pediatric patients with chronic iron overload has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: Hydroxy Urea, Omega 3, Nigella Sativa,Honey on Oxidative Stress and Iron Chelation in Pediatric Major Thalassemia [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating hydroxyurea, omega-3, Nigella sativa, and honey for iron overload and oxidative stress in pediatric major t…
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: Safety Study of Crushed Deferasirox Film Coated Tablets in Pediatric Patients With Transfusional Hemosiderosis [Phase 4]
Phase 4 safety study of crushed deferasirox film-coated tablets in pediatric patients with transfusional iron overload completed; results po…
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CLINICAL_TRIALS trial_result · 2020-03-03Clinical Trial Update: Extended Evaluation of Deferasirox Film-coated Tablet (FCT) Formulation [Phase 3]
Phase 3 trial update on extended evaluation of deferasirox film-coated tablet formulation for chronic iron overload; results posted after co…
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CLINICAL_TRIALS trial_result · 2019-05-29Clinical Trial Update: Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload [Phase 2]
Phase 2 trial of deferasirox for iron overload in patients who underwent allogeneic stem cell transplant was terminated; results posted in 2…
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CLINICAL_TRIALS trial_result · 2018-04-11Clinical Trial Update: Iron Overload in Pediatric Oncology Patients
This clinical trial update notes the completion of a study examining iron overload in pediatric oncology patients.