Invasive Aspergillosis
📧 Sign up to get email alerts when something new happens for Invasive Aspergillosis.
Sign up freeTop drugs studied for this disease
-
FDA label_change · 2015-04-03FDA Approved: CRESEMBA — Supplemental Application (Astellas Pharma US, Inc.)
FDA notice of a supplemental application for CRESEMBA (isavuconazonium sulfate) submitted by Astellas Pharma US, Inc., indicating a potentia…
-
CLINICAL_TRIALS trial_result · 2015-03-31Clinical Trial Update: Isavuconazole (BAL8557) for Primary Treatment of Invasive Aspergillosis [Phase 3]
Phase 3 trial results for isavuconazole (BAL8557) as primary treatment for invasive aspergillosis have been posted.
-
FDA approval · 2015-03-06FDA Approved: CRESEMBA — Original Application (Astellas Pharma US, Inc.)
FDA approves Cresemba (isavuconazonium sulfate) under an original application for the treatment of invasive aspergillosis and mucormycosis.
-
FDA approval · 2015-03-06FDA Approved: CRESEMBA — Original Application (Astellas Pharma US, Inc.)
FDA approved CRESEMBA (isavuconazonium sulfate) from Astellas Pharma US, Inc. as an antifungal treatment. The approval covers invasive asper…
-
FDA approval · 2015-02-03FDA Approved: VFEND — Supplemental Application (Roerig)
FDA approved a supplemental application for VFEND (voriconazole) from Roerig, resulting in an update/expansion of the product's labeling.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2015-01-13Clinical Trial Update: MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037) [Phase 2]
Phase 2 clinical trial evaluating MK0991 in combination with standard antifungal therapy for salvage invasive aspergillosis has completed.
-
CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Diagnostic and Management Strategies for Invasive Aspergillosis
A completed clinical trial evaluating diagnostic and management strategies for invasive aspergillosis, including considerations for neutrope…
-
CLINICAL_TRIALS trial_result · 2014-08-15Clinical Trial Update: Effect of Inflammation on Voriconazole Concentration
A completed clinical trial reports that inflammation can alter voriconazole concentrations, potentially affecting dosing for invasive fungal…
-
CLINICAL_TRIALS trial_result · 2014-06-23Clinical Trial Update: A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In Children [Phase 3]
Pfizer carried out a Phase 3 safety study of voriconazole in children with invasive aspergillosis and other rare molds; the trial was termin…
-
FDA approval · 2014-04-07FDA Approved: VFEND — Supplemental Application (Roerig)
FDA approved a supplemental application for VFEND (voriconazole) submitted by Roerig.
-
CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Galactomannan Antigen in Bronchoalveolar Lavage in the Diagnosis of Invasive Aspergillosis in Neutropenic Patients
A completed clinical trial evaluating galactomannan antigen in bronchoalveolar lavage for diagnosing invasive aspergillosis in neutropenic p…
-
CLINICAL_TRIALS trial_result · 2014-01-29Clinical Trial Update: Validation of an Index of Neutropenia (D-index) in Febrile Neutropenic Cancer Patients [NA]
This clinical trial update notes termination of a study validating the D-index neutropenia measure in febrile neutropenic cancer patients, w…
-
FDA approval · 2013-12-18FDA Approved: CANCIDAS — Supplemental Application (Merck Sharp & Dohme LLC)
FDA approved a supplemental application for CANCIDAS (caspofungin acetate) from Merck Sharp & Dohme LLC to update its labeling.
-
FDA approval · 2013-11-25FDA Approved: NOXAFIL — Original Application (Merck Sharp & Dohme LLC)
FDA approves NOXAFIL (posaconazole) through Merck's original NDA. The approval recognizes posaconazole for prevention and treatment of invas…
-
CLINICAL_TRIALS trial_result · 2013-09-05Clinical Trial Update: Micafungin Salvage Mono-therapy in Invasive Aspergillosis [Phase 2]
A Phase 2 trial of micafungin as salvage monotherapy for invasive aspergillosis has been terminated.
-
CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: A Multicentre Randomised Controlled Trial Comparing Two Strategies for the Diagnosis of Invasive Aspergillosis in High-risk Haematology Patients [Phase 3]
A Phase 3 multicenter randomized trial comparing two diagnostic strategies for invasive aspergillosis in high-risk hematology patients has c…
-
CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: Caspofungin Maximum Tolerated Dose in Patients With Invasive Aspergillosis [Phase 2]
Phase 2 trial update determining the maximum tolerated dose of caspofungin in patients with invasive aspergillosis; results were posted.
-
CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant [Phase 2]
A Phase 2 trial evaluating caspofungin acetate for treating aspergillosis in patients with hematologic cancer or after stem cell transplanta…
-
CLINICAL_TRIALS trial_result · 2012-07-02Clinical Trial Update: Comparison of Voriconazole and Amphotericin B in Treating Patients With Aspergillosis [Phase 3]
Phase 3 trial comparing voriconazole to amphotericin B in patients with invasive aspergillosis has completed.
-
FDA approval · 2012-05-30FDA Approved: VORICONAZOLE — Original Application (Sandoz Inc)
The FDA approved Sandoz Inc's original application for a generic Voriconazole, enabling its marketing in the United States for the same indi…
-
CLINICAL_TRIALS withdrawal · 2012-05-11Clinical Trial Update: Voriconazole And Anidulafungin Combination For Invasive Aspergillosis In Pediatric Subjects [Phase 3]
A Phase 3 clinical trial evaluating a voriconazole and anidulafungin combination for invasive aspergillosis in pediatric subjects has been w…
-
CLINICAL_TRIALS trial_result · 2012-04-30Clinical Trial Update: Anidulafungin Plus Voriconazole Versus Voriconazole For The Treatment Of Invasive Aspergillosis [Phase 3]
A Phase 3 trial comparing the combination of anidulafungin and voriconazole to voriconazole alone for invasive aspergillosis has completed a…
-
CLINICAL_TRIALS withdrawal · 2012-04-20Clinical Trial Update: Trial of Combination Antifungal Therapy (Vori+Mica vs. Vori+Placebo) in Invasive Aspergillosis [Phase 2]
A Phase 2 trial evaluating voriconazole plus micafungin versus voriconazole plus placebo for invasive aspergillosis was withdrawn.
-
CLINICAL_TRIALS trial_result · 2011-08-26Clinical Trial Update: A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED) [Phase 3]
A Phase 3 study evaluating caspofungin (MK0991) in Japanese patients with invasive Candida or invasive Aspergillus infections has completed,…
-
CLINICAL_TRIALS trial_result · 2011-08-19Clinical Trial Update: Influence of Drug-drug Interactions on the Pharmacokinetics (PK) of Voriconazole [Phase 1]
Completed Phase 1 study evaluating how drug-drug interactions affect the pharmacokinetics of voriconazole in patients with invasive aspergil…