Invasive Aspergillosis
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: COVID-19 Associated Pulmonary Aspergillosis (CAPA) and Other Invasive Fungal Infections (IFI)
Clinical trial update noting that the study on COVID-19 associated pulmonary aspergillosis and other invasive fungal infections has complete…
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Incidence of Invasive Pulmonary Aspergillosis in Ventilator-associated Pneumonia
A completed clinical trial update reports on the incidence of invasive aspergillosis in patients with ventilator-associated pneumonia.
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: A Study to Understand How the Use of Paxlovid Affected the Healthcare Use in People With Pre-existing Conditions.
This completed trial evaluated whether Paxlovid (nirmatrelvir/ritonavir) influenced healthcare utilization in people with pre-existing condi…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Performance Evaluation of the Fujifilm Wako Beta-D-glucan Technique in the Diagnosis of Major Invasive Fungal Infections (IFI)
This clinical trial update evaluates the performance of the Fujifilm Wako beta-D-glucan assay in diagnosing major invasive fungal infections…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Prospective Multicenter Evaluation of the MycoGenie Kit for the Diagnosis of Invasive Aspergillosis
A prospective multicenter evaluation of the MycoGenie Kit for diagnosing invasive aspergillosis in patients with onco-hematological diseases…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Cresemba® in Treating Chinese Patients With IFD Caused by Aspergillus Species or Other Filamentous Fungi [Phase 4]
Phase 4 trial update indicating completion of the study of Pfizer's Cresemba (posaconazole) for invasive fungal disease due to Aspergillus s…
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: European Study of Cerebral Aspergillosis Treated With Isavuconazole
This completed European trial evaluates isavuconazole for cerebral aspergillosis, within the broader context of invasive aspergillosis.
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: A Study of ABCD for Injection in Subjects With Invasive Candidiasis and Invasive Aspergillus [Phase 3]
Phase 3 trial of ABCD for Injection for invasive candidiasis and invasive aspergillosis has completed.
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104) [Phase 2]
A Phase 2 trial evaluating intravenous and oral posaconazole (MK-5592) in children with invasive aspergillosis has completed, with results p…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: T Lymphocytes for the Treatment of AdV, CMV, EBV, BKV and Aspergillus Fumigatus Infections After Allogeneic Stem Cell Transplantation [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating donor-derived T lymphocytes for infections caused by adenovirus, cytomegalovirus, Epstein-Barr virus,…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Post Marketing Study to Evaluate the Efficacy and Safety of Micafungin Treatment on Invasive Aspergillosis [Phase 4]
A Phase 4 post-marketing study evaluating the efficacy and safety of micafungin for invasive aspergillosis has been terminated.
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Assessing Diagnostic Methods for Invasive Fungal Disease in Lung Transplant Recipients
A completed clinical trial evaluating diagnostic methods for invasive fungal disease in lung transplant recipients.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Evaluate Safety and Efficacy of the Coadministration of Ibrexafungerp With Voriconazole in Patients With Invasive Pulmonary Aspergillosis [Phase 2]
Phase 2 trial evaluating safety and efficacy of coadministering ibrexafungerp with voriconazole in invasive aspergillosis was terminated, wi…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Novel Biomarkers for Invasive Aspergillosis [NA]
Clinical trial investigating novel biomarkers for invasive aspergillosis was terminated; no results reported in this update.
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Azole-echinocandin Combination Therapy for Invasive Aspergillosis [Phase 3]
A Phase 3 trial evaluating azole-echinocandin combination therapy for invasive aspergillosis has been terminated.
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: A Study to Evaluate Isavuconazonium Sulfate for the Treatment of Invasive Aspergillosis (IA) or Invasive Mucormycosis (IM) in Pediatric Participants [Phase 2]
This update reports the results of a Phase 2 pediatric study evaluating isavuconazonium sulfate for invasive aspergillosis and invasive muco…
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CLINICAL_TRIALS trial_result · 2023-05-19Clinical Trial Update: Open-label Study of APX001 for Treatment of Patients With Invasive Mold Infections Caused by Aspergillus or Rare Molds [Phase 2]
Phase 2 open-label study of APX001 (fosmanogepix) for invasive mold infections including Aspergillus; the trial was terminated and results w…
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CLINICAL_TRIALS trial_result · 2020-11-03Clinical Trial Update: CYP2C19 Genotype-Specific Dosing Plus TDM on Reaching Therapeutic Voriconazole Blood Levels [Phase 4]
Phase 4 trial evaluating CYP2C19 genotype-specific dosing with therapeutic drug monitoring to achieve therapeutic voriconazole levels in inv…
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Amphotericin B Cholesteryl Sulfate Complex for Injection(ABCD) in the Treatment of Invasive Candidiasis and Invasive Aspergillosis [Phase 2]
Phase 2 clinical trial update for Amphotericin B cholesteryl sulfate complex for injection (ABCD) in invasive candidiasis and invasive asper…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: Exhaled Breath Analysis in the Early Detection of Aspergillosis
A completed clinical trial evaluating exhaled breath analysis for early detection of invasive aspergillosis.
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CLINICAL_TRIALS trial_result · 2018-01-10Clinical Trial Update: Study of FK463 for the Treatment of Invasive Aspergillosis [Phase 2]
Phase 2 clinical trial update for FK463 in the treatment of invasive aspergillosis has been completed.
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CLINICAL_TRIALS trial_result · 2017-05-23Clinical Trial Update: Multiple Ascending Oral Dose Study of F901318 in Healthy Subjects [Phase 1]
Phase 1 study assessing multiple ascending oral doses of F901318 in healthy volunteers has completed.
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Concentrations of Voriconazole in Blood and BAL-fluid After Inhalation and Oral Administration [NA]
The trial compared concentrations of voriconazole in blood and bronchoalveolar lavage fluid after inhaled versus oral administration in inva…
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CLINICAL_TRIALS trial_result · 2017-02-02Clinical Trial Update: Study of Potential for Interaction of Fluconazole With F901318 [Phase 1]
A Phase 1 study completed to assess potential pharmacokinetic interaction between fluconazole and F901318 in invasive aspergillosis.
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CLINICAL_TRIALS trial_result · 2016-11-28Clinical Trial Update: Evaluation of Immediate Release Tablet [Phase 1]
Phase 1 clinical trial of an immediate-release tablet for invasive aspergillosis has completed.