Invasive Aspergillosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-09-19Clinical Trial Update: Single Ascending Oral Dose Study of F901318 [Phase 1]
A Phase 1 single ascending oral dose study of F901318 in invasive aspergillosis has been completed.
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CLINICAL_TRIALS trial_result · 2016-09-19Clinical Trial Update: F901318 Multiple Ascending Dose Study [Phase 1]
A Phase 1 multiple ascending dose study of F901318 for invasive aspergillosis has completed.
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Invasives Aspergillosis in Acute Myeloid Leukemia
A clinical trial evaluating invasive aspergillosis in patients with acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2016-06-09Clinical Trial Update: Evaluation of the Potential for Cytochrome P450 3A4 Inhibition by F901318 Using Oral Midazolam as a Probe [Phase 1]
Phase 1 trial completed to evaluate the potential of F901318 to inhibit CYP3A4 using oral midazolam as a probe. The study assesses drug–drug…
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CLINICAL_TRIALS trial_result · 2016-01-11Clinical Trial Update: Isavuconazole in the Treatment of Renally Impaired Aspergillosis and Rare Fungi [Phase 3]
Phase 3 trial update evaluating isavuconazole for renally impaired patients with invasive aspergillosis and rare fungal infections; results …
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CLINICAL_TRIALS trial_result · 2015-10-23Clinical Trial Update: Nebulized Amphotericin B Lipid Complex in Invasive Pulmonary Aspergillosis in Paediatric Patients With Acute Leukaemia [Phase 2]
Phase 2 trial evaluating nebulized amphotericin B lipid complex for invasive aspergillosis in pediatric patients with acute leukemia has com…
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CLINICAL_TRIALS trial_result · 2015-09-07Clinical Trial Update: F901318 Single Ascending Dose Study in Healthy Male Volunteers [Phase 1]
Phase 1 single ascending dose study of F901318 in healthy male volunteers; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-07-09Clinical Trial Update: COMBISTRAT: AmBisome® in Combination With Caspofungin for the Treatment of Invasive Aspergillosis [Phase 4]
A Phase 4 study evaluating the combination of AmBisome (liposomal amphotericin B) with caspofungin for invasive aspergillosis has completed.
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CLINICAL_TRIALS trial_result · 2015-03-31Clinical Trial Update: Isavuconazole (BAL8557) for Primary Treatment of Invasive Aspergillosis [Phase 3]
Phase 3 trial results for isavuconazole (BAL8557) as primary treatment for invasive aspergillosis have been posted.
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CLINICAL_TRIALS trial_result · 2015-01-13Clinical Trial Update: MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037) [Phase 2]
Phase 2 clinical trial evaluating MK0991 in combination with standard antifungal therapy for salvage invasive aspergillosis has completed.
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Diagnostic and Management Strategies for Invasive Aspergillosis
A completed clinical trial evaluating diagnostic and management strategies for invasive aspergillosis, including considerations for neutrope…
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CLINICAL_TRIALS trial_result · 2014-08-15Clinical Trial Update: Effect of Inflammation on Voriconazole Concentration
A completed clinical trial reports that inflammation can alter voriconazole concentrations, potentially affecting dosing for invasive fungal…
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CLINICAL_TRIALS trial_result · 2014-06-23Clinical Trial Update: A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In Children [Phase 3]
Pfizer carried out a Phase 3 safety study of voriconazole in children with invasive aspergillosis and other rare molds; the trial was termin…
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Galactomannan Antigen in Bronchoalveolar Lavage in the Diagnosis of Invasive Aspergillosis in Neutropenic Patients
A completed clinical trial evaluating galactomannan antigen in bronchoalveolar lavage for diagnosing invasive aspergillosis in neutropenic p…
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CLINICAL_TRIALS trial_result · 2014-01-29Clinical Trial Update: Validation of an Index of Neutropenia (D-index) in Febrile Neutropenic Cancer Patients [NA]
This clinical trial update notes termination of a study validating the D-index neutropenia measure in febrile neutropenic cancer patients, w…
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CLINICAL_TRIALS trial_result · 2013-09-05Clinical Trial Update: Micafungin Salvage Mono-therapy in Invasive Aspergillosis [Phase 2]
A Phase 2 trial of micafungin as salvage monotherapy for invasive aspergillosis has been terminated.
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: A Multicentre Randomised Controlled Trial Comparing Two Strategies for the Diagnosis of Invasive Aspergillosis in High-risk Haematology Patients [Phase 3]
A Phase 3 multicenter randomized trial comparing two diagnostic strategies for invasive aspergillosis in high-risk hematology patients has c…
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CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: Caspofungin Maximum Tolerated Dose in Patients With Invasive Aspergillosis [Phase 2]
Phase 2 trial update determining the maximum tolerated dose of caspofungin in patients with invasive aspergillosis; results were posted.
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant [Phase 2]
A Phase 2 trial evaluating caspofungin acetate for treating aspergillosis in patients with hematologic cancer or after stem cell transplanta…
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CLINICAL_TRIALS trial_result · 2012-07-02Clinical Trial Update: Comparison of Voriconazole and Amphotericin B in Treating Patients With Aspergillosis [Phase 3]
Phase 3 trial comparing voriconazole to amphotericin B in patients with invasive aspergillosis has completed.
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CLINICAL_TRIALS trial_result · 2012-04-30Clinical Trial Update: Anidulafungin Plus Voriconazole Versus Voriconazole For The Treatment Of Invasive Aspergillosis [Phase 3]
A Phase 3 trial comparing the combination of anidulafungin and voriconazole to voriconazole alone for invasive aspergillosis has completed a…
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CLINICAL_TRIALS trial_result · 2011-08-26Clinical Trial Update: A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED) [Phase 3]
A Phase 3 study evaluating caspofungin (MK0991) in Japanese patients with invasive Candida or invasive Aspergillus infections has completed,…
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CLINICAL_TRIALS trial_result · 2011-08-19Clinical Trial Update: Influence of Drug-drug Interactions on the Pharmacokinetics (PK) of Voriconazole [Phase 1]
Completed Phase 1 study evaluating how drug-drug interactions affect the pharmacokinetics of voriconazole in patients with invasive aspergil…
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CLINICAL_TRIALS trial_result · 2010-02-15Clinical Trial Update: Study to Test the Combination of Voriconazole and Anidulafungin in Patients Who Have, or Are Thought to Have, Invasive Aspergillosis and Who Are Unable to Take a Common Antifungal Therapy (Polyene) [Phase 4]
A Phase 4 trial evaluating the combination of voriconazole and anidulafungin for invasive aspergillosis in patients unable to take polyene w…
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CLINICAL_TRIALS trial_result · 2009-12-03Clinical Trial Update: Voriconazole Prophylaxis Against Aspergillosis in Lung Transplant Recipients
A completed clinical trial assessing voriconazole as prophylaxis to prevent aspergillosis in lung transplant recipients.