Intrahepatic Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Durvalumab and Tremelimumab With Platinum-based Chemotherapy in Intrahepatic Cholangiocarcinoma (ICC) [Phase 1, Phase 2]
This clinical trial update reports results from a Phase 1/2 study of Durvalumab plus Tremelimumab with platinum-based chemotherapy for intra…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers [Phase 3]
A Phase 3 trial evaluating gemcitabine hydrochloride and cisplatin with or without nab-paclitaxel in newly diagnosed advanced biliary tract …
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Adebrelimab Combined with Irinotecan Liposomes, 5-FU, CF ± Lenvatinib As First-line Treatment for Advanced ICC [Phase 2]
Phase 2 trial evaluating adebrelimab plus irinotecan liposome, 5-FU, and CF with or without lenvatinib as first-line treatment for advanced …
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CLINICAL_TRIALS research · 2024-10-10Clinical Trial Update: Liver Transplant for Stable, Advanced Intrahepatic Cholangiocarcinoma [NA]
A clinical trial is investigating liver transplantation for patients with stable, advanced intrahepatic cholangiocarcinoma. Enrollment is by…
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CLINICAL_TRIALS research · 2024-10-03Clinical Trial Update: Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations [Phase 1]
TYRA-200 is being studied in a Phase 1 trial to assess safety and anti-tumor activity in advanced cholangiocarcinoma with FGFR2 alterations.…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Multi-mode Ablation and Molecular Imaging Multi-omics Study for Digestive-Origin Malignant Liver Tumors [NA]
This clinical trial from Fudan University investigates multi-mode ablation and molecular imaging with multi-omics for digestive-origin malig…
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: Gemcitabine/Cisplatin/Nab-Paclitaxel and Rilvegostomig in Resectable iCCA [Phase 2]
Phase 2 trial update evaluating gemcitabine/cisplatin/nab-paclitaxel with rilvegostomig in resectable cholangiocarcinoma; currently not yet …
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Low-dose Gemcitabine and Cisplatin and PD-1/PD-L1 Antibody Therapy in Intrahepatic Cholangiocarcinoma [Phase 2]
A Phase 2 trial evaluates low-dose gemcitabine and cisplatin with a PD-1/PD-L1 antibody in intrahepatic cholangiocarcinoma; the study is cur…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: An Open-Label, Multiple-Center, Phase IIa/IIb Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of VG161 as Monotherapy and in Combination With Nivolumab for Treatment of Patients With Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma [Phase 2]
Open-label Phase IIa/IIb trial evaluating VG161 as monotherapy and in combination with nivolumab for hepatocellular carcinoma or intrahepati…
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: Living Donor Liver Transplantation for Intrahepatic Cholangiocarcinoma [NA]
This clinical trial entry from Jena University Hospital examines living donor liver transplantation for intrahepatic cholangiocarcinoma, inc…
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: Microwave Ablation Versus Liver Resection for Intrahepatic Cholangiocarcinoma
Ongoing clinical trial comparing microwave ablation to liver resection for intrahepatic cholangiocarcinoma, evaluating overall survival and …
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: GEMOX-HAIC Plus GEM-SYS in Combination With Lenvatinib and PD-1 Inhibitor for Large Unresectable ICC
A clinical trial is evaluating a combination regimen of GEMOX-HAIC plus GEM-SYS with Lenvatinib and a PD-1 inhibitor for large unresectable …
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 study of irinotecan liposome injection in patients with advanced biliary tract cancer has been terminated.
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Combined Therapy Using Gemcitabine and Cisplatin Chemotherapy, Lenvatinib and Adebrelimab for Patients With Advanced and Unresectable Intrahepatic Cholangiocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating a quadruple combination of gemcitabine, cisplatin, lenvatinib, and adebrelimab for advanced, unresectabl…
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Combining Chemoradiotherapy With Sintilimab in First-Line ICC
A clinical trial investigating the addition of sintilimab to chemoradiotherapy as first-line treatment for intrahepatic cholangiocarcinoma; …
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CLINICAL_TRIALS research · 2024-05-24Clinical Trial Update: Precision Medicine in Patients With Unresectable CholAngiocarcinoma: RadioEmbolization and Combined Biological Therapy [Phase 2]
Phase 2 clinical trial evaluating precision medicine approaches combining radioembolization with biological therapy for unresectable intrahe…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Lenvatinib and Adebrelimab Combined With GEMOX in the Perioperative Treatment of Potentially Resectable Intrahepatic Cholangiocarcinoma [Phase 4]
Phase 4 trial evaluating a combination of lenvatinib, adebrelimab, and GEMOX as perioperative treatment for potentially resectable intrahepa…
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CLINICAL_TRIALS trial_result · 2024-03-04Clinical Trial Update: Recombinant Human Adenovirus Type 5 Plus HAIC of FOLFOX for Intrahepatic Cholangiocarcinoma [Phase 4]
Phase 4 clinical trial update evaluating recombinant human adenovirus type 5 combined with HAIC of FOLFOX for intrahepatic cholangiocarcinom…
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: Combined DEB-TACE, Lenvatinib and Pucotenlimab as Conversion Therapy for Unresectable Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 trial evaluating a combo of DEB-TACE, lenvatinib, and pucotenlimab as conversion therapy for unresectable intrahepatic cholangiocarc…
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CLINICAL_TRIALS trial_result · 2023-12-19Clinical Trial Update: Derazantinib in Subjects With FGFR2 Gene Fusion-, Mutation- or Amplification- Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 trial of derazantinib in FGFR2-altered intrahepatic cholangiocarcinoma and related conditions completed; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-11-29Clinical Trial Update: Combined Therapy Using D-TACE, Gemcitabine and Cisplatin, and PD1 Antibody in Advanced and Unresectable Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 clinical trial investigating combined therapy with D-TACE, gemcitabine, cisplatin, and a PD-1 antibody for unresectable intrahepatic…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Combination Therapy of HAIC, Surufatinib and Tislelizumab for Unresectable or Metastatic Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial investigating a combination of hepatic artery infusion chemotherapy (HAIC), surufatinib, and tislelizumab for unresec…
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CLINICAL_TRIALS trial_result · 2023-11-02Clinical Trial Update: Cadonilimab Combined With Gem/Cis as First Line Therapy in Patients With Advanced ICC [Phase 2]
Phase 2 trial update evaluating cadonilimab with gemcitabine/cisplatin as first-line therapy for advanced intrahepatic cholangiocarcinoma.
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Pemigatinib Combined With PD-1 Inhibitor in Unresectable or Metastatic Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 trial evaluating pemigatinib in combination with a PD-1 inhibitor for unresectable or metastatic intrahepatic cholangiocarcinoma is …
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CLINICAL_TRIALS trial_result · 2023-05-31Clinical Trial Update: Cryoablation Combined With Sintilimab Plus Lenvatinib in 1L Treatment of Advanced ICC (CASTLE-ICC-Chemo-free) [Phase 2]
Phase 2 trial evaluating cryoablation with sintilimab and lenvatinib as first-line therapy for advanced intrahepatic cholangiocarcinoma; sta…