Intra-abdominal Infection
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients
Clinical trial results evaluate the Capillary Leak Index as a prognostic biomarker for post-operative abdominal sepsis in critically ill pat…
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients [Phase 2]
A Phase 2 study evaluating Allocetra-OTS for organ failure in adult sepsis patients has completed, examining efficacy, safety, and tolerabil…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: INSPIRE Trial for Abdominal Infections [NA]
The INSPIRE trial evaluating treatment for intra-abdominal infection has completed. Results have been posted on 2025-08-15.
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Diagnostic Performance of the CandID PLUS PCR for the Diagnosis of Intra-abdominal Candidiasis in Critically Ill Patients
This completed clinical trial assesses the diagnostic performance of the CandID PLUS PCR assay for intra-abdominal candidiasis in critically…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Performance of the SeptiCyte LAB Test for Antibiotic Stewardship in Mesenteric Ischemia
A completed clinical trial evaluated the performance of the SeptiCyte LAB diagnostic test to support antibiotic stewardship in patients with…
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Intra-Abdominal Sepsis and Relationship Between Cumulative Fluid Balance and Serum Sodium and Chloride Levels and In-Hospital Mortality
A completed clinical trial evaluating the relationship between cumulative fluid balance, serum sodium and chloride levels, and in-hospital m…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: TriVerity in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis
This is an update on the TriVerity diagnostic trial for emergency department patients with suspected infections and suspected sepsis. The st…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults [Phase 4]
Phase 4 trial results evaluate the efficacy and safety of ceftazidime-avibactam (CAZ-AVI) for carbapenem-resistant Gram-negative infections …
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CLINICAL_TRIALS trial_result · 2018-12-24Clinical Trial Update: Tygacil Drug Use Investigation
Pfizer reports a completed trial investigating tigecycline (Tygacil) for intra-abdominal infections and skin infections, with results posted…
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Study of Ceftolozane/Tazobactam (MK-7625A) in Combination With Metronidazole in Japanese Participants With Complicated Intra-abdominal Infection (MK-7625A-013) [Phase 3]
Phase 3 trial of ceftolozane/tazobactam plus metronidazole in Japanese adults with complicated intra-abdominal infection has completed with …
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CLINICAL_TRIALS trial_result · 2018-04-09Clinical Trial Update: A Study To Determine The Efficacy And Safety Of Tigecycline Compared With Imipenem/Cliastatin to Treat Complicated Intra-Abdominal Infection [Phase 4]
Phase 4 trial comparing tigecycline to imipenem/cilastatin for complicated intra-abdominal infection; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients
Clinical trial update on target-site pharmacokinetics of doripenem at steady state in intubated ICU patients (completed).
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Deescalating Carbapenems in Hospital Setting [Phase 4]
A Phase 4 trial evaluating de-escalation of carbapenems in hospitalized patients with urinary tract, intra-abdominal, and biliary tract infe…
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: A Study to Evaluate the Safety and Effectiveness of Ertapenem Versus Ceftriaxone/Metronidazole in the Treatment of Intra-abdominal Infections in Adults (0826-802) [Phase 3]
A Phase 3 study comparing ertapenem to ceftriaxone plus metronidazole for intra-abdominal infections in adults has completed.
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: the Influence of Prophylactic and Empirical Anti-fungal Treatment in Severe Sepsis Patients With Perforations [Phase 2]
Phase 2 clinical trial evaluating the effect of prophylactic and empirical antifungal therapy in adults with severe sepsis due to intra-abdo…
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CLINICAL_TRIALS trial_result · 2014-12-19Clinical Trial Update: Procalcitonin as a Marker for the Length of Antibiotic Treatment in Peritonitis and Intra-abdominal Infections
A completed trial assessed whether procalcitonin can guide antibiotic duration in secondary or tertiary peritonitis and intra-abdominal infe…
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CLINICAL_TRIALS trial_result · 2013-08-28Clinical Trial Update: A Safety and Efficacy Study of Doripenem in Participants With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Urinary Tract Infections [Phase 4]
A Phase 4 study evaluated the safety and efficacy of doripenem in patients with nosocomial pneumonia, complicated intra-abdominal infections…
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CLINICAL_TRIALS trial_result · 2013-02-26Clinical Trial Update: Autologous Fibrin Glues for Fistulas Closure [Phase 1]
Phase 1 trial evaluating autologous fibrin glue for closure of enterocutaneous fistulas in the setting of intra-abdominal infection; study c…
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CLINICAL_TRIALS trial_result · 2013-02-08Clinical Trial Update: Study Evaluating Zosyn in Hospitalized Patients With Intra-abdominal Infection [Phase 4]
A Phase 4 study evaluating Zosyn (piperacillin/tazobactam) in hospitalized patients with intra-abdominal infection has completed.
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CLINICAL_TRIALS trial_result · 2012-10-24Clinical Trial Update: Study Evaluating the Pharmacokinetics (PK), Safety, and Tolerability of Tigecycline in Patients 8 to 11 Years of Age [Phase 2]
Phase 2 pediatric study evaluating the pharmacokinetics, safety, and tolerability of tigecycline in children aged 8 to 11 years has complete…
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CLINICAL_TRIALS trial_result · 2012-04-16Clinical Trial Update: Colistin and Rifampicin for MDR-Acinetobacter [Phase 3]
Phase 3 trial evaluating colistin plus rifampicin for multidrug-resistant Acinetobacter infections has completed.
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CLINICAL_TRIALS trial_result · 2011-11-29Clinical Trial Update: Pharmacokinetic (PK) and Safety Study of Meropenem in Young Infants With Intra-abdominal Infections [Phase 1, Phase 2]
Phase 1/2 pharmacokinetic and safety study of meropenem in young infants with intra-abdominal infections has completed with results posted.
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CLINICAL_TRIALS trial_result · 2011-08-18Clinical Trial Update: T.E.A. Study Three Days Ertapenem Versus Three Days Ampicillin- Sulbactam [Phase 4]
Phase 4 trial comparing three days of ertapenem to three days of ampicillin-sulbactam for intra-abdominal infection has completed.
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CLINICAL_TRIALS trial_result · 2011-08-02Clinical Trial Update: A Comparative Study of Ampicillin/Sulbactam Versus Moxifloxacin in the Treatment of Complicated Intra-abdominal Infections [Phase 4]
A Phase 4 trial comparing ampicillin/sulbactam to moxifloxacin for complicated intra-abdominal infections has completed.
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CLINICAL_TRIALS trial_result · 2010-04-26Clinical Trial Update: Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) [Phase 4]
Phase 4 randomized trial comparing tigecycline to ceftriaxone plus metronidazole in complicated intra-abdominal infection; study completed w…