Intervertebral Disc Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2026-04-23Clinical Trial Update: Proprio Spine Measurement Tool [NA]
A Duke University-sponsored clinical trial evaluating the Proprio Spine Measurement Tool for various spine conditions has been withdrawn.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: EvaluatIon of Autologous Nucleus Pulposus Cells (aNPC) in Degenerative Disc Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial sponsored by ASTEROGENE Biomedical Co. Ltd. is recruiting to evaluate autologous nucleus pulposus cells (aNPC) fo…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Safety and Performance of the Hexanium TLIF System in the Treatment of Degenerative Disc Disease
A clinical trial evaluating the safety and performance of the Hexanium TLIF System for degenerative disc disease is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Safety and Performance of the SPINEVISION Hexanium ACIF in the Treatment of Cervical Spine Degenerative Disc Disease
The document provides a trial update on the safety and performance of SPINEVISION Hexanium ACIF for cervical spine degenerative disc disease…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Safety and Performance of the SpineVision Posterior Fixation Systems in Thoracolumbar Spinal Treatment
A clinical trial update indicates that the SpineVision posterior fixation systems are being evaluated for safety and performance in thoracol…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Minimally Invasive Decompression and Fusion Versus Open for Degenerative Lumbar Stenosis [NA]
This document provides a trial update on a completed study comparing minimally invasive decompression and fusion versus open surgery for deg…
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CLINICAL_TRIALS withdrawal · 2026-02-27Clinical Trial Update: The Role of Disc Nutrition in the Etiology and Clinical Treatment of Disc Degeneration [NA]
A VA Office of Research and Development–sponsored clinical trial on disc nutrition for disc degeneration has been withdrawn.
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Dose Responsiveness as a Measure of Clinical Effectiveness During Neuromonitored Spine Surgery
ClinicalTrials.gov update indicates an ongoing trial examining dose responsiveness as a measure of clinical effectiveness during neuromonito…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: 5-Year Global Study on MAST™ Minimally Invasive Fusion Procedures to Treat Degenerative Lumbar Spine (MASTERS-D2)
This update notes the completion of the 5-year global study MASTERS-D2 evaluating MAST Minimally Invasive Fusion Procedures for degenerative…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: RenewDisc Trial: Endoscopic Discectomy and Autologous Stem Cell Therapy for Discogenic Low Back Pain
A clinical trial evaluating endoscopic discectomy combined with autologous stem cell therapy (RenewDisc) for discogenic low back pain is cur…
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Efficacy of Intradiscal Injection of Autologous BM-MSC in Worker Patients Affected by Chronic LBP Due to Multilevel IDD [Phase 2]
Phase 2 trial evaluating intradiscal injection of autologous bone marrow-derived mesenchymal stem cells for chronic low-back pain due to mul…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Efficacy of Intradiscal Injection of Autologous BM-MSC in Subjects With Chronic LBP Due to Multilevel Lumbar IDD [Phase 2]
Phase 2 trial assessing intradiscal autologous bone marrow-derived mesenchymal stem cell injections for chronic low back pain due to multile…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: A Post Market Surveillance on INFUSE Bone Graft
A post-market surveillance clinical trial update for INFUSE Bone Graft (rhBMP-2) sponsored by Medtronic Spinal and Biologics, currently recr…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Adjacent Segment Mechanics in Cervical Arthrodesis Patients
This clinical trial update reports on a completed study evaluating adjacent segment mechanics in patients following cervical arthrodesis, in…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: Russian Disc Degeneration Study
A clinical trial studying intervertebral disc degeneration sponsored by Novosibirsk State University has completed.
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CLINICAL_TRIALS research · 2024-10-24Clinical Trial Update: Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure
This clinical trial update indicates that Alphatec Spine's intraoperative monitoring study for the lateral lumbar interbody fusion procedure…
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CLINICAL_TRIALS withdrawal · 2024-07-12Clinical Trial Update: Comparison of Three Approaches of Electrode Placement to Detect Changes in Motor Evoked Potentials During Spine Surgery [NA]
A clinical trial comparing three electrode-placement approaches to detect changes in motor evoked potentials during spine surgery was withdr…
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CLINICAL_TRIALS research · 2024-04-29Clinical Trial Update: VIA Disc Nucleus Pulposus Older Patients Pilot [NA]
An update on the VIA Disc Nucleus Pulposus pilot trial in older patients indicates the study is currently active and not recruiting.
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CLINICAL_TRIALS trial_result · 2021-10-12Clinical Trial Update: Safety and Efficacy With NOVOCART® Disc Plus (ADCT) for the Treatment of Degenerative Disc Disease in Lumbar Spine [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating safety and efficacy of NOVOCART Disc Plus (ADCT) for degenerative disc disease of the lumbar spine.
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CLINICAL_TRIALS trial_result · 2020-10-09Clinical Trial Update: Duloxetine as an Analgesic Agent in Patients Undergoing Elective Spine Surgery [Phase 4]
Phase 4 clinical trial evaluating duloxetine as an analgesic in patients undergoing elective spine surgery for intervertebral disc degenerat…
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CLINICAL_TRIALS research · 2017-11-17Clinical Trial Update: Genotype-related Molecular Targets in the Vitamin D Pathway for Spinal Disc Diseases
This clinical trial investigates genotype-related molecular targets in the vitamin D pathway for intervertebral disc degeneration; the curre…
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CLINICAL_TRIALS research · 2017-08-31Clinical Trial Update: Prospective Study of Safety and Efficacy of InQu® Bone Graft Extender in Lumbar Interbody Fusion Surgery
Prospective clinical study update on the safety and efficacy of InQu Bone Graft Extender in lumbar interbody fusion.
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CLINICAL_TRIALS research · 2016-08-19Clinical Trial Update: Protection of Autonomic Nervous System During Lower Spine Surgical Procedures: A Safety and Feasibility Study [NA]
Clinical trial update describing a safety and feasibility study on protecting the autonomic nervous system during lower spine surgeries; no …
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Trunk Muscles and Lumbar Intervertebral Disc Degeneration in Combat Sports [NA]
A completed clinical trial investigating the relationship between trunk muscles and lumbar intervertebral disc degeneration in combat sports…
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CLINICAL_TRIALS research · 2015-01-14Clinical Trial Update: Autologous Adipose Derived Stem Cell Therapy for Intervertebral Disc Degeneration [Phase 1]
Phase 1 clinical trial evaluating autologous adipose-derived stem cell therapy for intervertebral disc degeneration presenting as low back p…