Immune Thrombocytopenia
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CLINICAL_TRIALS withdrawal · 2025-11-10Clinical Trial Update: Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias [Phase 2]
An extension study of fostamatinib (Syk inhibitor) for posttransplant immune-mediated cytopenias has been withdrawn, including autoimmune he…
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CLINICAL_TRIALS withdrawal · 2025-09-16Clinical Trial Update: The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP) [Phase 1]
Phase 1 trial evaluating HMPL-523 for safety, tolerability, PK, and preliminary efficacy in adults with immune thrombocytopenia, which has b…
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CLINICAL_TRIALS withdrawal · 2025-08-11Clinical Trial Update: Teriflunomide Plus High-dose Dexamethasone as First-line Treatment in Newly Diagnosed Primary Immune Thrombocytopenia [Phase 2]
A Phase 2 trial evaluating teriflunomide plus high-dose dexamethasone as first-line therapy for newly diagnosed immune thrombocytopenia has …
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CLINICAL_TRIALS withdrawal · 2021-10-22Clinical Trial Update: Open-Label Study to Evaluate the Safety and Efficacy of Avatrombopag and Remission Rates in Adults With ITP of ≤6 Months [Phase 3]
Open-label Phase 3 trial evaluating avatrombopag in adults with immune thrombocytopenia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2020-09-14Clinical Trial Update: A Study to Assess the Efficacy and Safety of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP) [Phase 3]
Phase 3 clinical trial evaluating efgartigimod for adult primary immune thrombocytopenia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-08-14Clinical Trial Update: Rituximab and Dexamethasone Followed by Mycophenolate Mofetil or Placebo in Patients With Immune Thrombocytopenia [Phase 3]
Phase 3 clinical trial of rituximab and dexamethasone followed by mycophenolate mofetil or placebo in immune thrombocytopenia was withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-07-17Clinical Trial Update: End of EXTEND: Discontinuation of Medication for Patients With Immune Thrombocytopenia
The EXTEND trial for Immune Thrombocytopenia has terminated and the medication is being discontinued for participants.
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CLINICAL_TRIALS withdrawal · 2016-04-20Clinical Trial Update: All-Trans Retinoic Acid (ATRA) Combining Dexamethasone Versus High-dose Dexamethasone for Initial Treatment of Primary Immune Thrombocytopenia (ITP) [Phase 3]
A Phase 3 trial comparing all-trans retinoic acid plus dexamethasone versus high-dose dexamethasone for initial treatment of primary immune …
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CLINICAL_TRIALS withdrawal · 2016-04-20Clinical Trial Update: The Alteration of Macrophage Function in the Spleen Tissues From Patients With Primary Immune Thrombocytopenia
This clinical trial update notes that the study examining macrophage function in spleen tissue from patients with immune thrombocytopenia ha…
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CLINICAL_TRIALS withdrawal · 2016-04-20Clinical Trial Update: Recombinant Human Thrombopoietin (rhTPO) Combining Rituximab Versus High-dose Dexamethasone for Initial Treatment of Primary Immune Thrombocytopenia (ITP) [Phase 3]
A Phase 3 trial evaluating recombinant human thrombopoietin with rituximab versus high-dose dexamethasone for initial treatment of primary i…
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CLINICAL_TRIALS withdrawal · 2016-04-20Clinical Trial Update: A Multicentre Investigation of 2 Cycles Rituximab Compared With Standard Regimen in Management of Steroid-Resistant/Relapsed Immune Thrombocytopenia （ITP） [Phase 3]
Phase 3 multicentre trial evaluating two cycles of rituximab vs standard regimen for steroid-resistant/relapsed immune thrombocytopenia was …
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CLINICAL_TRIALS withdrawal · 2016-04-20Clinical Trial Update: Recombinant Human Interleukin-11 Combination Low-dose Rituximab in Immune Thrombocytopenia
A clinical trial evaluating recombinant human interleukin-11 in combination with low-dose rituximab for immune thrombocytopenia has been wit…
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CLINICAL_TRIALS withdrawal · 2016-04-20Clinical Trial Update: Alteration of Different Immune Parameters in Immune Thrombocytopenia （ITP） Patients Receiving Eltrombopag Treatment
A clinical trial evaluating immune parameters in immune thrombocytopenia patients treated with eltrombopag has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-04-20Clinical Trial Update: A Multicenter Investigation of Recombinant Human Thrombopoietin (rhTPO) Combining Cyclosporin A Versus Cyclosporin A in Management of Steroid-Resistant/Relapsed Immune Thrombocytopenia （ITP） [Phase 3]
A Phase 3 trial evaluating recombinant human thrombopoietin plus cyclosporin A versus cyclosporin A for steroid-resistant/relapsed immune th…
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CLINICAL_TRIALS withdrawal · 2016-04-20Clinical Trial Update: Different Cycles of High-dose Dexamethasone for Initial Management of Primary Immune Thrombocytopenia (ITP) [Phase 4]
A Phase 4 trial evaluating different cycles of high-dose dexamethasone for initial management of immune thrombocytopenia has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-04-20Clinical Trial Update: High-dose Dexamethasone Combining Thalidomide Versus Dexamethasone Mono-therapy for Management of Newly-diagnosed ITP [Phase 2]
A Phase 2 trial comparing high-dose dexamethasone plus thalidomide versus dexamethasone alone for newly diagnosed immune thrombocytopenia ha…
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CLINICAL_TRIALS withdrawal · 2014-07-28Clinical Trial Update: A Study to Investigate Belimumab for the Treatment of Chronic Immune Thrombocytopenia. [Phase 2]
A Phase 2 clinical trial evaluating belimumab for chronic immune thrombocytopenia was withdrawn.