Immune Reconstitution Inflammatory Syndrome
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: PET Imaging and Lymph Node Assessment of IRIS in People With AIDS
NIAID-sponsored clinical trial evaluating PET imaging and lymph node assessment of Immune Reconstitution Inflammatory Syndrome in people wit…
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CLINICAL_TRIALS trial_result · 2018-01-19Clinical Trial Update: Preventing TB-IRIS in High-risk Patients: a Randomized Placebo-controlled Trial of Prednisone [Phase 3]
A Phase 3 randomized, placebo-controlled trial evaluating prednisone to prevent TB-IRIS in high-risk HIV patients undergoing antiretroviral …
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: Pediatric Urgent Start of Highly Active Antiretroviral Treatment (HAART) [NA]
This Clinical Trial Update reports the completion of a pediatric study evaluating the urgent initiation of highly active antiretroviral ther…
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CLINICAL_TRIALS trial_result · 2015-01-14Clinical Trial Update: Prediction and Pathogenesis of the Immune Reconstitution Inflammatory Syndrome
A completed clinical trial investigated prediction and pathogenesis of immune reconstitution inflammatory syndrome (IRIS) and related opport…
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CLINICAL_TRIALS trial_result · 2014-08-13Clinical Trial Update: Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS) [Phase 4]
Phase 4 trial evaluating corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS) was terminated; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-05-19Clinical Trial Update: IMPAACT P1073: Study of IRIS for Infants and Children Initiating HAART at Int'l Sites
IMPAACT P1073 evaluated Immune Reconstitution Inflammatory Syndrome in infants and children initiating HAART at international sites; the stu…
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CLINICAL_TRIALS withdrawal · 2013-11-25Clinical Trial Update: Paradoxical Tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) Treatment Trial [Phase 2, Phase 3]
A phase 2/3 clinical trial evaluating treatment for paradoxical TB-IRIS has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-05-29Clinical Trial Update: Umbilical Cord Mesenchymal Stem Cells for Immune Reconstitution in HIV-infected Patients [Phase 2]
Phase 2 clinical trial evaluating umbilical cord-derived mesenchymal stem cells for immune reconstitution in HIV-infected patients; current …
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CLINICAL_TRIALS research · 2012-11-27Clinical Trial Update: Maraviroc (CCR5) Antagonism to Decrease the Incidence of the Immune Reconstitution Inflammatory Syndrome in HIV-Infected Patients [NA]
Clinical trial update evaluating maraviroc (CCR5 antagonist) to reduce the incidence of Immune Reconstitution Inflammatory Syndrome in HIV-i…