Idiopathic Short Stature
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: A Study of the Genetic Basis of Response to Growth Hormone Treatment in Children With Idiopathic Short Stature
A terminated clinical trial investigating the genetic basis of how children with idiopathic short stature respond to growth hormone treatmen…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9 [Phase 3]
Phase 3 clinical trial evaluating the safety and efficacy of somapacitan for pediatric growth disorders; results have been posted for condit…
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: Skeletal Muscle Effects of GH in Boys
A completed clinical trial evaluating the effects of growth hormone on skeletal muscle in boys with growth hormone deficiency or idiopathic …
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Evolution of the Quality of Life of Short Statured Children Treated With Growth Hormone : Evaluation at Adult Size
This completed clinical trial from Assistance Publique - Hôpitaux de Paris evaluates the evolution of quality of life at adult size in child…
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CLINICAL_TRIALS trial_result · 2024-01-24Clinical Trial Update: A Trial of YPEG-rhGH in Children With Short Stature [Phase 2]
Phase 2 trial update for YPEG-rhGH in children with short stature, including idiopathic short stature and small for gestational age conditio…
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CLINICAL_TRIALS trial_result · 2023-07-28Clinical Trial Update: A 4 Year Combination Therapy of Growth Hormone and (GnRH) Agonist in Children With a Short Predicted Height [Phase 4]
Phase 4 trial update evaluating combination therapy of Growth Hormone and GnRH agonist in children with idiopathic short stature.
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CLINICAL_TRIALS trial_result · 2020-12-14Clinical Trial Update: Growth Response in Short Children Suffering From a Disease With Growth Retardation and Treated With Somatropin [Phase 2]
Phase 2 trial update evaluating growth response to somatropin in children with idiopathic short stature.
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CLINICAL_TRIALS trial_result · 2018-08-17Clinical Trial Update: Efficacy and Safety of rhGH (Jintropin®) in Pediatric Participants With ISS [Phase 3]
Phase 3 clinical trial update evaluating efficacy and safety of rhGH (Jintropin) in pediatric participants with idiopathic short stature (IS…
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CLINICAL_TRIALS trial_result · 2018-06-07Clinical Trial Update: Aromatase Inhibitors, Alone And In Combination With Growth Hormone In Adolescent Boys With Idiopathic Short Stature [Phase 3]
A Phase 3 trial evaluating aromatase inhibitors alone and with growth hormone in adolescent boys with idiopathic short stature has completed…
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CLINICAL_TRIALS trial_result · 2017-12-20Clinical Trial Update: Short Stature Related Distress [Phase 4]
A Phase 4 clinical trial investigating short stature related distress in idiopathic short stature and self-image issues has completed.
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Bioequivalence of Two Somatropin Products (Norditropin® Versus Genotropin®) in Healthy Adult Volunteers [Phase 1]
A Phase 1 bioequivalence trial comparing Norditropin and Genotropin somatropin in healthy adult volunteers has completed, assessing pharmaco…
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CLINICAL_TRIALS trial_result · 2016-10-18Clinical Trial Update: A Phase 3 Study to Evaluate the Safety and Efficacy of Saizen® in Children With Idiopathic Short Stature (ISS) [Phase 3]
Results from a Phase 3 study evaluating Saizen (somatropin) for safety and efficacy in children with Idiopathic Short Stature have been comp…
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CLINICAL_TRIALS trial_result · 2016-10-18Clinical Trial Update: Somatropin + Leuprorelin vs Somatropin Alone in Pubertal Children With Idiopathic Short Stature [Phase 3]
Phase 3 trial evaluating somatropin with leuprorelin versus somatropin alone in pubertal children with idiopathic short stature has complete…
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CLINICAL_TRIALS trial_result · 2016-10-05Clinical Trial Update: Efficacy and Safety of Recombinant Human Growth Hormone on Height Velocity in Subjects With Idiopathic Short Stature [Phase 3]
Phase 3 trial evaluating the efficacy and safety of recombinant human growth hormone on height velocity in children with idiopathic short st…
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CLINICAL_TRIALS trial_result · 2016-03-24Clinical Trial Update: Efficacy and Safety Study of Sr-hGH in Comparison With Daily hGH in ISS Patients [Phase 2]
Phase 2 study comparing Sr-hGH to daily human growth hormone in idiopathic short stature to establish dosing and assess efficacy and safety;…
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CLINICAL_TRIALS trial_result · 2015-05-29Clinical Trial Update: Efficacy and Safety of DA-3002 in Children With Idiopathic Short Stature [Phase 3]
Phase 3 trial completed evaluating the efficacy and safety of DA-3002 in children with idiopathic short stature, with results posted in 2015…
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Pappalysin 2 (PAPP-A2) Enzyme Replacement [Phase 1]
This update notes the completion of a Phase 1 clinical trial evaluating PAPP-A2 enzyme replacement therapy for idiopathic short stature.
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: Safety and Efficacy of Long-term Somatropin Treatment in Children
Clinical trial update reporting long-term safety and efficacy of somatropin treatment in pediatric patients with growth-related conditions.
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CLINICAL_TRIALS trial_result · 2014-10-02Clinical Trial Update: Pharmacodynamics of CNP During Growth Hormone Treatment
An update on the pharmacodynamic effects of C-type natriuretic peptide during growth hormone treatment in children with pituitary dwarfism o…
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CLINICAL_TRIALS trial_result · 2013-11-13Clinical Trial Update: Individualized, Target-Driven Treatment Of Children With Idiopathic Short Stature [Phase 3]
Pfizer-sponsored Phase 3 clinical trial evaluating an individualized, target-driven treatment approach in children with idiopathic short sta…
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CLINICAL_TRIALS trial_result · 2013-02-18Clinical Trial Update: Ghrelin Levels in Children With Poor Growth
A completed clinical trial investigated ghrelin levels in children with poor growth, including idiopathic short stature and failure to thriv…
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CLINICAL_TRIALS trial_result · 2013-01-03Clinical Trial Update: Biochemical Markers of Growth Response to Growth Hormone Treatment in Children With Idiopathic Short Stature [Phase 4]
This completed Phase 4 trial investigates biochemical markers related to growth hormone response in children with idiopathic short stature.
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CLINICAL_TRIALS trial_result · 2010-12-23Clinical Trial Update: Genotropin Study Assessing Use of Injection Pen [Phase 3]
Pfizer's Genotropin Phase 3 trial evaluating an injection pen for growth hormone deficiency and idiopathic short stature has completed, with…
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CLINICAL_TRIALS trial_result · 2009-09-29Clinical Trial Update: Study to Identify Markers of Insulin Resistance During Growth Hormone Treatment for Short Stature
This clinical trial update describes a Massachusetts General Hospital study to identify biomarkers of insulin resistance during growth hormo…
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CLINICAL_TRIALS trial_result · 2007-03-09Clinical Trial Update: Amendment (g) Unblinded Extension Phase of Somatropin in Patients With Idiopathic Short Stature [Phase 3]
This update describes an amendment to the unblinded extension phase of a Phase 3 trial of somatropin in idiopathic short stature. The study …