Idiopathic Pulmonary Fibrosis
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CLINICAL_TRIALS research · 2016-06-13Clinical Trial Update: Modelling of Quality Life, Clinical and Physiological Measures in Idiopathic Pulmonary Fibrosis
An ongoing clinical trial update describes modeling quality of life, clinical, and physiological outcomes in idiopathic pulmonary fibrosis.
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CLINICAL_TRIALS trial_result · 2016-05-20Clinical Trial Update: A Study to Assess the Safety and Tolerability of N-Acetylcysteine When Administered With Pirfenidone to Participants With Idiopathic Pulmonary Fibrosis (IPF) [Phase 2]
Phase 2 study evaluating the safety and tolerability of combining N-acetylcysteine with pirfenidone in idiopathic pulmonary fibrosis; the tr…
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CLINICAL_TRIALS trial_result · 2016-03-09Clinical Trial Update: Safety Study of Oral Pirfenidone in Patients With Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis [Phase 2]
Phase 2 safety study of oral pirfenidone in patients with idiopathic pulmonary fibrosis and pulmonary fibrosis has completed, with results p…
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: To Evaluate the Effect of Different Doses of SAR156597 Given to Patients With Idiopathic Pulmonary Fibrosis (IPF) [Phase 1, Phase 2]
This update notes that a Phase 1/Phase 2 study evaluating different doses of SAR156597 in Idiopathic Pulmonary Fibrosis has completed.
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FDA approval · 2016-02-04FDA Approved: OFEV — Supplemental Application (Boehringer Ingelheim Pharmaceuticals, Inc.)
FDA approved a supplemental application for OFEV (nintedanib) filed by Boehringer Ingelheim Pharmaceuticals, Inc., expanding its approved us…
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CLINICAL_TRIALS withdrawal · 2016-01-05Clinical Trial Update: A MultiCenter Study of Combined PEX, Rituximab, and Steroids in Acute Idiopathic Pulmonary Fibrosis Exacerbations [Phase 2]
A Phase 2 trial evaluating plasmapheresis, rituximab, and steroids for acute idiopathic pulmonary fibrosis exacerbations has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-12-29Clinical Trial Update: A Study to Evaluate the Potential Role of Mesenchymal Stem Cells in the Treatment of Idiopathic Pulmonary Fibrosis [Phase 1]
Phase 1 clinical trial evaluating mesenchymal stem cells for idiopathic pulmonary fibrosis; trial completed and results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-12-28Clinical Trial Update: A Study to Evaluate the Safety and Effectiveness of CNTO 888 Administered Intravenously (IV) in Participants With Idiopathic Pulmonary Fibrosis (IPF) [Phase 2]
A Phase 2 study evaluated the safety and effectiveness of CNTO 888 administered intravenously in participants with idiopathic pulmonary fibr…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis [Phase 2]
This clinical trial update reports the completion of Phase 2 testing of zileuton for idiopathic pulmonary fibrosis.
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: Microaspiration in Pulmonary Fibrosis
The UCSF-sponsored clinical trial on microaspiration in idiopathic pulmonary fibrosis has completed.
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CLINICAL_TRIALS withdrawal · 2015-11-30Clinical Trial Update: Determining in Vitro Properties of Epithelial Cells From Individuals With Genetic Variants Associated With Idiopathic Pulmonary Fibrosis
The clinical trial NCT02187393, sponsored by the University of Colorado, Denver, investigating epithelial cell properties in individuals wit…
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CLINICAL_TRIALS trial_result · 2015-10-27Clinical Trial Update: Reliability of the 4 Metre Gait Speed in Idiopathic Pulmonary Fibrosis
Completed clinical trial update evaluating the reliability of the 4-metre gait speed test in idiopathic pulmonary fibrosis patients.
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CLINICAL_TRIALS trial_result · 2015-09-03Clinical Trial Update: Effects of an Oxymizer® During Daytime in Patients With Pulmonary Fibrosis (IPF) [NA]
A completed clinical trial update examines the daytime use of the Oxymizer oxygen-conserving device in patients with idiopathic pulmonary fi…
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CLINICAL_TRIALS research · 2015-07-28Clinical Trial Update: Study of the Etiology and Immunological Pathogenesis in Acute Exacerbation of Idiopathic Pulmonary Fibrosis (AE-IPF)
Clinical trial update on the etiology and immunological pathogenesis of acute exacerbation in idiopathic pulmonary fibrosis.
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CLINICAL_TRIALS other · 2015-07-13Clinical Trial Update: Expanded Access Program (EAP): Allow Patients in the US With Idiopathic Pulmonary Fibrosis Access to Pirfenidone
The update announces an Expanded Access Program in the United States to allow patients with Idiopathic Pulmonary Fibrosis to access Pirfenid…
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CLINICAL_TRIALS trial_result · 2015-07-09Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of GS-6624 (Formerly AB0024) in Patients With Idiopathic Pulmonary Fibrosis [Phase 1]
A Phase 1 study evaluating safety and efficacy of GS-6624 (formerly AB0024) in idiopathic pulmonary fibrosis has completed. The trial sponso…
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CLINICAL_TRIALS research · 2015-06-30Clinical Trial Update: Study of Default Options in Advance Directives [NA]
Status update on a completed clinical trial studying default options in advance directives, with enrollment across COPD, idiopathic pulmonar…
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CLINICAL_TRIALS trial_result · 2015-06-02Clinical Trial Update: Evaluating the Effectiveness of Prednisone, Azathioprine, and N-acetylcysteine in Patients With IPF [Phase 3]
Phase 3 trial evaluating prednisone, azathioprine, and N-acetylcysteine in idiopathic pulmonary fibrosis has completed. Results were posted …
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CLINICAL_TRIALS research · 2015-04-21Clinical Trial Update: Race, Ethnicity, and Diffuse Parenchymal Lung Disease
An update from Columbia University on race, ethnicity, and diffuse parenchymal lung disease, focusing on idiopathic pulmonary fibrosis and i…
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CLINICAL_TRIALS trial_result · 2015-04-13Clinical Trial Update: Study of GC1008 in Patients With Idiopathic Pulmonary Fibrosis (IPF) [Phase 1]
This update reports the completion of a Phase 1 study of GC1008 (fresolimumab) in patients with Idiopathic Pulmonary Fibrosis.
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CLINICAL_TRIALS trial_result · 2015-04-10Clinical Trial Update: Conducting Airways in Lung Fibrosis (VACFI)
A completed clinical trial (NCT01777373) investigating conducting airways in idiopathic pulmonary fibrosis, sponsored by Assistance Publique…
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CLINICAL_TRIALS research · 2015-04-09Clinical Trial Update: The Role of Rheumatological Evaluation in the Management of Patients With Interstitial Lung Disease
A clinical trial update examining how rheumatological evaluation may inform management of interstitial lung disease, including idiopathic pu…
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CLINICAL_TRIALS trial_result · 2015-03-12Clinical Trial Update: Efficacy and Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis (IPF) [Phase 3]
A Phase 3 trial update reports on the efficacy and safety of pirfenidone in idiopathic pulmonary fibrosis.
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: Study of the Effects of High-dose N-acetylcysteine (NAC) in Idiopathic Pulmonary Fibrosis (IPF) [Phase 3]
This document notes the completion of a Phase 3 study evaluating high-dose N-acetylcysteine in idiopathic pulmonary fibrosis, sponsored by Z…
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CLINICAL_TRIALS trial_result · 2015-02-13Clinical Trial Update: Safety and Efficacy of BIBF 1120 at High Dose in Idiopathic Pulmonary Fibrosis Patients [Phase 3]
A Phase 3 trial evaluated high-dose BIBF 1120 (nintedanib) in idiopathic pulmonary fibrosis and reported safety and efficacy results.