Idiopathic Pulmonary Fibrosis
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Herpesvirus in Idiopathic Pulmonary Fibrosis
This clinical trial update indicates that a study examining herpesvirus involvement in idiopathic pulmonary fibrosis has completed. The snip…
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CLINICAL_TRIALS other · 2017-05-08Clinical Trial Update: Expanded Access Program of Nintedanib in Patients With Idiopathic Pulmonary Fibrosis (EAP)
Expanded Access Program update for Nintedanib in idiopathic pulmonary fibrosis, noting that the therapy is approved for marketing.
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CLINICAL_TRIALS trial_result · 2017-05-01Clinical Trial Update: First Time in Human (FTIH) Study of GSK3008348 in Healthy Volunteers and Idiopathic Pulmonary Fibrosis Patients [Phase 1]
First-in-human Phase 1 study of GSK3008348 in healthy volunteers and idiopathic pulmonary fibrosis patients has been completed.
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CLINICAL_TRIALS withdrawal · 2017-04-28Clinical Trial Update: Evaluation of Patients With Idiopathic Pulmonary Fibrosis (IPF) Through an IPF Registry
The IPF registry trial NCT00212511 sponsored by NYU Langone Health has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Evaluation of Long-Term Safety of Pirfenidone (Esbriet) in Participants With Idiopathic Pulmonary Fibrosis (IPF)
The study provides long-term safety data for pirfenidone (Esbriet) in patients with idiopathic pulmonary fibrosis, reporting completed safet…
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CLINICAL_TRIALS research · 2017-04-19Clinical Trial Update: Controls for Respiratory Diseases
An ongoing Seoul National University Hospital study update on controls for respiratory diseases, including COPD and asthma, currently recrui…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Study to Assess the Efficacy and Safety of Simtuzumab (GS-6624) in Adults With Idiopathic Pulmonary Fibrosis (IPF) [Phase 2]
A Phase 2 study evaluating Simtuzumab (GS-6624) for idiopathic pulmonary fibrosis was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: 68Ga-BMV101 PET/CT in Patients With Idiopathic Pulmonary Fibrosis [EARLY_Phase 1]
This document updates on a Phase 1 trial evaluating 68Ga-BMV101 PET/CT in patients with Idiopathic Pulmonary Fibrosis.
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Long-Term Safety Study of GS-6624 in Adults With Idiopathic Pulmonary Fibrosis (IPF) [Phase 2]
A Phase 2 long-term safety study of GS-6624 in adults with idiopathic pulmonary fibrosis has been terminated, and results have been posted.
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Open-Label Study of the Long Term Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis (IPF) [Phase 3]
Open-label long-term safety study of pirfenidone in idiopathic pulmonary fibrosis; results from a Phase 3 trial have been posted.
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Pulmonary Rehabilitation for Idiopathic Pulmonary Fibrosis [NA]
This entry reports on the completion of a clinical trial investigating pulmonary rehabilitation for idiopathic pulmonary fibrosis.
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: A Study to Assess the Tolerability of a Single Dose of Gefapixant (AF-219/MK-7264) in Subjects With Idiopathic Pulmonary Fibrosis (IPF) [Phase 2]
Phase 2 trial update on tolerability of a single dose of gefapixant (AF-219/MK-7264) in idiopathic pulmonary fibrosis completed with results…
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CLINICAL_TRIALS trial_result · 2017-03-06Clinical Trial Update: Safety and PK Study of BIBF 1120 in Japanese Patients With IPF: Follow up Study From 1199.31(NCT01136174) [Phase 2]
A Phase 2 safety and pharmacokinetics study of nintedanib (BIBF 1120) in Japanese patients with idiopathic pulmonary fibrosis; results have …
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CLINICAL_TRIALS research · 2017-03-06Clinical Trial Update: Nasal, Tracheal and Bronchial Mucosal Lining Fluid(MLF) Sampling From Patients With Respiratory Diseases
This clinical trial update describes sampling of nasal, tracheal, and bronchial mucosal lining fluid from patients with various respiratory …
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: Clinical Progression of Mild to Moderate Idiopathic Pulmonary Fibrosis (IPF) Under a Therapy With Esbriet® (Pirfenidone)
An update on a clinical trial examining progression of mild to moderate idiopathic pulmonary fibrosis in patients treated with pirfenidone (…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: The Occurence of Inflammation and Oxidative Stress in Lung Diseases
A completed clinical trial evaluated the occurrence of inflammation and oxidative stress in multiple lung diseases. The conditions studied i…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: D2212C00002 J-Phase II Study [Phase 2]
AstraZeneca's Phase II J-Phase study D2212C00002 for idiopathic pulmonary fibrosis has completed, with results posted in 2017.
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FDA approval · 2017-01-11FDA Approved: ESBRIET — Original Application (Genentech, Inc.)
FDA approves Esbriet (pirfenidone) from Genentech in an Original Application for the treatment of idiopathic pulmonary fibrosis.
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CLINICAL_TRIALS trial_result · 2016-12-23Clinical Trial Update: The Effect of Pirfenidone on Cough in Patients With Idiopathic Pulmonary Fibrosis
This clinical trial update reports that a study evaluating the effect of pirfenidone on cough in idiopathic pulmonary fibrosis has completed…
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CLINICAL_TRIALS withdrawal · 2016-11-02Clinical Trial Update: A Study of Oral Vismodegib for the Treatment of Idiopathic Pulmonary Fibrosis (IPF) [Phase 2]
A Phase 2 clinical trial evaluating oral vismodegib for idiopathic pulmonary fibrosis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-09-19Clinical Trial Update: Study in Subjects With PAH and PH Secondary to IPF Using Inhaled GeNOsyl. [Phase 2]
Phase 2 study of inhaled GeNOsyl for pulmonary arterial hypertension and pulmonary hypertension due to idiopathic pulmonary fibrosis has com…
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CLINICAL_TRIALS research · 2016-09-01Clinical Trial Update: The Coagulation Cascade in Idiopathic Pulmonary Fibrosis [NA]
This entry reports an update on a clinical trial exploring how the coagulation cascade may relate to idiopathic pulmonary fibrosis (IPF).
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CLINICAL_TRIALS trial_result · 2016-07-29Clinical Trial Update: Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension [Phase 2]
Phase 2 trial evaluating sildenafil to increase exercise capacity in idiopathic pulmonary fibrosis with pulmonary hypertension has completed…
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Idiopathic Pulmonary Fibrosis--Pathogenesis and Staging - SCOR in Occupational and Immunological Lung Diseases
This clinical trial update covers idiopathic pulmonary fibrosis, focusing on pathogenesis and staging within the SCOR framework for occupati…
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CLINICAL_TRIALS trial_result · 2016-07-01Clinical Trial Update: Exhaled Breath Condensate Biomarkers and Cough in IPF
This update summarizes findings from a completed trial investigating exhaled breath condensate biomarkers and cough in idiopathic pulmonary …