Idiopathic Pulmonary Arterial Hypertension
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals
This ClinicalTrials.gov update describes a recruiting study at Vanderbilt University Medical Center investigating risk and resilience in ind…
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: 129 Xenon MRI as a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH) [Phase 2]
Phase 2 clinical trial examining Xenon-129 MRI as a biomarker for diagnosis and treatment response in pulmonary arterial hypertension, curre…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Cardiac Assessment by PV Loop in IPAH and Scleroderma PAH
Johns Hopkins University conducted a clinical trial using PV loop cardiac assessment in patients with idiopathic pulmonary arterial hyperten…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Hormonal, Metabolic, and Signaling Interactions in PAH
A Vanderbilt University Medical Center study investigating hormonal, metabolic, and signaling interactions in pulmonary arterial hypertensio…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Pulmonary Hypertension Biorepository and Registry
A pulmonary hypertension biorepository and registry sponsored by the University of Kansas Medical Center is actively recruiting (NCT04808596…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Right Ventricle Lipid in Pulmonary Arterial Hypertension (PAH)
A Vanderbilt-led clinical trial is investigating lipids in the right ventricle of patients with pulmonary arterial hypertension, including i…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Empagliflozin in Pulmonary Arterial Hypertension [Phase 2]
A Phase 2 clinical trial evaluating empagliflozin for idiopathic pulmonary arterial hypertension has completed.
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: FreeFlow Percutaneous Atrial Septal Shunt for IPAH [NA]
A clinical trial update shows recruitment is ongoing for the FreeFlow Percutaneous Atrial Septal Shunt in patients with idiopathic pulmonary…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Features of the Clinical Course and Prognosis in Patients With Idiopathic Pulmonary Hypertension When Using Modern Strategies of Specific Therapy
A clinical trial update examining the clinical course and prognosis of idiopathic pulmonary arterial hypertension patients treated with mode…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Spironolactone Therapy in Chronic Stable Right HF Trial [Phase 4]
A Phase 4 clinical trial assessing spironolactone therapy in patients with chronic stable right heart failure, including those with pulmonar…
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CLINICAL_TRIALS trial_result · 2021-06-24Clinical Trial Update: A Mobile Health Intervention in Pulmonary Arterial Hypertension [NA]
Clinical trial update for a mobile health intervention in pulmonary arterial hypertension; study completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2018-07-11Clinical Trial Update: The Exercise Capacity and Quality of Life in the Patients With IPAH and Secondary PH
A completed clinical trial evaluating exercise capacity and quality of life in patients with idiopathic pulmonary arterial hypertension and …
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CLINICAL_TRIALS trial_result · 2016-12-23Clinical Trial Update: Acute Effects of Benzbromaron on the Pulmonary Circulation [Phase 2]
Phase 2 clinical trial evaluating the acute effects of benzbromarone on the pulmonary circulation in idiopathic pulmonary arterial hypertens…
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CLINICAL_TRIALS research · 2016-11-09Clinical Trial Update: Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies
This entry provides an update on a mechanistic study investigating the physiopathology of idiopathic pulmonary arterial hypertension conduct…
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CLINICAL_TRIALS research · 2016-04-11Clinical Trial Update: Prospective Longitudinal Study of Patients With Idiopathic Pulmonary Arterial Hypertension, Family or Taking Anorectics [NA]
A completed prospective longitudinal study of patients with idiopathic pulmonary arterial hypertension, including individuals with a family …
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CLINICAL_TRIALS research · 2016-02-02Clinical Trial Update: Genetic and Environmental Characteristics of Primary Pulmonary Hypertension
A completed Vanderbilt University study evaluating genetic and environmental factors in idiopathic pulmonary arterial hypertension and descr…
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CLINICAL_TRIALS withdrawal · 2015-12-30Clinical Trial Update: Albuterol and Dynamic Hyperinflation in Idiopathic Pulmonary Arterial Hypertension [Phase 2]
A Phase 2 trial evaluating albuterol for dynamic hyperinflation in idiopathic pulmonary arterial hypertension has been withdrawn.
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CLINICAL_TRIALS research · 2015-03-31Clinical Trial Update: Catheter Denervation of Pulmonary Arteries in Treatment of IPAH & SPAH [Phase 1]
Phase 1 clinical trial investigating catheter-based denervation of the pulmonary arteries as a treatment for idiopathic and secondary pulmon…
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CLINICAL_TRIALS other · 2014-01-14Clinical Trial Update: Beta-blockers in i-PAH [Phase 1, Phase 2]
An update on a Phase 1/2 trial evaluating beta-blockers for Idiopathic Pulmonary Arterial Hypertension; the current status of the study is u…
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CLINICAL_TRIALS research · 2013-08-12Clinical Trial Update: Exercise Capacity and Quality of Life in Patients With PPH Receiving Short Term Oral L-Citrulline Malate [EARLY_Phase 1]
Clinical trial investigating the effects of short-term oral L-citrulline malate on exercise capacity and quality of life in patients with id…
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CLINICAL_TRIALS trial_result · 2012-08-21Clinical Trial Update: Combination Therapy of Bosentan and Aerosolized Iloprost in Idiopathic Pulmonary Arterial Hypertension (IPAH) [Phase 4]
This Phase 4 clinical trial evaluating the combination of bosentan and inhaled iloprost for idiopathic pulmonary arterial hypertension has b…
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CLINICAL_TRIALS trial_result · 2011-02-02Clinical Trial Update: Iron Deficiency In Pulmonary Hypertension [Phase 4]
This is a Phase 4 clinical trial update examining iron deficiency in idiopathic pulmonary arterial hypertension.
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CLINICAL_TRIALS trial_result · 2010-09-16Clinical Trial Update: Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing [Phase 3]
Phase 3 clinical trial comparing inhaled nitric oxide versus oxygen in acute vasodilator testing for participants with pulmonary vascular co…
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CLINICAL_TRIALS trial_result · 2008-03-24Clinical Trial Update: Safety and Feasibility of Autologous Endothelial Progenitor Cells Transplantation in Patients With Idiopathic Pulmonary Arterial Hypertension [NA]
A completed clinical trial evaluating the safety and feasibility of autologous endothelial progenitor cell transplantation in patients with …
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CLINICAL_TRIALS trial_result · 2006-09-06Clinical Trial Update: Safety and Efficacy Study of Transplantation of EPCs to Treat Idiopathic Pulmonary Arterial Hypertension [NA]
This document reports a safety and efficacy study evaluating transplantation of endothelial progenitor cells (EPCs) to treat idiopathic pulm…