Idiopathic Parkinson Disease
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Prolactin, Inflammation, and Parkinson's Severity
An ongoing invitation-only trial from Çanakkale Onsekiz Mart University is examining the relationship between prolactin, inflammation, and P…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Infusion of Apomorphine: Long-term Safety Study [Phase 3]
This is a Phase 3 long-term safety study evaluating infusion of apomorphine in idiopathic Parkinson's disease. The trial is currently active…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Effects of Sensory-Motor Integration Training in Patients with Idiopathic Parkinson's Disease [NA]
A completed clinical trial from Hacettepe University studied the effects of sensory-motor integration training in patients with Idiopathic P…
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CLINICAL_TRIALS trial_result · 2023-01-26Clinical Trial Update: Adipose-derived Stromal Vascular Fraction Cells to Treat Parkinson [Phase 1, Phase 2]
Clinical trial update for adipose-derived stromal vascular fraction cells in Parkinson's disease (Phase 1/Phase 2; completed).
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CLINICAL_TRIALS trial_result · 2022-09-26Clinical Trial Update: Lundbeck TOMs Orthostatic Hypotension [Phase 4]
A Phase 4 trial update for Lundbeck TOMs addressing orthostatic hypotension in patients with idiopathic Parkinson disease; study completed w…
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CLINICAL_TRIALS trial_result · 2020-07-10Clinical Trial Update: Evaluation of Safety and Tolerability of Fetal Mesencephalic Dopamine Neuronal Precursor Cells for Parkinson's Disease [Phase 1, Phase 2]
Clinical trial update on safety and tolerability of fetal mesencephalic dopamine neuronal precursor cells for Parkinson's disease (Phase 1/P…
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CLINICAL_TRIALS trial_result · 2019-12-13Clinical Trial Update: Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease [Phase 3]
This entry reports the completion of a Phase 3 long-term study of istradefylline in moderate to severe Parkinson's disease, with results pos…
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CLINICAL_TRIALS research · 2019-10-29Clinical Trial Update: Pharmacokinetics and Pharmacodynamics of IPX054 in Subjects With Parkinson's Disease [Phase 1, Phase 2]
A clinical trial update reports pharmacokinetics and pharmacodynamics data for IPX054 in subjects with idiopathic Parkinson's disease from P…
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CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: Comparison of IPX054, IR Carbidopa-Levodopa, and CR Carbidopa-Levodopa in Subjects With Parkinson's Disease [Phase 2]
Phase 2 trial comparing IPX054 with immediate-release and controlled-release carbidopa-levodopa in Parkinson's disease completed.
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CLINICAL_TRIALS trial_result · 2019-03-26Clinical Trial Update: Safety and Efficacy Study of Tozadenant to Treat End of Dose Wearing Off in Parkinson's Patients [Phase 3]
Phase 3 safety and efficacy study of Tozadenant for end of dose wearing off in Parkinson's disease was terminated, with results posted in 20…
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: Randomized Safety Study of CVT-301 Compared to an Observational Control Group [Phase 3]
A completed Phase 3 randomized safety study comparing CVT-301 to an observational control in idiopathic Parkinson's disease with results pos…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Efficacy and Safety Study of CVT-301 In Parkinson's Disease Patients With OFF Episodes [Phase 3]
Phase 3 clinical trial update on CVT-301 in Parkinson's disease patients with OFF episodes reports efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2017-08-07Clinical Trial Update: PF-06669571 In Subjects With Idiopathic Parkinson's Disease [Phase 1]
Phase 1 trial update for PF-06669571 in idiopathic Parkinson's disease; study completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2016-04-12Clinical Trial Update: Placebo Controlled Study of Preladenant in Participants With Moderate to Severe Parkinson's Disease (P07037) [Phase 3]
Phase 3 trial of preladenant in moderate to severe Parkinson's disease completed; results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: Rotigotine Versus Placebo, A Study To Evaluate The Efficacy In Advanced Stage Idiopathic Parkinson's Disease Patients [Phase 3]
A Phase 3 randomized trial evaluated rotigotine versus placebo for efficacy in advanced-stage idiopathic Parkinson's disease. The study is c…
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CLINICAL_TRIALS research · 2015-12-02Clinical Trial Update: Vascular Abnormalities in Idiopathic Parkinson's Disease
A clinical trial update focusing on vascular abnormalities in idiopathic Parkinson's disease; the current status is unknown.
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CLINICAL_TRIALS trial_result · 2015-09-09Clinical Trial Update: Efficacy of Acupuncture and Bee Venom Acupuncture on Patients With Idiopathic Parkinson's Disease [NA]
A completed clinical trial evaluated the efficacy of acupuncture and bee venom acupuncture in patients with idiopathic Parkinson's disease.
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CLINICAL_TRIALS trial_result · 2015-05-29Clinical Trial Update: Walking Capacity in Parkinson's Disease (PD-Walk) [NA]
A clinical trial studying walking capacity in idiopathic Parkinson's disease has been terminated.
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CLINICAL_TRIALS trial_result · 2015-01-19Clinical Trial Update: Trial to Evaluate The Efficacy Of Rotigotine on Parkinson's Disease-Associated Motor Symptoms And Apathy [Phase 4]
Phase 4 trial assessing the efficacy of rotigotine on motor symptoms and apathy in Parkinson's disease has completed with posted results.
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: Placebo-controlled Study in Patients With Parkinson's Disease to Evaluate the Effect of Rotigotine on Non-motor Symptoms [Phase 4]
A placebo-controlled Phase 4 trial evaluating rotigotine for non-motor symptoms in idiopathic Parkinson's disease has completed, with result…
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CLINICAL_TRIALS trial_result · 2013-10-29Clinical Trial Update: MOTION, Safinamide in Early IPD, as add-on to Dopamine Agonist [Phase 3]
Phase 3 MOTION trial of safinamide as add-on to dopamine agonist in early idiopathic Parkinson's disease has been completed.
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CLINICAL_TRIALS trial_result · 2013-04-23Clinical Trial Update: Change in Gastrointestinal Complaints After Switch From Oral Parkinson's Disease Treatment to Neupro® Transdermal Patch
A clinical trial update reports changes in gastrointestinal complaints after switching from an oral Parkinson's disease treatment to the rot…
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CLINICAL_TRIALS trial_result · 2013-03-29Clinical Trial Update: Safinamide in Idiopathic Parkinson's Disease (IPD) With Motor Fluctuations, as add-on to Levodopa [Phase 3]
Phase 3 trial evaluating safinamide as add-on therapy to levodopa in idiopathic Parkinson's disease with motor fluctuations has completed.
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CLINICAL_TRIALS trial_result · 2013-03-29Clinical Trial Update: A Study to Assess the Effect of Safinamide on Levodopa Pharmacokinetics [Phase 1, Phase 2]
A Phase 1/2 study evaluated the effect of safinamide on levodopa pharmacokinetics in idiopathic Parkinson's disease; the trial has completed…
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CLINICAL_TRIALS research · 2010-02-19Clinical Trial Update: A Multi-Center, Observational Safety Registry of Subjects With Idiopathic Parkinson's Disease Previously Treated With Intraputaminal Infusion of Liatermin
This entry notes the completion of a multi-center observational safety registry evaluating Parkinson's disease patients who were previously …