Idiopathic Inflammatory Myopathy
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy [Phase 2, Phase 3]
An open-label Phase 2/3 trial to evaluate the safety and efficacy of CABA-201 in active idiopathic inflammatory myopathy and related juvenil…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy [Phase 3]
A Phase 3 trial evaluating the long-term safety and efficacy of a subcutaneous formulation of efgartigimod in adults with active idiopathic …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic Autoimmune Rheumatic Diseases [Phase 1]
Phase 1 clinical trial evaluating the safety of CD19-targeted CAR-T cell therapy produced at Gustave Roussy for adults with severe and refra…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of BEN301 Injection in the Treatment of Autoimmune Diseases [EARLY_Phase 1]
Early Phase 1 clinical trial update for BEN301 injection evaluating safety in autoimmune diseases including systemic sclerosis, rheumatoid a…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease [Phase 1]
Phase 1 clinical trial update for ALLO-329, an allogeneic CAR T-cell therapy, in adults with autoimmune diseases including systemic lupus er…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of KITE-363 in Participants With Refractory Autoimmune Diseases [Phase 1]
Phase 1 study evaluating KITE-363 in participants with refractory autoimmune diseases, currently enrolling by invitation, including systemic…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Safety and Efficacy of ULSC on Disease Severity and Steroid Tapering in Participants With Dermatomyositis/ Polymyositis (DM/PM), Also Known as Idiopathic Inflammatory Myopathy (IIM) [Phase 2, Phase 3]
The sponsor reports an ongoing Phase 2/3 trial assessing the safety and efficacy of ULSC in reducing disease severity and aiding steroid tap…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Allogeneic CD19/BCMA-Targeted CAR-γδT Cell Therapy: Safety and Preliminary Pharmacodynamics in Relapsed/Refractory Autoimmune Diseases [Phase 1]
Phase 1 clinical trial update on an allogeneic CD19/BCMA-targeted CAR-γδT cell therapy assessing safety and preliminary pharmacodynamics in …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Add-on Intravenous Immunoglobulins in Early Myositis [Phase 2, Phase 3]
A Phase 2/Phase 3 add-on intravenous immunoglobulin study for early inflammatory myopathies (myositis) is active but not currently recruitin…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Clinical Study on Targeted CD19/BCMA CAR-T Therapy for Autoimmune Diseases [EARLY_Phase 1]
Early-phase clinical study of a targeted CD19/BCMA CAR-T therapy for autoimmune diseases is recruiting, including systemic lupus erythematos…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: IMPT-514 in Systemic Lupus Erythematosus, Anca-associated Vasculitis, and Idiopathic Inflammatory Myopathy [EARLY_Phase 1]
An early-phase 1 clinical trial of IMPT-514 in systemic lupus erythematosus, ANCA-associated vasculitis, and idiopathic inflammatory myopath…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: GC012F Injection in Refractory Idiopathic Inflammatory Myopathy [EARLY_Phase 1]
An early-phase clinical trial update indicates GC012F injection is being evaluated for refractory idiopathic inflammatory myopathy and is cu…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases [NA]
This clinical trial is recruiting to evaluate anti-CD19 IL-10/IL-15 CAR-NK cells for refractory/relapsed autoimmune diseases. Conditions inc…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases. [Phase 2]
Phase 2 trial evaluating AlloNK, an allogeneic cord blood-derived NK cell therapy, in combination with Rituximab for relapsing B-cell–depend…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases. [EARLY_Phase 1]
Phase 1 study evaluating anti-CD19/BCMA universal CAR-T cell therapy RD06-05 in autoimmune diseases; the trial is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases [Phase 1]
Phase 1 clinical trial of HBI0101 CAR-T therapy for refractory B-cell autoimmune diseases (SLE, systemic sclerosis, idiopathic inflammatory …
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: GC012F in Patients With Autoimmune Diseases [EARLY_Phase 1]
This early-phase trial update reports on GC012F being studied for autoimmune diseases (systemic sclerosis and idiopathic inflammatory myopat…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Clinical Study on the Targeted CD19 Universal CAR-T Cell Injection (RD06-04) for the Treatment of IIM and AAV [EARLY_Phase 1]
This update covers an early-phase Phase 1 trial of RD06-04, a targeted CD19 universal CAR-T cell therapy, for idiopathic inflammatory myopat…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: A Study of OL-108 in Relapsed/Refractory Autoimmune Diseases [Phase 1]
A Phase 1 study evaluating OL-108 in relapsed/refractory autoimmune diseases is currently recruiting, including systemic lupus erythematosus…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Follow-up of Patients With Inflammatory Myopathies Associated With a Biobank
Clinical trial update noting ongoing recruitment for a biobank–associated study of inflammatory myopathies, including idiopathic inflammator…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: MYOPROSP - a Prospective Cohort Study in Myositis
Clinical trial update for MYOPROSP, a prospective cohort study in myositis, currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Renal Manifestations During Idiopathic Inflammatory Myopathies
A recruiting clinical trial at University Hospital, Strasbourg, France is investigating renal manifestations in patients with idiopathic inf…
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CLINICAL_TRIALS research · 2024-05-22Clinical Trial Update: Clinical Database and Biobank of Patients With Inflammatory Myopathies: the MASC Project (Myositis, DNA, Serum, Cells) (MASC)
The MASC Project is a clinical database and biobank collecting DNA, serum, cells, and clinical data from patients with inflammatory myopathi…