Hypoxic-ischemic Encephalopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Cracking Coma: Towards EEG and MRI Based Precision Medicine After Cardiac Arrest
This clinical trial update reports the completion of the Cracking Coma study, which investigates EEG- and MRI-based precision medicine appro…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Measuring Heart Health in Both Term, Preterm and Unwell Newborn Babies With an Advanced Ultrasound Method: Speckle Tracking Echocardiography
A clinical trial update describing the use of speckle tracking echocardiography to measure heart health in term, preterm, and unwell newborn…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Expanded Access Protocol: Umbilical Cord Blood Infusions for Children With Brain Injuries
Expanded Access Protocol update for Umbilical Cord Blood Infusions in children with brain injuries; sponsor listed as Joanne Kurtzberg, MD, …
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy for the Treatment of Traumatic Brain Injury and Hypoxic-Ischemic Encephalopathy [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating autologous mesenchymal stem cell therapy for traumatic brain injury and hypoxic-ischemic encephalopath…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Assess Safety and Efficacy of Sovateltide in Hypoxic-ischemic Encephalopathy [Phase 2]
Phase 2 study evaluating safety and efficacy of Sovateltide in neonates with Hypoxic-Ischemic Encephalopathy; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Transauricular Vagus Nerve Stimulation in Children [NA]
An ongoing pediatric trial evaluating transauricular vagus nerve stimulation for hypoxic-ischemic encephalopathy; enrollment is by invitatio…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: A Study of a Blood Marker in Newborns With Brain Injury Caused by Lack of Oxygen at Birth
This clinical trial update reports on evaluating a blood biomarker in newborns with brain injury due to hypoxic-ischemic encephalopathy; the…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Treatment of Seizures in Neonate With HIE [Phase 4]
Phase 4 clinical trial update on treating seizures in neonates with hypoxic-ischemic encephalopathy; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia
A clinical trial update describes research using near-infrared spectroscopy (NIRS) to optimize therapeutic hypothermia for perinatal brain i…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Evaluation of Haemodynamic in Neonates Treated With Hypothermia"
Completed clinical trial update evaluating haemodynamics in neonates treated with therapeutic hypothermia for perinatal asphyxia.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Efficacy of Erythropoietin to Improve Survival and Neurological Outcome in Hypoxic Ischemic Encephalopathy [Phase 3]
This Phase 3 trial evaluated whether erythropoietin improves survival and neurological outcomes in hypoxic ischemic encephalopathy. The stud…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Mesenchymal Stem Cells With Cooling Therapy for Infants With Hypoxic-Ischemic Encephalopathy [Phase 1, Phase 2]
A Phase 1/2 clinical trial at Mahidol University is evaluating mesenchymal stem cells combined with cooling therapy for neonatal hypoxic-isc…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures [Phase 2]
This document describes a Phase 2 dose-escalation trial of levetiracetam for neonatal seizures that is currently ongoing. The study is recru…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia [EARLY_Phase 1]
An early-phase 1 trial evaluating melatonin as a neuroprotective therapy in neonates with hypoxic ischemic encephalopathy undergoing therape…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: The HIEnome Study: Genome Sequencing for Perinatal HIE [NA]
This clinical trial update describes the HIEnome Study, which uses genome sequencing to study perinatal hypoxic-ischemic encephalopathy and …
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Prognostic Factors to Regain Consciousness
A clinical trial is recruiting to identify prognostic factors for regaining consciousness in patients with neurologic disorders, including t…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Speech of Kids After Neonatal Encephalopathy
A clinical trial currently recruiting to evaluate speech and language development in children after neonatal hypoxic-ischemic encephalopathy…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Spinal Stimulation and Mobility Devices [NA]
A University of Washington clinical trial is currently recruiting to evaluate spinal stimulation and mobility devices for cerebral palsy and…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Nephroprotection Following Perinatal Asphyxia: Randomized Controlled Trial [NA]
This clinical trial update describes a randomized controlled study on nephroprotection after perinatal asphyxia in neonates with hypoxic-isc…
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CLINICAL_TRIALS withdrawal · 2025-07-22Clinical Trial Update: Cell-Based Therapy for White Matter Repair in Periventricular Leukomalacia [EARLY_Phase 1]
An early-phase cell-based therapy trial for white matter repair in periventricular leukomalacia has been withdrawn.
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)
This study from MaineHealth is investigating the immunoinflammatory response in post-cardiac arrest syndrome and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries Developmental Follow Up [NA]
A clinical trial update announcing ongoing recruitment for a study evaluating delivery-room cord milking and its developmental outcomes in l…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Predicting Mortality in Patients With Return of Spontaneous Circulation After Cardiac Arrest
This clinical trial update describes a study aimed at predicting mortality in patients with return of spontaneous circulation after cardiac …
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Severity of Hypoxic Ischemic Encephalopathy and Neurological Pupil Index in Neonates
A clinical trial from the University of Calgary studying the severity of hypoxic-ischemic encephalopathy and neurological pupil index in neo…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Feasibility and Safety of Intranasally Administered Breast Milk in HIE [EARLY_Phase 1]
Phase 1 study evaluating feasibility and safety of intranasal breast milk for neonatal hypoxic-ischemic encephalopathy; currently recruiting…