Hypoxic-ischemic Encephalopathy
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Autologous Bone Marrow Mononuclear Cell Transplantation Combined With Rehabilitation in Children With Sequelae of Hypoxic-Ischemic Encephalopathy or Intracranial Hemorrhage [NA]
This clinical trial is evaluating autologous bone marrow mononuclear cell transplantation combined with rehabilitation in children with sequ…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage [Phase 1, Phase 2]
This update reports a Phase 1/2 clinical trial testing theophylline given during therapeutic hypothermia to reduce neonatal kidney injury in…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: The Effect of Maternal Scent and Knitted Octopus Application on Pain in Infants Diagnosed With Neonatal Asphyxia and Receiving Therapeutic Hypothermia Treatment [NA]
The trial evaluating maternal scent and knitted octopus therapy for pain in infants with hypoxic-ischemic encephalopathy undergoing therapeu…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia [Phase 2]
A Phase 2 clinical trial evaluating safety, tolerability, pharmacokinetics, and preliminary efficacy of RLS-0071 in newborns with moderate o…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Real World Outcomes of Intranasal MuSE Exosomes and Stem Cells in Neurological Regenerative Therapy
An update on an ongoing real-world study of intranasal MuSE exosomes and stem cells for neurological regenerative therapy, with enrollment b…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: The PROTECT-HIE Pilot Trial [Phase 2]
A Phase 2 pilot clinical trial called PROTECT-HIE for hypoxic-ischemic encephalopathy is currently listed as not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Dose Optimization of Caffeine for HIE [Phase 1]
Phase 1 trial update exploring dose optimization of caffeine citrate for Hypoxic-Ischemic Encephalopathy. Recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: An Observational Study of the NeuroBell EEG Monitor
The study reports completion of an observational evaluation of the NeuroBell EEG Monitor in neonatal patients with seizures and related neur…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Sildenafil Plus Hypothermia to Treat Neonatal Encephalopathy [Phase 2]
Clinical trial update for a Phase 2 study of sildenafil plus therapeutic hypothermia to treat neonatal hypoxic-ischemic encephalopathy.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: New Tools and Predictive Markers in the Prognosis of Hypoxic-ischemic Encephalopathy Following Cardiac Arrest [NA]
Clinical trial update describing new tools and predictive biomarkers to aid prognosis in patients with hypoxic-ischemic encephalopathy after…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Healing Tiny Minds: Rural Recovery Through Virtual and Lived Experience Care [NA]
A clinical trial update from the University of Wisconsin–Madison about Healing Tiny Minds, a study on rural recovery using virtual and lived…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
Clinical trial update on an intensive multimodal neurorehabilitation program aimed at enhancing neuroplasticity in pediatric neurodevelopmen…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
Clinical trial update on intranasal AAV9-PHP.eB gene therapy being studied for cerebral palsy and hypoxic ischemic encephalopathy, currently…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Investigating Cerebral Oxygenation in the Newborn
A University of Edinburgh study is investigating cerebral oxygenation in newborns with hypoxic-ischemic encephalopathy and neonatal encephal…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Genetics of Neonatal Encephalopathy and Related Disorders
A genetics-focused clinical trial at Boston Children's Hospital is studying the genetics of neonatal encephalopathy and related disorders an…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Early Detection of Brain Injury After Congenital Heart Surgery in Infants
This clinical trial is evaluating early detection of brain injury in infants after congenital heart surgery and is currently enrolling by in…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial) [Phase 2]
A Phase 2 trial (DICE) evaluating dexmedetomidine for pain management during therapeutic cooling in infants with neonatal hypoxic-ischemic e…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury [Phase 1]
A Phase 1 safety and feasibility protocol study evaluating the use of metformin in infants after perinatal brain injury, specifically hypoxi…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Biomarkers Study in Infants With Prior Neonatal Brain Injury
A biomarker study in infants with prior neonatal brain injury is currently recruiting, focusing on those with hypoxic-ischemic encephalopath…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Hydrogen In Neonatal Encephalopathy (HIE) Trial [Phase 1]
Phase 1 clinical trial assessing hydrogen therapy for neonatal hypoxic-ischemic encephalopathy is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries [NA]
ClinicalTrials.gov entry provides an update on a trial comparing delivery-room cord milking in low-resource countries, focusing on newborns …
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Florida Neonatal Neurologic Network
A ClinicalTrials.gov update shows the University of Florida-led Florida Neonatal Neurologic Network trial in neonates with Hypoxic-Ischemic …
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Predictive Value of aEEG and Cerebral Oxygenation on Neurological Outcomes in Newborns With Mild Hypoxic-Ischemic Encephalopathy
This clinical trial investigates whether aEEG and cerebral oxygenation measurements can predict neurological outcomes in newborns with mild …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Neonatal Seizure Registry - Developmental Functional EValuation
This clinical trial update reports the completion of the Neonatal Seizure Registry evaluating developmental functional outcomes in infants w…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy
A clinical trial registry entry from University of California, San Francisco describing a Neonatal Seizure Registry and Genetics of Post-Neo…