Hypoxic-ischemic Encephalopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: The Effect of Maternal Scent and Knitted Octopus Application on Pain in Infants Diagnosed With Neonatal Asphyxia and Receiving Therapeutic Hypothermia Treatment [NA]
The trial evaluating maternal scent and knitted octopus therapy for pain in infants with hypoxic-ischemic encephalopathy undergoing therapeu…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: An Observational Study of the NeuroBell EEG Monitor
The study reports completion of an observational evaluation of the NeuroBell EEG Monitor in neonatal patients with seizures and related neur…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial) [Phase 2]
A Phase 2 trial (DICE) evaluating dexmedetomidine for pain management during therapeutic cooling in infants with neonatal hypoxic-ischemic e…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Hydrogen In Neonatal Encephalopathy (HIE) Trial [Phase 1]
Phase 1 clinical trial assessing hydrogen therapy for neonatal hypoxic-ischemic encephalopathy is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: Cracking Coma: Towards EEG and MRI Based Precision Medicine After Cardiac Arrest
This clinical trial update reports the completion of the Cracking Coma study, which investigates EEG- and MRI-based precision medicine appro…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy for the Treatment of Traumatic Brain Injury and Hypoxic-Ischemic Encephalopathy [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating autologous mesenchymal stem cell therapy for traumatic brain injury and hypoxic-ischemic encephalopath…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Evaluation of Haemodynamic in Neonates Treated With Hypothermia"
Completed clinical trial update evaluating haemodynamics in neonates treated with therapeutic hypothermia for perinatal asphyxia.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Efficacy of Erythropoietin to Improve Survival and Neurological Outcome in Hypoxic Ischemic Encephalopathy [Phase 3]
This Phase 3 trial evaluated whether erythropoietin improves survival and neurological outcomes in hypoxic ischemic encephalopathy. The stud…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries Developmental Follow Up [NA]
A clinical trial update announcing ongoing recruitment for a study evaluating delivery-room cord milking and its developmental outcomes in l…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Dexmedetomidine Versus Morphine During Cooling Therapy in Neonates [Phase 2]
Phase 2 clinical trial comparing dexmedetomidine versus morphine during cooling therapy in neonates with hypoxic-ischemic injury; recruitmen…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: CEUS Evaluation of Hypoxic Ischemic Injury [Phase 3]
Phase 3 trial evaluating contrast-enhanced ultrasound (CEUS) for hypoxic-ischemic brain injury has completed and posted its results. Results…
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: Metabolic Monitoring During Therapeutic Hypothermia (Cooling) for Hypoxic Ischaemic Encephalopathy [NA]
The clinical trial update reports completion of a study evaluating metabolic monitoring during therapeutic hypothermia (cooling) for hypoxic…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Monitoring After Cardiac Arrest: Electroencephalogram and Cerebral Oximetry in Predicting Outcome
This completed clinical trial study evaluates whether electroencephalography (EEG) and cerebral oximetry can help predict outcomes after car…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Prospective Research in Infants With Mild Encephalopathy
This clinical trial update notes a completed prospective study in infants with mild encephalopathy due to hypoxic-ischemic events, with resu…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: ANS Function in HIE Infants Treated With Therapeutic Hypothermia
A completed clinical trial evaluated autonomic nervous system function in infants with hypoxic-ischemic encephalopathy treated with therapeu…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Hypothermia's Effect on Hepatitis B Vaccination
A completed clinical trial evaluating the impact of neonatal hypothermia on the immune response to the Hepatitis B vaccine.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Caffeine for Hypoxic-Ischemic Encephalopathy [Phase 1]
A Phase 1 clinical trial evaluating caffeine for hypoxic-ischemic encephalopathy has completed enrollment and posted results.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Therapeutic Intervention Supporting Development From NICU to 6 Months for Infants Post Hypoxic-Ischemic Encephalopathy [NA]
A completed USC-sponsored clinical trial evaluated a therapeutic intervention to support development from NICU to 6 months in infants after …
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Umbilical Cord Milking Versus Immediate Cord Clamping in Full Term Neonates (≥ 37 Weeks) Requiring Resuscitation [NA]
Completed clinical trial comparing Umbilical Cord Milking to Immediate Cord Clamping in full-term neonates needing resuscitation, assessing …
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic Encephalopathy [Phase 1, Phase 2]
A Phase 1/2 trial evaluated adding topiramate to whole-body cooling in neonates with hypoxic-ischemic encephalopathy; the study was terminat…
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CLINICAL_TRIALS trial_result · 2024-06-05Clinical Trial Update: PAEAN - Erythropoietin for Hypoxic Ischaemic Encephalopathy in Newborns [Phase 3]
This update reports the completion of a Phase 3 trial evaluating erythropoietin for hypoxic-ischemic encephalopathy in newborns.
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CLINICAL_TRIALS trial_result · 2024-04-22Clinical Trial Update: Preemie Hypothermia for Neonatal Encephalopathy [NA]
Clinical trial update indicates the preemie hypothermia trial for neonatal encephalopathy has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Magnesium Sulfate in Neonatal HIE" [Phase 4]
Phase 4 trial update on magnesium sulfate use in neonates with hypoxic-ischemic encephalopathy (HIE).
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CLINICAL_TRIALS trial_result · 2023-07-11Clinical Trial Update: Effect of Allopurinol for Hypoxic-ischemic Brain Injury on Neurocognitive Outcome [Phase 3]
Phase 3 trial evaluating allopurinol for neurocognitive outcomes after hypoxic-ischemic brain injury in newborns; status of the trial is cur…
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CLINICAL_TRIALS trial_result · 2023-05-03Clinical Trial Update: Hydrocortisone Therapy Optimization During Hypothermia Treatment in Asphyxiated Neonates [Phase 4]
A Phase 4 clinical trial assessing optimized hydrocortisone therapy during hypothermia in neonates with asphyxia and hypoxic-ischemic enceph…