Hypoplastic Left Heart Syndrome
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CLINICAL_TRIALS trial_result · 2020-06-04Clinical Trial Update: Oxygen Consumption-based Assessments of Hemodynamics in Neonates Following Congenital Heart Surgery (Oxy-CAHN Study) [NA]
A completed clinical trial evaluating oxygen consumption-based assessments of hemodynamics in neonates after congenital heart surgery, with …
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Ambrisentan in Single Ventricle [Phase 2]
A Phase 2 trial of ambrisentan in single-ventricle physiology (hypoplastic left/right heart complex) has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-08-02Clinical Trial Update: Prophylactic Peritoneal Dialysis Decreases Time to Achieve a Negative Fluid Balance After the Norwood Procedure [NA]
A completed clinical trial evaluating prophylactic peritoneal dialysis and its effect on time to achieve negative fluid balance after the No…
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CLINICAL_TRIALS withdrawal · 2018-05-01Clinical Trial Update: Positive Pressure Ventilation and Sternal Closure in HLHS
Clinical trial update shows the study evaluating positive pressure ventilation and sternal closure in Hypoplastic Left Heart Syndrome has be…
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: Evaluation of Panel Reactive Antibody in Children Following Stage I Palliation for Hypoplastic Left Heart Syndrome
A clinical trial evaluating panel reactive antibody in children after Stage I palliation for Hypoplastic Left Heart Syndrome has completed.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Impact of Vitamin C on Endothelial Function and Exercise Capacity in Fontan-Palliated Patients [NA]
Clinical trial update noting the completion of a study evaluating vitamin C on endothelial function and exercise capacity in Fontan-palliate…
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Impact of Early Intervention on Maternal Stress in Mothers of Fetuses Diagnosed With Single Ventricle Physiology [NA]
Clinical trial evaluating whether early intervention reduces maternal stress in pregnancies affected by single-ventricle congenital heart di…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Fluid Balance in Children Undergoing Fontan Surgery
This clinical trial update notes the completion of a study evaluating fluid balance in children undergoing Fontan surgery for congenital hea…
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CLINICAL_TRIALS trial_result · 2016-08-22Clinical Trial Update: Examining Developmental Changes in Heart Contractions of Children With Congenital Heart Defects
This clinical trial update reports that the study on developmental changes in heart contractions in children with congenital heart defects h…
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: Comparison of Feeding Strategies for Hypoplastic Left Heart Syndrome Infants [NA]
Clinical trial results compare feeding strategies for infants with Hypoplastic Left Heart Syndrome; results were posted in February 2016.
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: Transcoronary Infusion of Cardiac Progenitor Cells in Patients With Single Ventricle Physiology [Phase 1]
Phase 1 trial update on transcoronary infusion of cardiac progenitor cells in patients with single ventricle physiology, including hypoplast…
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CLINICAL_TRIALS trial_result · 2015-05-14Clinical Trial Update: Biomarker Study for Heart Failure in Children With Single Ventricle Physiology
This update reports the completion of a biomarker study assessing heart failure indicators in children with single-ventricle physiology, inc…
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CLINICAL_TRIALS trial_result · 2015-05-05Clinical Trial Update: Sildenafil After the Fontan Operation [Phase 2]
Phase 2 clinical trial evaluating sildenafil after the Fontan operation in children with Hypoplastic Left Heart Syndrome or Tricuspid Atresi…
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CLINICAL_TRIALS withdrawal · 2015-04-30Clinical Trial Update: Sleep Disordered Breathing in Children With Single Ventricle Physiology
The University of Rochester sponsored clinical trial evaluating sleep-disordered breathing in children with single-ventricle physiology, inc…
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CLINICAL_TRIALS trial_result · 2014-05-19Clinical Trial Update: Erythropoetin Neuroprotection for Neonatal Cardiac Surgery [Phase 1, Phase 2]
Clinical trial update on erythropoietin for neuroprotection in neonatal cardiac surgery (Phase 1/2) completed with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2013-12-12Clinical Trial Update: Single Ventricle Outcome
A clinical trial evaluating outcomes in single-ventricle congenital heart disease (including hypoplastic left heart syndrome) has completed.
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: Neurodevelopmental Outcomes in Hypoplastic Left Heart Syndrome
This update summarizes neurodevelopmental outcomes from a completed trial in patients with hypoplastic left heart syndrome.
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CLINICAL_TRIALS trial_result · 2013-04-19Clinical Trial Update: Study of Placebo or Bosentan to Treat Patients With Single Ventricle Physiology. [Phase 2]
This clinical trial update reports a Phase 2 study comparing placebo versus bosentan in patients with single ventricle physiology, including…
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CLINICAL_TRIALS trial_result · 2013-04-11Clinical Trial Update: Understanding Dexmedetomidine in Neonates After Open Heart Surgery [Phase 1]
Phase 1 trial evaluating dexmedetomidine for sedation in neonates after open-heart surgery; the study completed and results were posted in 2…
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CLINICAL_TRIALS trial_result · 2013-04-09Clinical Trial Update: Understanding Dexmedetomidine In Infants Post-Operative From Cardiac Surgery [Phase 1]
Phase 1 trial assessing the use of dexmedetomidine in infants after cardiac surgery has completed, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2012-11-14Clinical Trial Update: NIRS in Neonatal Cardiac Surgery
The clinical trial evaluating near-infrared spectroscopy (NIRS) monitoring during neonatal cardiac surgery for Hypoplastic Left Heart Syndro…
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CLINICAL_TRIALS trial_result · 2012-06-29Clinical Trial Update: Cerebral Perfusion During Neonatal Cardiac Surgery [NA]
A neonatal cerebral perfusion trial sponsored by UMC Utrecht has completed, studying patients with congenital heart defects including hypopl…
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CLINICAL_TRIALS trial_result · 2007-05-23Clinical Trial Update: Growth in Children With HLHS
This clinical trial update reports the termination of a study investigating growth in children with hypoplastic left heart syndrome.