Hypogonadotropic Hypogonadism
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CLINICAL_TRIALS trial_result · 2026-08-26Clinical Trial Results: Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism [Phase 2]
Phase 2 trial results evaluating prolonged pulsatile kisspeptin administration for hypogonadotropic hypogonadism.
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism [Phase 2]
Phase 2 trial evaluating prolonged pulsatile kisspeptin administration for hypogonadotropic hypogonadism has completed, with an update on st…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Opioid Antagonism in Hypogonadotropic Hypogonadism [Phase 1]
Phase 1 clinical trial evaluating opioid antagonism in hypogonadotropic hypogonadism has completed. The trial addresses low testosterone in …
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Kisspeptin Administration Subcutaneously to Patients With Reproductive Disorders [Phase 1]
Phase 1 trial evaluating subcutaneous kisspeptin in people with reproductive disorders; the study focusing on hypothalamic amenorrhea and hy…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism [Phase 4]
Phase 4 clinical trial update evaluating whether aromatase inhibitors promote weight loss in severely obese men with hypogonadotropic hypogo…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism [Phase 4]
Phase 4 trial assessing the effect of testosterone replacement therapy on blood pressure in adult male participants with hypogonadism; resul…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Product Transference Study of Testagen™ TDS®-Testosterone [Phase 2]
Phase 2 clinical trial update for Testagen TDS transdermal testosterone evaluating product transference. The study targets hypogonadotropic …
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Neuropeptides in Human Reproduction [Phase 1]
A Phase 1 trial conducted by Massachusetts General Hospital investigating neuropeptides in human reproduction for hypogonadotropic hypogonad…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Kisspeptin Administration in the Adult [Phase 1]
Phase 1 clinical trial evaluating Kisspeptin administration in adults with hypogonadotropic hypogonadism and related GnRH deficiencies, incl…
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CLINICAL_TRIALS trial_result · 2024-02-15Clinical Trial Update: A Randomized, Double-blinded, Clinical, Placebo-controlled Trial on the Effects of Therapy With Letrozole and hUman Choriongonadotropin in Male Hypogonadism Induced by Illicit Use of Anabolic Androgenic Steroids- The LUCAS Trial [Phase 4]
Phase 4 randomized trial assessing letrozole and hCG therapy for male hypogonadism induced by anabolic steroid use; the study status is term…
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CLINICAL_TRIALS trial_result · 2024-02-06Clinical Trial Update: Effect of Androgel on Atherogenesis in Type 2 Diabetic Males With Hypogonadotrophic Hypogonadism [NA]
Clinical trial evaluating the effect of Androgel on atherogenesis in men with type 2 diabetes and hypogonadotrophic hypogonadism; study term…
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Reprometabolic Syndrome Mediates Subfertility in Obesity [NA]
This clinical trial update discusses reprometabolic syndrome as a mediator of subfertility in obesity. The trial's results were posted in 20…
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CLINICAL_TRIALS trial_result · 2023-05-18Clinical Trial Update: A 6 Month Safety Extension Study of MBGS205 [Phase 2]
Phase 2 safety extension study completed for MBGS205 in hypogonadotropic hypogonadism; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2022-06-29Clinical Trial Update: Hypogonadotropic Hypogonadism in Obese Young Males [Phase 2]
Phase 2 clinical trial update on hypogonadotropic hypogonadism in obese young males; study terminated with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Efficacy and Safety of Corifollitropin Alfa (MK-8962) in Combination With Human Chorionic Gonadotropin (hCG) in Adolescent Males With Hypogonadotropic Hypogonadism (HH) (MK-8962-043) [Phase 3]
Phase 3 trial MK-8962-043 evaluated the efficacy and safety of corifollitropin alfa (MK-8962) in combination with hCG in adolescent males wi…
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CLINICAL_TRIALS trial_result · 2021-03-03Clinical Trial Update: LutrePulse Hypogonadotropic Hypogonadism [Phase 3]
Phase 3 clinical trial update for LutrePulse addressing hypogonadotropic hypogonadism presenting as primary amenorrhea; study completed with…
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CLINICAL_TRIALS trial_result · 2020-11-25Clinical Trial Update: Safety and Efficacy of BGS649 in Male Obese Subjects With Hypogonadotropic Hypogonadism [Phase 2]
Phase 2 clinical trial assessing safety and efficacy of BGS649 in male obese subjects with hypogonadotropic hypogonadism has completed with …
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CLINICAL_TRIALS trial_result · 2019-10-04Clinical Trial Update: Hypogonadism in Young Men With Type 2 Diabetes [Phase 2]
Phase 2 trial investigating hypogonadism in men with type 2 diabetes; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-08-13Clinical Trial Update: Effect of Intranasal Insulin on LH Concentrations in Man [Phase 1, Phase 2]
A clinical trial assessing the effect of intranasal insulin on luteinizing hormone concentrations in humans with hypogonadotropic hypogonadi…
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Effect of Varying Testosterone Levels on Insulin Sensitivity in Men With Idiopathic Hypogonadotropic Hypogonadism (IHH) [Phase 1]
Phase 1 study assessing how different testosterone levels influence insulin sensitivity in men with idiopathic hypogonadotropic hypogonadism…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: A Phase 2a Pharmacodynamic Study of TAK-448 in Participants With Hypogonadotropic Hypogonadism [Phase 2]
TAK-448 was evaluated in a Phase 2a pharmacodynamic study for Hypogonadotropic Hypogonadism, but the trial was terminated and results were p…
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: A Study of the Efficacy and Safety of Corifollitropin Alfa (MK-8962) in Combination With Human Chorionic Gonadotropin (hCG) in Adult Men With Hypogonadotropic Hypogonadism (HH) (P07937) [Phase 3]
Phase 3 trial evaluating corifollitropin alfa in combination with hCG for adult men with hypogonadotropic hypogonadism; the study is complet…
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CLINICAL_TRIALS trial_result · 2016-03-10Clinical Trial Update: Efficacy of Pulsatile GnRH Therapy on Male Patients With Pituitary Stalk Interruption Syndrome [NA]
This clinical trial update assesses the efficacy of pulsatile GnRH therapy in male patients with Pituitary stalk interruption syndrome; the …
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CLINICAL_TRIALS trial_result · 2015-05-06Clinical Trial Update: Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation in Patients With Hypogonadotropic Hypogonadism [Phase 4]
Phase 4 clinical trial update comparing two induction-of-ovulation protocols to assess ART outcomes in patients with hypogonadotropic hypogo…
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CLINICAL_TRIALS trial_result · 2014-11-06Clinical Trial Update: Follow-up of Serum Androgen Profile After Bariatric Surgery in Men With Obesity Related Hypogonadotropic Hypogonadism
This entry notes a completed clinical trial investigating the effect of bariatric surgery on serum androgen levels in men with obesity-relat…