Hypogonadotropic Hypogonadism
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CLINICAL_TRIALS trial_result · 2026-08-26Clinical Trial Results: Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism [Phase 2]
Phase 2 trial results evaluating prolonged pulsatile kisspeptin administration for hypogonadotropic hypogonadism.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: The Molecular Basis of Inherited Reproductive Disorders
Clinical trial update describing research into the molecular basis of inherited reproductive disorders, including hypogonadotropic hypogonad…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH and FSH Deficiency Undergoing ART (HINATA) [Phase 3]
A Phase 3 clinical trial (HINATA) comparing follitropin alfa/lutropin alfa versus hMG in Japanese participants with LH and FSH deficiency un…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Prolonged Pulsatile Kisspeptin Administration in Hypogonadotropic Hypogonadism [Phase 2]
Phase 2 trial evaluating prolonged pulsatile kisspeptin administration for hypogonadotropic hypogonadism has completed, with an update on st…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Opioid Antagonism in Hypogonadotropic Hypogonadism [Phase 1]
Phase 1 clinical trial evaluating opioid antagonism in hypogonadotropic hypogonadism has completed. The trial addresses low testosterone in …
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Kisspeptin Administration Subcutaneously to Patients With Hypothalamic Amenorrhea [Phase 2]
A Phase 2 trial is evaluating subcutaneous Kisspeptin in patients with hypothalamic amenorrhea, including those with hypogonadotropic hypogo…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: The REgistry of Very Early Estrogen and AnovuLation
A Mayo Clinic-sponsored registry study called The Registry of Very Early Estrogen and Anovulation is currently recruiting participants for c…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Kisspeptin Administration Subcutaneously to Patients With Reproductive Disorders [Phase 1]
Phase 1 trial evaluating subcutaneous kisspeptin in people with reproductive disorders; the study focusing on hypothalamic amenorrhea and hy…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Kisspeptin Administration Subcutaneously to Patients With IHH [Phase 2]
A Phase 2 clinical trial is evaluating subcutaneous kisspeptin administration in patients with hypogonadotropic hypogonadism and is currentl…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism [Phase 4]
Phase 4 clinical trial update evaluating whether aromatase inhibitors promote weight loss in severely obese men with hypogonadotropic hypogo…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Hypogonadotrophic Hypogonadism in Genetic Neurodevelopmental Conditions
A University of Sheffield-sponsored study on hypogonadotropic hypogonadism in genetic neurodevelopmental disorders is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism [Phase 4]
Phase 4 trial assessing the effect of testosterone replacement therapy on blood pressure in adult male participants with hypogonadism; resul…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Assessment of Endometrial Thickness Among Adolescent and Young Adult Patients on Estrogen Replacement Therapy Using Daily Oral Micronized Progesterone Versus the Etonogestrel Implant.
This clinical trial assesses endometrial thickness in adolescent and young adult patients on estrogen replacement therapy, comparing daily o…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Product Transference Study of Testagen™ TDS®-Testosterone [Phase 2]
Phase 2 clinical trial update for Testagen TDS transdermal testosterone evaluating product transference. The study targets hypogonadotropic …
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Triptorelin for Early Diagnosis of Hypogonadotrophic Hypogonadism [NA]
A clinical trial update indicates that Triptorelin is being studied for early diagnosis of hypogonadotropic hypogonadism. The trial is curre…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Neuropeptides in Human Reproduction [Phase 1]
A Phase 1 trial conducted by Massachusetts General Hospital investigating neuropeptides in human reproduction for hypogonadotropic hypogonad…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Kisspeptin Administration in the Adult [Phase 1]
Phase 1 clinical trial evaluating Kisspeptin administration in adults with hypogonadotropic hypogonadism and related GnRH deficiencies, incl…
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CLINICAL_TRIALS trial_result · 2024-02-15Clinical Trial Update: A Randomized, Double-blinded, Clinical, Placebo-controlled Trial on the Effects of Therapy With Letrozole and hUman Choriongonadotropin in Male Hypogonadism Induced by Illicit Use of Anabolic Androgenic Steroids- The LUCAS Trial [Phase 4]
Phase 4 randomized trial assessing letrozole and hCG therapy for male hypogonadism induced by anabolic steroid use; the study status is term…
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FDA approval · 2024-02-07FDA Approved: FOLLISTIM AQ — Supplemental Application (Organon LLC)
FDA approved a supplemental application for FOLLISTIM AQ (FOLLITROPIN) from Organon LLC. The action updates the regulatory status for the pr…
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CLINICAL_TRIALS trial_result · 2024-02-06Clinical Trial Update: Effect of Androgel on Atherogenesis in Type 2 Diabetic Males With Hypogonadotrophic Hypogonadism [NA]
Clinical trial evaluating the effect of Androgel on atherogenesis in men with type 2 diabetes and hypogonadotrophic hypogonadism; study term…
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FDA approval · 2023-11-21FDA Approved: GONAL-F — Supplemental Application (EMD Serono, Inc.)
The FDA approved a supplemental application for GONAL-F (follitropin alfa) submitted by EMD Serono, Inc.
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Reprometabolic Syndrome Mediates Subfertility in Obesity [NA]
This clinical trial update discusses reprometabolic syndrome as a mediator of subfertility in obesity. The trial's results were posted in 20…
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CLINICAL_TRIALS trial_result · 2023-05-18Clinical Trial Update: A 6 Month Safety Extension Study of MBGS205 [Phase 2]
Phase 2 safety extension study completed for MBGS205 in hypogonadotropic hypogonadism; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2022-06-29Clinical Trial Update: Hypogonadotropic Hypogonadism in Obese Young Males [Phase 2]
Phase 2 clinical trial update on hypogonadotropic hypogonadism in obese young males; study terminated with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Efficacy and Safety of Corifollitropin Alfa (MK-8962) in Combination With Human Chorionic Gonadotropin (hCG) in Adolescent Males With Hypogonadotropic Hypogonadism (HH) (MK-8962-043) [Phase 3]
Phase 3 trial MK-8962-043 evaluated the efficacy and safety of corifollitropin alfa (MK-8962) in combination with hCG in adolescent males wi…