Hyperuricemia
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CLINICAL_TRIALS trial_result · 2026-07-28Clinical Trial Results: Uric Acid Lowering Trial in Youth Onset T2D [Phase 2]
Phase 2 trial results for an uric acid-lowering therapy in youth-onset type 2 diabetes; study is completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-06-10Clinical Trial Results: Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients With Hyperuricemia [Phase 1, Phase 2]
Open-label pharmacokinetic, pharmacodynamic, and drug-drug interaction study of dotinurad with allopurinol in gout patients with hyperuricem…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Long-Term Risk of Gout in Living Kidney Donors
A completed clinical trial update assessing the long-term risk of gout among living kidney donors.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Identification and Characterization of At-risk MASLD in Turkish Adults
This completed clinical trial identifies and characterizes individuals at risk for Metabolic dysfunction-associated steatotic liver disease …
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: The Efficacy and Safety of SHR4640 Tablet Combined With 40 mg Febuxostat Tablets in the Treatment of Primary Gout and Hyperuricemia [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of SHR4640 tablets in combination with febuxostat 40 mg for primary gout and hyper…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Clinical Trial of BR2251 Tablets for Patients With Primary Gout and Hyperuricemia [Phase 2]
Phase 2 clinical trial update for BR2251 tablets in primary gout with hyperuricemia; the study is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Evaluation of Efficacy and Safety of AR882 and XOI Co-administration in Uricase Treatment Failed Patients [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of AR882 with a xanthine oxidase inhibitor co-administration in gout patients who …
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-Effectiveness [Phase 4]
Phase 4 clinical trial evaluating HLA-B*58:01-guided therapy for gout to assess effectiveness, safety, and cost-effectiveness; recruitment n…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Study to Assess Efficay and Safety of LC350189 Different Doses in Gout Patients With Hyperuricemia [Phase 2]
A Phase 2 trial evaluated different doses of LC350189 for efficacy and safety in patients with gout and hyperuricemia; trial results have be…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Effectiveness of Digital Health Intervention on Community Health Care in Middle-aged and Older Population in Taiwan [NA]
A completed clinical trial from Chang Gung Memorial Hospital evaluating the effectiveness of a digital health intervention on community heal…
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Tigulixostat, Phase 3 Study, Placebo Controlled in Gout Patients [Phase 3]
LG Chem reports completion of a Phase 3, placebo-controlled trial of tigulixostat in patients with gout and hyperuricemia; the study status …
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Clinical Study of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults [Phase 3]
A Phase 3 clinical trial evaluating HR091506 tablets for gout with hyperuricemia in adults has completed.
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-301) [Phase 3]
This entry notes a Phase 3 clinical trial (AR882-301) evaluating the efficacy and safety of AR882 in gout patients. The trial is currently a…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Clinical Effect Observation of Barley Green Intervention in Hyperuricemia Population and Related Mechanism Study of Xanthine Oxidase [NA]
This clinical trial update reports a completed study evaluating a barley green intervention in hyperuricemia and investigates the mechanism …
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients [Phase 3]
LG Chem's Phase 3 trial evaluating tigulixostat in gout patients with allopurinol as control has completed.
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Relationship Between Intestinal Flora Changes and Hyperuricemia Under Chronic Psychological Stress
This completed clinical trial examined whether chronic psychological stress-induced changes in gut microbiota are associated with hyperurice…
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: The Effect of Exercise at Different Time Intervals on Hyperuricemia [NA]
This completed clinical trial examined whether exercising at different time intervals influences hyperuricemia in participants.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: A Dose Finding Study to Assess Efficacy and Safety of IBI128 in Chinese Gout Subjects [Phase 2]
A Phase 2 dose-finding trial evaluating the efficacy and safety of IBI128 in Chinese patients with gout and hyperuricemia has completed.
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid Levels [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of PRX-115 in adults with elevated uric acid levels (g…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Phase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination With Allopurinol in Patients With Tophaceous Gout [Phase 2]
A Phase 2 clinical trial update evaluating AR882 alone or in combination with allopurinol for tophaceous gout has completed, focusing on eff…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients with Hyperuricemia [Phase 1, Phase 2]
This open-label PK, PD, and DDI study evaluated dotinurad in combination with allopurinol in gout patients with hyperuricemia and has comple…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Effect of Increased Daily Water Intake in Patients With Hyperuricemia [NA]
A completed clinical trial evaluating whether increasing daily water intake affects hyperuricemia.
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: PK and Safety Evaluation Study of SAP-001 in Adult Subjects With Normal and Impaired Renal Function [Phase 1, Phase 2]
This clinical trial update describes pharmacokinetic and safety evaluation of SAP-001 in adult subjects with normal and impaired renal funct…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Non-Inferiority Study of Aliskiren vs Losartan in the Treatment of Hypertension With Hyperuricemia [Phase 4]
Phase 4 trial updates completion of a non-inferiority study comparing aliskiren to losartan for hypertension with hyperuricemia.
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: SAD,MAD and Food Effect Study of SAP-001 Tablets in Chinese Subjects [Phase 1]
Phase 1 SAD/MAD and food-effect study of SAP-001 tablets in Chinese subjects has completed. Sponsor: Shanton Pharma Co., Ltd.