Hypertrophic Obstructive Cardiomyopathy
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Myocardial Perfusion Changes Following Optimal Medical Treatment in Symptomatic Hypertrophic Cardiomyopathy
This ClinicalTrials.gov update describes a study assessing changes in myocardial perfusion after optimal medical therapy in symptomatic hype…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: A Cardiac Disease Quality of Life Study
The Cleveland Clinic-sponsored trial is recruiting to evaluate quality of life in patients with hypertrophic obstructive cardiomyopathy and …
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Positron Emission Tomography to Assess the Effect of Camzyos on Ischaemia in HOCM: PEACH Trial [NA]
A clinical trial update describing the PEACH study, which will use PET imaging to evaluate whether mavacamten (Camzyos) reduces myocardial i…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Clinical Outcomes of PIMSRA Treating for Hypertrophic Obstructive Cardiomyopathy: A Large-Sample Study
This clinical trial update reports the clinical outcomes of using PIMSRA to treat hypertrophic obstructive cardiomyopathy in a large-sample …
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Septal Ablation for Obstructive HCM [NA]
Clinical trial update on septal ablation for hypertrophic obstructive cardiomyopathy; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Electromechanically Optimised Right Ventricular Pacing In Hypertrophic Cardiomyopathy (EMORI-HCM) [NA]
This clinical trial update reports on the EMORI-HCM study evaluating electromechanically optimised right ventricular pacing in hypertrophic …
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: First-in-Man Early Feasibility Study for Transcatheter HOCM Septal Ablation [NA]
First-in-man early feasibility study of transcatheter septal ablation for hypertrophic obstructive cardiomyopathy was terminated.
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: A Study of Mavacamten in Obstructive Hypertrophic Cardiomyopathy [Phase 3]
A Phase 3 trial evaluating mavacamten for obstructive hypertrophic cardiomyopathy has completed, and results have been posted.
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: Transapical Beating-heart Septal Myectomy in Patient With Hypertrophic Obstructive Cardiomyopathy [NA]
This is a clinical trial update indicating recruitment is ongoing for a study on transapical beating-heart septal myectomy in patients with …
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Postoperative Pain for Patients After TA-BSM
Clinical trial update indicating the study on postoperative pain management after Transapical Beating-heart Septal Myectomy has completed.
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Efficacy and Safety of Thoracoscopic Morrow Surgery in the Treatment of Hypertrophic Obstructive Cardiomyopathy [NA]
A clinical trial evaluating the efficacy and safety of thoracoscopic Morrow surgery for hypertrophic obstructive cardiomyopathy, currently r…
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CLINICAL_TRIALS trial_result · 2023-03-07Clinical Trial Update: A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy [Phase 3]
Phase 3 trial evaluating mavacamten in adults with symptomatic obstructive hypertrophic cardiomyopathy completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2023-01-17Clinical Trial Update: Mobilization of Endothelial Progenitor Cells and Aspirin [Phase 3]
A Phase 3 trial investigating mobilization of endothelial progenitor cells and aspirin in hypertrophic obstructive cardiomyopathy was termin…
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CLINICAL_TRIALS trial_result · 2022-11-08Clinical Trial Update: Quantitative Assessment of Hypertrophic Obstructive Cardiomyopathy With Intraoperative Three-dimensional Transesophageal Echocardiography Under Provocative Dobutamine Stress Test [Phase 4]
Phase 4 clinical trial evaluating intraoperative 3D transesophageal echocardiography under provocative dobutamine stress in hypertrophic obs…
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CLINICAL_TRIALS trial_result · 2021-10-11Clinical Trial Update: Esmolol for Myocardial Protection in Hypertrophic Obstructive Cardiomyopathy [Phase 4]
Phase 4 trial update evaluating esmolol for myocardial protection in hypertrophic obstructive cardiomyopathy (HOCM).
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CLINICAL_TRIALS research · 2016-10-20Clinical Trial Update: CArdiac Desynchronization In Obstructive HCM, CARDIO-HCM [Phase 2]
Phase 2 clinical trial update from Hospital Clinic of Barcelona evaluating cardiac desynchronization in Hypertrophic Obstructive Cardiomyopa…
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CLINICAL_TRIALS research · 2016-10-04Clinical Trial Update: Evaluate the Efficacy of Disopyramide Therapy in Hypertrophic Obstructive Cardiomyopathy Patients [NA]
Clinical trial update evaluating the efficacy of disopyramide therapy in hypertrophic obstructive cardiomyopathy; the current status of the …
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CLINICAL_TRIALS trial_result · 2016-09-02Clinical Trial Update: Echocardiography-guided Transthoracic Radio Frequency/Laser Ablation for Ventricular Septum of Hypertrophic Obstructive Cardiomyopathy [NA]
This document provides a clinical trial update on using echocardiography-guided transthoracic radiofrequency/laser ablation of the ventricul…
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CLINICAL_TRIALS research · 2016-03-22Clinical Trial Update: Comparisonof Extended Myoectomy and Myoectomy by Morrow in Patients With Hypertrophic Obstructive Cardiomyopathy (HOCM) [NA]
This clinical trial update discusses a comparison between extended myectomy and the Morrow technique for hypertrophic obstructive cardiomyop…
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Surgical Treatment of Hypertrophic Obstructive Cardiomyopathy With Severe Mitral Insufficiency. [NA]
Clinical trial update on the completed study evaluating surgical treatment for hypertrophic obstructive cardiomyopathy with severe mitral in…
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CLINICAL_TRIALS research · 2013-06-11Clinical Trial Update: CRyo-Ablation to Treat Patients With HOCM. [NA]
This clinical trial update discusses a study evaluating cryo-ablation to treat hypertrophic obstructive cardiomyopathy (HOCM), sponsored by …
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FDA approval · 2008-03-20FDA Approved: PROPRANOLOL HYDROCHLORIDE — Supplemental Application (Amneal Pharmaceuticals NY LLC)
FDA approves a supplemental application for propranolol hydrochloride from Amneal Pharmaceuticals NY LLC.