Hypertrophic Cardiomyopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-05-01Clinical Trial Update: Genotype-Phenotype Associations in Pediatric Cardiomyopathy (PCM GENES)
A completed pediatric cardiomyopathy genotype-phenotype study (NCT01873963) sponsored by Wayne State University, examining genotype-phenotyp…
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China
A clinical trial in China is exploring an integrative 'omics' approach to diagnose and prognosticate various forms of cardiomyopathy, includ…
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy [Phase 2, Phase 3]
Phase 2/3 trial evaluating Eleclazine (GS-6615) for improving exercise capacity in symptomatic hypertrophic cardiomyopathy was terminated wi…
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: Assessment of Left Ventricular Torsion by Echocardiography Study
A completed clinical trial assessing left ventricular torsion by echocardiography in patients with Hypertrophic Cardiomyopathy; results post…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Non-Invasive Evaluation of Myocardial Stiffness by Elastography in Pediatric Cardiology (Elasto-Pédiatrie) [NA]
The Elasto-Pédiatrie study, which evaluates non-invasive elastography for assessing myocardial stiffness in pediatric patients with dilated …
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: Nitrite in Hypertrophic Cardiomyopathy (HCM) Study [Phase 1]
This document provides an update on a Phase 1 clinical trial evaluating nitrite therapy for hypertrophic cardiomyopathy. The study is sponso…
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure [Phase 2]
An open-label Phase 2 study evaluating Perhexiline in patients with hypertrophic cardiomyopathy and moderate-to-severe heart failure was ter…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Natural History and Results of Dual Chamber (DDD) Pacemaker Therapy of Children With Obstructive Hypertrophic Cardiomyop... [Phase 1]
This Phase 1 trial reports natural history and outcomes of dual-chamber DDD pacemaker therapy in children with obstructive hypertrophic card…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Identification of Risk Factors for Arrhythmia in Children and Adolescents With Hypertrophic Cardiomyopathy
This update reports on a completed clinical trial investigating risk factors for arrhythmia in children and adolescents with hypertrophic ca…
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Deactivation of Implantable Cardioverter Defibrillator During Non-thoracic Surgical Procedures
This clinical trial update discusses strategies for deactivating implantable cardioverter-defibrillators (ICDs) during non-thoracic surgical…
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: Study to Develop a Non-invasive Marker for Monitoring Myocardial Fibrosis [Phase 2]
A Phase 2 study aiming to develop a non-invasive biomarker for monitoring myocardial fibrosis was terminated; the trial involved patients wi…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Prognosis of Subjects With Unexplainable Precordial Deep T-wave Inversion Without Wall Thickness> 15mm
This clinical trial update reports on the prognosis of subjects with unexplainable precordial deep T-wave inversion and wall thickness not e…
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CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: Ranolazine for the Treatment of Chest Pain in HCM Patients [Phase 4]
Phase 4 clinical trial evaluating ranolazine for chest pain in patients with hypertrophic cardiomyopathy, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-461 [Phase 1]
This Phase 1 study update reports safety, tolerability, and preliminary pharmacokinetic and pharmacodynamic data for mavacamten (MYK-461) in…
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CLINICAL_TRIALS trial_result · 2015-09-03Clinical Trial Update: Study of Hypertrophic Cardiomyopathy Under Stress Conditions. Concordance Between Two Complementary Tests: Stress MRI and Exercice Stress Echocardiography [NA]
A clinical trial evaluating concordance between Stress MRI and Exercise Stress Echocardiography in patients with hypertrophic cardiomyopathy…
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CLINICAL_TRIALS trial_result · 2015-04-07Clinical Trial Update: Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem [Phase 2, Phase 3]
Clinical trial update on diltiazem for preclinical hypertrophic cardiomyopathy in Phase 2/3, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2014-08-06Clinical Trial Update: Biventricular Pacing in Hypertrophic Cardiomyopathy After Aortic Valve Replacement [NA]
This clinical trial update indicates that a study evaluating biventricular pacing in hypertrophic cardiomyopathy after aortic valve replacem…
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CLINICAL_TRIALS trial_result · 2014-07-09Clinical Trial Update: Inhibition of the Renin Angiotensin System With Losartan in Patients With Hypertrophic Cardiomyopathy [Phase 2]
A Phase 2 trial evaluating losartan, a renin-angiotensin system inhibitor, for hypertrophic cardiomyopathy has completed.
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CLINICAL_TRIALS trial_result · 2014-03-26Clinical Trial Update: Neurohormonal Parameters in Hypertrophic Cardiomyopathies [NA]
This completed clinical trial assessed neurohormonal parameters across primary sarcomeric, obstructive, and non-obstructive hypertrophic car…
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CLINICAL_TRIALS trial_result · 2014-03-18Clinical Trial Update: Effects of Highly Active Anti-Retroviral Therapy on Cardiovascular Health in Infants of HIV-Infected Mothers
A completed clinical trial update evaluating the effects of Highly Active Antiretroviral Therapy on cardiovascular health in infants born to…
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CLINICAL_TRIALS trial_result · 2013-12-09Clinical Trial Update: Study to Determine if Atorvastatin Reduces Size and Stiffness of Muscle in the Left Ventricle of the Heart [Phase 3]
A Phase 3 trial sponsored by the University of Calgary tested whether atorvastatin reduces left ventricular muscle size and stiffness in hyp…
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CLINICAL_TRIALS trial_result · 2013-09-05Clinical Trial Update: Effect of Losartan in Patients With Nonobstructive Hypertrophic Cardiomyopathy [Phase 2]
A Phase 2 clinical trial update evaluating losartan in patients with nonobstructive hypertrophic cardiomyopathy, with results posted.
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CLINICAL_TRIALS trial_result · 2013-02-28Clinical Trial Update: Trimetazidine Therapy in Hypertrophic Cardiomyopathy [Phase 2]
A Phase 2 clinical trial evaluating trimetazidine as a therapy for hypertrophic cardiomyopathy; the current status is Unknown.
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CLINICAL_TRIALS trial_result · 2013-02-05Clinical Trial Update: Antiarrhythmic Therapy Versus Catheter Ablation for Atrial Fibrillation in Hypertrophic Cardiomyopathy [Phase 3]
A Phase 3 trial comparing antiarrhythmic therapy versus catheter ablation for atrial fibrillation in hypertrophic cardiomyopathy has complet…
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CLINICAL_TRIALS trial_result · 2010-11-04Clinical Trial Update: Perhexiline Therapy in Patients With Hypertrophic Cardiomyopathy [Phase 2]
This clinical trial update confirms the completion of a Phase 2 study evaluating perhexiline for hypertrophic cardiomyopathy.