Hypertrophic Cardiomyopathy
📧 Sign up to get email alerts when something new happens for Hypertrophic Cardiomyopathy.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2026-08-20Clinical Trial Results: A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy [Phase 3]
Phase 3 trial results for mavacamten in non-obstructive hypertrophic cardiomyopathy have been completed with results posted.
-
CLINICAL_TRIALS trial_result · 2026-08-05Clinical Trial Update: A Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM) [Phase 3]
Phase 3 trial evaluating efficacy and safety of aficamten versus placebo in adults with symptomatic non-obstructive hypertrophic cardiomyopa…
-
CLINICAL_TRIALS trial_result · 2026-07-29Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy [Phase 3]
Phase 3 trial evaluating the efficacy and safety of sotagliflozin in symptomatic obstructive and non-obstructive hypertrophic cardiomyopathy…
-
CLINICAL_TRIALS trial_result · 2026-06-02Clinical Trial Results: A Study to Evaluate the Efficacy, Safety, and Tolerability of MYK-224 in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy [Phase 2]
Phase 2 trial evaluating MYK-224 for symptomatic obstructive hypertrophic cardiomyopathy was terminated; results posted.
-
CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy
The clinical trial update indicates that the mavacamten study in adults with obstructive hypertrophic cardiomyopathy has been completed, wit…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Empagliflozin in Hypertrophic Cardiomyopathy [Phase 3]
Phase 3 trial update shows empagliflozin is being investigated for hypertrophic cardiomyopathy and heart failure, with the study currently a…
-
CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: ENABLE-HCM - AI-ENabled Echocardiography With Ultrasound Beyond the Echo Lab for Better HCM Imaging and Expanded Access
The ENABLE-HCM trial evaluating AI-enabled echocardiography for hypertrophic cardiomyopathy imaging has been terminated.
-
CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM) [Phase 2]
This is a Phase 2 clinical trial update on EDG-7500 for adults with hypertrophic cardiomyopathy (CIRRUS-HCM), noting that the study is curre…
-
CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Hypertrophic Cardiomyopathy [Phase 2]
A Phase 2 dose-finding study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of CK-3773274 in adults with hypertr…
-
CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM [Phase 2, Phase 3]
This clinical trial update notes the completion of a long-term safety extension study of mavacamten in adults who completed MAVERICK-HCM or …
-
CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Pilot Study of Hypertrophic Cardiomyopathy & Implantable Cardioverter Defibrillator Assessment: (Subcutaneous vs Transvenous) [NA]
A pilot trial comparing subcutaneous versus transvenous implantable cardioverter-defibrillators in patients with hypertrophic cardiomyopathy…
-
CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Retrospective Natural History Study of RASopathy-associated Cardiomyopathy (RAS-CM)
A retrospective natural history study of RASopathy-associated cardiomyopathy (RAS-CM) is sponsored by Deutsches Herzzentrum Muenchen and cur…
-
CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Effect of Personalized Accelerated Pacing in Symptomatic Patients With Non-Obstructive Hypertrophic Cardiomyopathy [NA]
A clinical trial evaluating personalized accelerated pacing in symptomatic non-obstructive hypertrophic cardiomyopathy has been terminated.
-
CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Early Feasibility Study [NA]
NHLBI's SESAME early feasibility trial evaluating septal scoring along the midline endocardium in hypertrophic cardiomyopathy and related va…
-
CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: A Trial of HRS-1893 in Healthy Volunteers [EARLY_Phase 1]
An early Phase 1 trial of HRS-1893 in healthy volunteers has completed.
-
CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy [Phase 3]
Phase 3 study of mavacamten for non-obstructive hypertrophic cardiomyopathy has completed.
-
CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: The Efficacy and Mechanism of Trientine in Patients With Hypertrophic Cardiomyopathy [Phase 2]
This Phase 2 trial evaluated the efficacy and potential mechanism of trientine in patients with hypertrophic cardiomyopathy and has complete…
-
CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Intraventricular Stasis In Cardiovascular Disease
A completed clinical trial update on intraventricular stasis in cardiovascular disease. The study involves patients with dilated cardiomyopa…
-
CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Safety and Pharmacokinetics Study of HRS-1893 Tablets in Healthy Subjects and Those With Impaired Kidney Function [Phase 1]
Phase 1 safety and pharmacokinetics study of HRS-1893 tablets in healthy subjects and those with impaired kidney function has completed.
-
CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Tolerability of MYK-224 in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy [Phase 2]
A Phase 2 trial evaluating MYK-224 for symptomatic obstructive hypertrophic cardiomyopathy has been terminated.
-
CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: A Study to Assess Health-Related Quality of Life in Patients With Hypertrophic Cardiomyopathy in Japan
A completed clinical trial conducted in Japan assessed health-related quality of life in patients with hypertrophic cardiomyopathy.
-
CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: The Impact of Exercise-Induced Cardiac Remodeling on Myocardial Efficiency
A completed Massachusetts General Hospital trial examines how exercise-induced cardiac remodeling affects myocardial efficiency in hypertrop…
-
CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations [NA]
Completed clinical trial assessing health-related quality of life and physical activity in children with cardiac malformations, sponsored by…
-
CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: UTSW HP [13-C] Pyruvate Injection in HCM
UT Southwestern completed a clinical trial evaluating a [13-C] pyruvate injection for hypertrophic cardiomyopathy.
-
CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)
This clinical trial update reports completion of a Mayo Clinic–sponsored study investigating the relationship between sleep apnea and hypert…