Hypertriglyceridemia
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: A Study of SHR-1918 In Participants With Hypertriglyceridemia [Phase 3]
A Phase 3 study evaluating SHR-1918 for hypertriglyceridemia is planned. The trial is currently not recruiting.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis [Phase 3]
A Phase 3 clinical trial of Plozasiran in adults with severe hypertriglyceridemia at risk of acute pancreatitis is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia [Phase 2]
A Phase 2 trial evaluating MN-001 in patients with non-alcoholic fatty liver disease and comorbid type 2 diabetes mellitus and hypertriglyce…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Comparison of Cardiometabolic Markers in Individuals With Hypertriglyceridemia With Low and High Weight Loss Responses to an Energy-restricted Diet [NA]
The study compared cardiometabolic markers in individuals with hypertriglyceridemia who had low versus high weight loss responses to an ener…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Different Insulin Resistance Phenotypes [NA]
This clinical trial investigates how hepatic triglyceride biosynthesis varies across insulin resistance phenotypes in people with hypertrigl…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol [Phase 2]
Phase 2 clinical trial evaluating MAR001 in adults with hypertriglyceridemia (including remnant cholesterol); the study is currently active …
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FDA approval · 2026-01-21FDA Approved: FENOFIBRATE — Original Application (Macleods Pharmaceuticals Limited)
FDA approved Macleods Pharmaceuticals Limited's fenofibrate under an Original Application (ANDA 210379). The approval permits the generic fe…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Rosemary Infusion for Hypertension With Hypertriglyceridemia [NA]
A clinical trial evaluating rosemary infusion for hypertension with hypertriglyceridemia has completed.
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: A Phase II Study to Evaluate the Efficacy and Safety of of DR10624 in Subjects With Severe Hypertriglyceridemia [Phase 2]
Phase II clinical trial of DR10624 for severe hypertriglyceridemia has completed; the snippet provides no efficacy or safety results.
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Study of RN0361in Adult Healthy Subjects and Adult Hypertriglyceridemic Subjects [Phase 1, Phase 2]
RN0361 is being studied in healthy adults and adults with hypertriglyceridemia (including familial chylomicronemia syndrome) in Phase 1 and …
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: a Phase 1b/2a Study of JMT202 Injection in Participants With Hypertriglyceridemia [Phase 1, Phase 2]
A Phase 1b/2a study of JMT202 injection for hypertriglyceridemia is currently recruiting, sponsored by Shanghai JMT-Bio Inc.
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS) [Phase 1]
Phase 1 study evaluating ARO-APOC3 in healthy volunteers and patients with hypertriglyceridemia or familial chylomicronemia syndrome has com…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients [Phase 1]
Phase 1 study of ARO-ANG3 in healthy volunteers and dyslipidemic patients has completed; the update provides status of the trial.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists [Phase 2]
Phase 2 trial evaluating RDX-002's effect on postprandial triglycerides in patients discontinuing GLP-1 agonists; study completed.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Efficacy and Safety of Cipros 10 Association on the Isolated Hypertriglyceridemia and Dyslipidemia Treatment [Phase 3]
Phase 3 trial evaluating the efficacy and safety of Cipros 10 Association for isolated hypertriglyceridemia and dyslipidemia has completed.
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: CORE-OLE: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG) [Phase 3]
Phase 3 trial update for Olezarsen (ISIS 678354) in severe hypertriglyceridemia; the CORE-OLE study is currently active but not recruiting p…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia [Phase 1]
A Phase 1b clinical trial evaluating VERVE-201 for patients with refractory hyperlipidemia is currently recruiting to assess safety and phar…
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CLINICAL_TRIALS trial_result · 2025-11-13Clinical Trial Update: Study of MAR001 in Adults With Metabolic Dysfunction [Phase 1, Phase 2]
A clinical trial of MAR001 in adults with metabolic dysfunction focusing on hypertriglyceridemia has completed Phase 1 and Phase 2.
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol [Phase 2]
A Phase 2 mechanistic study investigating MAR001 in adults with elevated triglycerides and remnant cholesterol is currently recruiting.
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CLINICAL_TRIALS approval · 2025-10-28Clinical Trial Update: Compassionate Use of Evinacumab
Evinacumab (brand Evkeeza) has gained marketing approval for use in pediatric homozygous familial hypercholesterolemia, as well as indicatio…
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Study of Plozasiran (ARO-APOC3) in Adults With Severe Hypertriglyceridemia [Phase 3]
This entry updates the status of a Phase 3 trial evaluating Plozasiran (ARO-APOC3) in adults with severe hypertriglyceridemia, noting the st…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Study of Plozasiran in Adults With Severe Hypertriglyceridemia [Phase 3]
Phase 3 trial status update for Plozasiran in adults with severe hypertriglyceridemia, currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia [Phase 3]
Phase 3 trial of olezarsen administered subcutaneously in adults with severe hypertriglyceridemia has completed.
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia [Phase 3]
Phase 3 trial update indicating the study of Plozasiran in adults with hypertriglyceridemia is currently not recruiting.
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Differential Thrombogenesis by EPA and DHA Mediated by HDL [EARLY_Phase 1]
Early-phase trial evaluating differential thrombogenesis by EPA versus DHA mediated by HDL in lipid metabolism disorders, currently recruiti…