Hypertriglyceridemia
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CLINICAL_TRIALS trial_result · 2016-08-17Clinical Trial Update: Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®) [Phase 1]
Phase 1 study evaluating potential drug-drug interaction between multiple doses of Epanova and a single dose of rosuvastatin (Crestor) in hy…
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CLINICAL_TRIALS trial_result · 2016-08-08Clinical Trial Update: Trial of ARI-3037MO to Reduce Triglyceride Levels in Adults With Severe (≥500 mg/dl) Hypertriglyceridemia [Phase 2]
This clinical trial update reports completion of a Phase 2 trial evaluating ARI-3037MO to reduce triglyceride levels in adults with severe h…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia [Phase 2]
Phase 2 pilot study evaluating CAT-2003 in patients with dyslipidemia was completed.
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CLINICAL_TRIALS trial_result · 2016-07-21Clinical Trial Update: Pilot Study To Assess CAT-2003 in Patients With Chylomicronemia [Phase 2]
A Phase 2 pilot study evaluating CAT-2003 for familial chylomicronemia syndrome and related lipid disorders has completed.
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CLINICAL_TRIALS trial_result · 2016-06-20Clinical Trial Update: An Open-Label Crossover Study to Compare the Relative Bioavailability, Efficacy and Safety of Epanova® and Lovaza® in Men and Women With a History of Pancreatitis [Phase 1]
Completed Phase 1 open-label crossover trial comparing the relative bioavailability, efficacy and safety of Epanova and Lovaza in men and wo…
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CLINICAL_TRIALS trial_result · 2016-06-09Clinical Trial Update: Investigating the Effects of Glucodia™ on Glucose Parameters, Triglycerides and Body Weight [Phase 2]
A Phase 2 clinical trial evaluating the effects of Glucodia on glucose parameters, triglycerides, and body weight has completed.
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Study to Assess the Safety and Tolerability of Single Doses of REGN1500 [Phase 1]
Phase 1 study evaluating the safety and tolerability of single doses of REGN1500 in hypertriglyceridemia has completed.
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CLINICAL_TRIALS trial_result · 2016-05-05Clinical Trial Update: Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides. [NA]
This completed clinical trial compared fenofibrate (Tricor), rosiglitazone (Avandia), and a weight-loss intervention to reduce cardiovascula…
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: Efficacy of LCQ908 on Cardiovascular Risk [Phase 2]
Phase 2 trial evaluating LCQ908 for cardiovascular risk in coronary artery disease and hypertriglyceridemia was terminated, with results pos…
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated Hypertriglyceridemia [Phase 4]
Phase 4 clinical trial evaluating omega-3 fatty acids (Lovaza) for hypertriglyceridemia associated with second-generation antipsychotics. Re…
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CLINICAL_TRIALS trial_result · 2016-03-21Clinical Trial Update: Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or Dyslipidemia [NA]
A completed clinical trial evaluated whether diet, exercise, niacin, and fenofibrate could reduce cardiovascular risk factors in people with…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Re-evaluating Triglycerides in Coronary Heart Disease
This NHLBI-sponsored clinical trial on triglycerides in coronary heart disease has completed. It re-evaluated whether triglyceride levels in…
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Genetic Determinants:Low HDL, High Triglycerides, Obesity
NHLBI-sponsored clinical trial update examining genetic factors linked to low HDL, high triglycerides, and obesity and their relation to car…
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CLINICAL_TRIALS trial_result · 2016-02-03Clinical Trial Update: Effects of Acipimox on Mitochondrial Function in Obesity [Phase 2]
Phase 2 trial evaluating acipimox effects on mitochondrial function in obesity; results have been posted after study completion.
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CLINICAL_TRIALS trial_result · 2016-01-27Clinical Trial Update: A Pilot Study to Evaluate the Lipid Effects of TRIA-662 [Phase 2]
A Phase 2 pilot trial evaluating the lipid effects of TRIA-662 in hypertriglyceridemia and mixed hyperlipidemia has completed.
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CLINICAL_TRIALS trial_result · 2016-01-15Clinical Trial Update: Epanova® for Lowering Very High Triglycerides II (EVOLVE II) [Phase 3]
Phase 3 trial EVOLVE II evaluating Epanova for lowering very high triglycerides has completed and results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: Safety and Efficacy of a Natural Health Product in Reducing Cholesterol and Triglyceride Levels. [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating a natural health product for safety and efficacy in lowering LDL cholesterol and triglycerides has complete…
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CLINICAL_TRIALS trial_result · 2015-12-09Clinical Trial Update: Omega-3-Acid Ethyl Esters 90 Soft Capsules for Lowering Very High Triglycerides [Phase 3]
Phase 3 clinical trial evaluating Omega-3-Acid Ethyl Esters 90 Soft Capsules to lower very high triglycerides is in progress. The current st…
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CLINICAL_TRIALS trial_result · 2015-10-30Clinical Trial Update: The Efficacy and Safety of PRC-4016 in Hypertriglyceridemic Subjects [Phase 2]
Phase 2 trial update reporting efficacy and safety results for PRC-4016 in hypertriglyceridemic subjects. The study has completed.
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CLINICAL_TRIALS trial_result · 2015-10-14Clinical Trial Update: Predictors of Response to Fenofibrate
This clinical trial update identifies predictors of response to fenofibrate in patients with hypertriglyceridemia and insulin resistance.
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CLINICAL_TRIALS trial_result · 2015-08-14Clinical Trial Update: Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia [Phase 2]
The document reports the completion status of a Phase 2 pilot study evaluating CAT-2003 in patients with severe hypertriglyceridemia.
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CLINICAL_TRIALS trial_result · 2015-04-30Clinical Trial Update: The Effect of Multiple Doses of Epanova® on the Multiple-Dose Pharmacokinetics of Simvastatin in Healthy Normal Subjects [Phase 1]
Phase 1 study evaluating the effect of multiple doses of Epanova on the pharmacokinetics of simvastatin in healthy subjects; study status is…
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CLINICAL_TRIALS trial_result · 2015-04-30Clinical Trial Update: An Open-Label Treatment Protocol to Provide Metreleptin for the Treatment of Diabetes Mellitus and/or Hypertriglyceridemia Associated With Lipodystrophy [NA]
An open-label clinical trial protocol uses metreleptin to treat diabetes mellitus and/or hypertriglyceridemia associated with lipodystrophy,…
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CLINICAL_TRIALS trial_result · 2015-04-24Clinical Trial Update: Interaction of Epanova on Warfarin Pharmacokinetic and Anticoagulant Activity and Comparison of the Effects of Epanova and Lovaza on Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) After Low-fat Meals [Phase 1]
Phase 1 study evaluating warfarin pharmacokinetics and anticoagulant activity with Epanova, and comparing EPA/DHA effects of Epanova versus …
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: A Study to Evaluate Fenofibrate Combination With Statin in Chinese Patients With Dyslipidemic [Phase 4]
A Phase 4 study evaluating the combination of fenofibrate with a statin in Chinese patients with dyslipidemia, with results posted.