Hypersensitivity
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia
This entry describes a National Institute of Allergy and Infectious Diseases clinical trial investigating how eosinophils activate and funct…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing, Immunotherapy or Oral Challenges [Phase 1]
Phase 1 trial studying whether inhaled epinephrine can lessen systemic allergic reactions during allergy testing, immunotherapy, or oral cha…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing Immunotherapy or Oral Challenges [Phase 1]
Phase 1 trial evaluating inhaled epinephrine to attenuate systemic allergic reactions during allergy testing and oral challenges has complet…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Measures for Bioaerosol Reduction in the Salmon Industry [NA]
Clinical trial evaluating methods to reduce bioaerosols in the salmon industry, currently enrolling by invitation and focused on occupationa…
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CLINICAL_TRIALS trial_result · 2024-08-05Clinical Trial Update: Assessment of Er:YAG Laser for the Control of Hypersensitivity During Tooth Whitening With Hydrogen Peroxide [NA]
A clinical trial evaluating the use of an Er:YAG laser to control hypersensitivity during hydrogen peroxide tooth whitening is currently not…
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CLINICAL_TRIALS trial_result · 2022-09-15Clinical Trial Update: Skin Prick Test of KeraStat® Cream [NA]
A completed clinical trial evaluating a skin prick test for KeraStat cream, results posted in 2022, under hypersensitivity conditions.
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CLINICAL_TRIALS trial_result · 2022-06-02Clinical Trial Update: Vestibular Versus Sublingual Route of AIT Tablets [Phase 4]
Phase 4 clinical trial comparing vestibular versus sublingual routes of allergen immunotherapy tablets for hypersensitivity conditions has c…
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EMA withdrawal · 2022-05-20EMA Application withdrawn: Neffy (epinephrine) — Ars Pharmaceuticals Irl Limited
The EMA withdrew the application for Neffy (epinephrine) by Ars Pharmaceuticals Irl Limited.
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Caries Prevention Products & Dentinal Hypersensitivity [NA]
Clinical trial update on caries prevention products and dentinal hypersensitivity; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-09-25Clinical Trial Update: Study to Determine Skin Irritation and/or Sensitization Potential of an Antifungal Cream Containing Trolamine (Repeated Insult Patch Test) [Phase 3]
A Phase 3 trial evaluating skin irritation and/or sensitization potential of an antifungal cream containing trolamine; study completed with …
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CLINICAL_TRIALS trial_result · 2020-09-25Clinical Trial Update: Study to Determine Skin Irritation Potential of an Antifungal Cream Containing Trolamine After Repeated Skin Application (Cumulative Irritation Patch Test) [Phase 3]
Phase 3 trial assessing skin irritation potential of an antifungal cream containing trolamine after repeated skin application; study complet…
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Clinical Assessment of Bifluorid 10 vs Varnish Fluoride on The Exposed Hypersensitive Cervical Dentin in Adult Patient [Phase 2, Phase 3]
Clinical trial update comparing Bifluorid 10 versus varnish fluoride for exposed hypersensitive cervical dentin in adults, spanning Phase 2 …
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CLINICAL_TRIALS trial_result · 2018-09-04Clinical Trial Update: DBPC-Dose-finding-trial of Vitamin D3 for SCIT in Birch Pollen Allergic Patients. [Phase 2]
Phase 2 dose-finding trial of Vitamin D3 as an adjuvant for subcutaneous immunotherapy in birch pollen hypersensitivity has completed.
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: Non-Pharmaceutical Treatment of Seasonal Allergic Conjunctivitis [Phase 4]
Phase 4 clinical trial update on non-pharmaceutical treatment for seasonal allergic conjunctivitis focusing on hypersensitivity conditions; …
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CLINICAL_TRIALS trial_result · 2017-12-26Clinical Trial Update: Asthma Data Innovation Demonstration Project [NA]
Clinical trial update for an asthma-focused data innovation demonstration project; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: A Pilot Study to Evaluate the Efficacy of Refined Methods to Mitigate Indoor Allergens in North Carolina and Boston, Massachusetts Homes
A completed pilot trial evaluated refined methods to mitigate indoor allergens in homes in North Carolina and Boston, aiming to reduce hyper…
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CLINICAL_TRIALS trial_result · 2017-05-01Clinical Trial Update: Determination of Biological Activity of Three Allergen Extracts [Phase 2]
Phase 2 trial assessing the biological activity of three allergen extracts for hypersensitivity; the study status is completed.
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: Skin Tests in Cat Allergic Patients With Cat Dander Samples Obtained Before and After Vaccinating the Cat [NA]
A completed University of Zurich clinical trial evaluated skin test responses in cat-allergic patients using cat dander samples collected be…
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CLINICAL_TRIALS trial_result · 2015-10-02Clinical Trial Update: A Study to Evaluate the Incidence of Hypersensitivity After Administration of Sugammadex in Healthy Participants (MK-8616-101) [Phase 1]
Phase 1 trial assessing hypersensitivity incidence after sugammadex administration in healthy participants; results completed with posted re…
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CLINICAL_TRIALS research · 2012-10-03Clinical Trial Update: Health2006 - an Observational Study of Cardiovascular Disease, Diabetes, Asthma and Allergy
Health2006 is an observational study on cardiovascular disease, type 2 diabetes, asthma, hypersensitivity, and osteoporosis that has complet…
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CLINICAL_TRIALS trial_result · 2010-11-01Clinical Trial Update: The Duration of the Suppressive Effects of Desloratadine on Allergen Prick Tests After Discontinuation (P04441) [Phase 4]
Phase 4 clinical trial updating the duration of suppressive effects of desloratadine on allergen prick tests after discontinuation.
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CLINICAL_TRIALS trial_result · 2009-12-23Clinical Trial Update: Hybrid SA RGP Center/S-H Skirt Daily Wear 90 Day Multicenter Study [NA]
A multicenter, 90-day clinical trial evaluating a Hybrid SA RGP Center/S-H Skirt daily wear contact lens is completed.
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CLINICAL_TRIALS trial_result · 2009-02-04Clinical Trial Update: Influence of Nutrition on Nasal and Bronchial Affliction in Patients With Allergy on Grass-Pollen [NA]
Completed clinical trial assessing the influence of nutrition on nasal and bronchial symptoms in individuals with grass-pollen allergy.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Phase II Efficacy Study of Aerosolized Recombinant Human IL-4 Receptor in Asthma [Phase 2]
Phase II efficacy study of an aerosolized recombinant human IL-4 receptor for asthma has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Mechanisms of Allergen Immunotherapy
NIAID-sponsored clinical trial investigating the mechanisms of allergen immunotherapy in asthma and hypersensitivity has completed.