Hypereosinophilic Syndrome
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression
This clinical trial update describes a longitudinal study of familial hypereosinophilia to characterize natural history and biomarkers of di…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Trial to Investigate Benralizumab in Children With Eosinophilic Diseases [Phase 3]
A Phase 3 clinical trial is recruiting to evaluate benralizumab in children with eosinophilic diseases including eosinophilic granulomatosis…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Dupilumab as Add-On Therapy for Hypereosinophilic Syndrome With Partial Clinical Response to Eosinophil-Depleting Biologic Agents [Phase 2]
Phase 2 trial evaluating dupilumab as add-on therapy for hypereosinophilic syndrome in patients with partial response to eosinophil-depletin…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Phase III Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES) [Phase 3]
A Phase III clinical trial is evaluating the efficacy and safety of benralizumab in patients with hypereosinophilic syndrome and is currentl…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Natural History of Hypereosinophilia and Hypereosinophilic Syndromes
A clinical trial sponsored by University Hospital Lille is studying the natural history of eosinophilia and hypereosinophilic syndromes; the…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders [Phase 2]
A Phase 2 clinical trial update for ruxolitinib in treating hypereosinophilic syndrome and other primary eosinophilic disorders; the study i…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: The Use of Machine Learning Techniques for the Differential Diagnosis Between Eosinophilic Granulomatosis With Polyangiitis and Hypereosinophilic Syndrome [NA]
A clinical trial update shows that recruitment is ongoing for a study using machine learning to differentiate between Eosinophilic Granuloma…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial [Phase 3]
A Phase 3 clinical trial evaluating depemokimab for hypereosinophilic syndrome is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: This Record Contains Information About the Mepolizumab Compassionate Use (CU) Product Activities: 104317: CU and Long-Term Access Study of Mepolizumab in HES. 201956:A Long-term Access Programme for Subjects With Severe Asthma 112562: Expanded Access for Patients With Hypereosinophilic
The document outlines compassionate-use and long-term access programs for mepolizumab in patients with hypereosinophilic syndrome, including…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Eosinophil Subpopulations in Eosinophilic-associated Diseases
A University of Florence trial update notes a study on eosinophil subpopulations in eosinophilic diseases. The study includes eosinophilic a…
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CLINICAL_TRIALS research · 2017-12-07Clinical Trial Update: Study to Evaluate Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects With Hypereosinophilic Syndrome [Phase 2]
Phase 2 clinical trial evaluating the safety and efficacy of dexpramipexole (KNS-760704) in hypereosinophilic syndrome; current status is no…
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CLINICAL_TRIALS research · 2009-09-15Clinical Trial Update: Study of STI571 in the Treatment of Patients With Idiopathic Hypereosinophilic Syndrome (HES) and Eosinophilic Leukemias [Phase 2]
This entry outlines a Phase 2 study evaluating imatinib (STI571) in patients with hypereosinophilic syndrome and eosinophilic leukemias, wit…