Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-03-04Clinical Trial Update: The Safety & Efficacy of Combination BMS-201038 (AEGR-733) & Ezetimibe vs. Monotherapy in Moderate Hypercholesterolemia [Phase 2]
Phase 2 trial results comparing the safety and efficacy of combining AEGR-733 (BMS-201038) with ezetimibe versus ezetimibe monotherapy in mo…
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CLINICAL_TRIALS trial_result · 2014-02-12Clinical Trial Update: MK0653C in High Cardiovascular Risk Patients With High Cholesterol (Switch Study)(MK-0653C-162) [Phase 3]
A Phase 3 trial evaluating MK0653C in high cardiovascular risk patients with high cholesterol has completed; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-01-29Clinical Trial Update: Cholesterol Lowering Treatment With Psyllium Husks and Isolated Soy Protein in Hypercholesterolemia [Phase 4]
Phase 4 clinical trial assessing the cholesterol-lowering effects of psyllium husks in combination with isolated soy protein in hypercholest…
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CLINICAL_TRIALS research · 2014-01-09Clinical Trial Update: Observational Study to Understand Patients' and Physicians' Attitudes to Statins in TurkeY
An observational study in Turkey assessed attitudes of patients and physicians toward statins in hypercholesterolemia; the trial sponsor is …
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CLINICAL_TRIALS trial_result · 2013-12-31Clinical Trial Update: Cardiovascular Risk Factors, Body Composition, Fitness Levels And Quality Of Life In Overweight And Obese 8-17 Year Olds [NA]
Completed clinical trial update examining cardiovascular risk factors, body composition, fitness levels, and quality of life in overweight a…
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CLINICAL_TRIALS trial_result · 2013-12-17Clinical Trial Update: The Efficacy and Safety of Atorva® 20mg Versus Lipitor® 20mg [Phase 4]
Phase 4 trial comparing Atorva 20 mg with Lipitor 20 mg in hypercholesterolemia to evaluate relative efficacy and safety.
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CLINICAL_TRIALS trial_result · 2013-12-17Clinical Trial Update: The Efficacy and Tolerability of Two Formulations of Atorvastatin In Korean Adult With Hypercholesterolemia [Phase 4]
Phase 4 trial comparing two formulations of atorvastatin in Korean adults with hypercholesterolemia showed data on efficacy and tolerability…
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CLINICAL_TRIALS trial_result · 2013-12-13Clinical Trial Update: Metabolism And Health Effects Of Citrus Limonoids in Hypercholesterolemic Humans [NA]
A completed clinical trial investigated the metabolism and health effects of citrus limonoids in adults with hypercholesterolemia.
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CLINICAL_TRIALS research · 2013-12-12Clinical Trial Update: Efficacy Study of Vitamin D and Statins to Treat Hypercholesterolemia [NA]
Clinical trial update on the efficacy of combining vitamin D with statins to treat primary hypercholesterolemia; current status is unknown.
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CLINICAL_TRIALS trial_result · 2013-12-10Clinical Trial Update: Safety, Tolerability, PK and PD of LGT209 in Healthy Volunteers and Patients With Hypercholesterolemia [Phase 1]
Phase 1 trial evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of LGT209 in healthy volunteers and patients with hyper…
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Study of Changes in Total Cholesterol Levels as a Function of Consuming a Supplement Designed to Improve Cardiovascular Health [NA]
This clinical trial update investigates whether a cardiovascular-health supplement changes total cholesterol levels. Details about the suppl…
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CLINICAL_TRIALS trial_result · 2013-11-13Clinical Trial Update: Supplementation of Alpha-linolenic Acid (ALA)-Rich Oil in Humans [EARLY_Phase 1]
A completed early-stage 1 trial evaluated supplementation with alpha-linolenic acid-rich oil in adults who are overweight or have hyperchole…
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CLINICAL_TRIALS trial_result · 2013-11-13Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Hypercholesterolemia. [NA]
A clinical trial update evaluating the efficacy and safety of rosuvastatin for hypercholesterolemia. The document provides no trial results …
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CLINICAL_TRIALS trial_result · 2013-10-29Clinical Trial Update: Intervention With Lupin Protein-enriched Foods in Hypercholesterolemic Subjects [NA]
A University of Jena–sponsored clinical trial evaluating lupin protein-enriched foods in adults with hypercholesterolemia has completed. The…
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CLINICAL_TRIALS research · 2013-10-28Clinical Trial Update: The Effect of Plant Sterols on Vascular Function [NA]
Clinical trial update on the effect of plant sterols on vascular function, sponsored by Unilever R&D. The excerpt notes the trial status as …
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FDA approval · 2013-10-25FDA Approved: ZOCOR — Supplemental Application (Organon LLC)
FDA approved a supplemental application for ZOCOR (simvastatin) submitted by Organon LLC to the existing NDA.
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CLINICAL_TRIALS trial_result · 2013-10-14Clinical Trial Update: Comparison of Pitavastatin With Atorvastatin in Increasing High Density Lipoprotein - Cholesterol (HDL-C) and Adiponectin in Patients With Dyslipidemia and Coronary Artery Disease (CAD) [Phase 4]
A Phase 4 study compares pitavastatin with atorvastatin to increase HDL-C and adiponectin in patients with dyslipidemia and coronary artery …
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CLINICAL_TRIALS trial_result · 2013-09-25Clinical Trial Update: Role of Milk Fat Globule Membranes in Dairy Foods: Health Effects in Humans [NA]
A completed clinical trial led by Uppsala University evaluated the health effects of milk fat globule membranes in dairy foods on people wit…
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CLINICAL_TRIALS trial_result · 2013-09-10Clinical Trial Update: Effect of a Community-based Nursing Intervention on Mortality in Chronically Ill Older Adults [NA]
Clinical trial update evaluating a community-based nursing intervention on mortality in chronically ill older adults. The study includes par…
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CLINICAL_TRIALS trial_result · 2013-08-27Clinical Trial Update: Flaxseed Compared With Placebo in Patients With Hypercholesterolemia [Phase 3]
Phase 3 trial comparing flaxseed with placebo in patients with familial or severe hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2013-08-21Clinical Trial Update: Effects of The Effects of Dietary Oils on Fasting Lipoprotein Lipids [NA]
A completed clinical trial assessed the impact of dietary oils on fasting lipoprotein lipids in individuals with hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2013-08-19Clinical Trial Update: Health Benefits of Whole Grain Oats in Population at Risk of Cardio-metabolic Disease [NA]
Completed clinical trial evaluating health benefits of whole grain oats in individuals at risk of cardiovascular disease and hypercholestero…
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CLINICAL_TRIALS trial_result · 2013-08-19Clinical Trial Update: Pharmacokinetic of Alirocumab SAR236553 (REGN727) Administered Subcutaneously at 3 Different Injection Sites in Healthy Subjects [Phase 1]
A Phase 1 pharmacokinetic study evaluating alirocumab (SAR236553/REGN727) given subcutaneously at three different injection sites in healthy…
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CLINICAL_TRIALS trial_result · 2013-08-05Clinical Trial Update: A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1) [Phase 3]
Phase 3 trial evaluating a fixed-dose combination of ezetimibe/atorvastatin versus separate ezetimibe and atorvastatin in patients with high…
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CLINICAL_TRIALS other · 2013-08-05Clinical Trial Update: A Safety Study of BMS-852927 in Subjects With Hypercholesterolemia [Phase 1]
Phase 1 safety study of the investigational agent BMS-852927 in adults with hypercholesterolemia has been terminated.