Hypercholesterolemia
📧 Sign up to get email alerts when something new happens for Hypercholesterolemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2014-08-19Clinical Trial Update: A Study to Evaluate the Efficacy of Valsartan/Simvastatin Combinations in Patients With Both Essential Hypertension and Hypercholesterolemia [Phase 3]
Phase 3 study evaluating the efficacy of valsartan/simvastatin combinations in patients with essential hypertension and hypercholesterolemia…
-
CLINICAL_TRIALS trial_result · 2014-08-15Clinical Trial Update: Effect of L. Reuteri NCIMB 30242 on Plasma Bile Acid Profile [Phase 2]
A Phase 2 trial evaluating the probiotic L. reuteri NCIMB 30242 and its impact on the plasma bile acid profile in adults with hypercholester…
-
CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction [Phase 4]
Phase 4 open-label trial comparing ezetimibe, niacin, and colestipol as adjunct therapy for lipid reduction; results were posted in 2014.
-
CLINICAL_TRIALS trial_result · 2014-08-07Clinical Trial Update: Effects of Nopales (Opuntia Spp.) on Lipoprotein Profile and Oxidative Stress in Moderately Hypercholesterolemic Adults [NA]
This clinical trial update reports completion of a study evaluating the effects of nopales (Opuntia spp.) on lipoprotein profile and oxidati…
-
CLINICAL_TRIALS trial_result · 2014-07-03Clinical Trial Update: The Effect of Atorvastatin on Endothelial Cell Dysfunction in Chronic Kidney Disease [Phase 4]
A Phase 4 trial evaluating atorvastatin for endothelial cell dysfunction in chronic kidney disease with hypercholesterolemia was terminated.…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
FDA approval · 2014-07-01FDA Approved: PRAVASTATIN SODIUM — Supplemental Application (CIPLA USA INC.)
The FDA approved a supplemental application for Pravastatin Sodium by Cipla USA Inc.
-
CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: Efficacy of a One-a-Day L. Reuteri NCIMB 30242 Probiotic Supplement Capsule [Phase 2]
A Phase 2 study assessed the efficacy of a daily Lactobacillus reuteri NCIMB 30242 probiotic capsule in adults with hypercholesterolemia; th…
-
CLINICAL_TRIALS research · 2014-06-25Clinical Trial Update: Cardiovascular Risk Factors And Intensive Dietary Counselling [NA]
An ongoing clinical trial sponsored by the Andalusian Regional Ministry of Health investigates whether intensive dietary counseling can infl…
-
CLINICAL_TRIALS trial_result · 2014-06-11Clinical Trial Update: Efficacy and Safety of Fluvastatin Sodium Extended Release Tablets 80 mg Once Daily in Chinese Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia [Phase 4]
Phase 4 trial evaluating the efficacy and safety of fluvastatin sodium extended-release 80 mg once daily in Chinese patients with primary hy…
-
FDA label_change · 2014-05-22FDA Approved: COLESTID — Supplemental Application (Pharmacia & Upjohn Company LLC)
The FDA approved a supplemental labeling application for COLESTID (colestipol hydrochloride) submitted by Pharmacia & Upjohn Company LLC to …
-
FDA approval · 2014-05-22FDA Approved: COLESTID — Supplemental Application (Pharmacia & Upjohn Company LLC)
The FDA approved a supplemental application for COLESTID (colestipol hydrochloride) submitted by Pharmacia & Upjohn Company LLC.
-
CLINICAL_TRIALS trial_result · 2014-05-20Clinical Trial Update: The Effect of a Red Rice and Olive Extract Nutrition Supplement on Cholesterol Levels in Patients With Metabolic Syndrome [Phase 4]
Phase 4 trial completed evaluating whether a red rice and olive extract nutrition supplement lowers cholesterol in patients with metabolic s…
-
CLINICAL_TRIALS trial_result · 2014-05-16Clinical Trial Update: Influence of OATP1B1 and BRCP Genotype on Rosuvastatin PK, PD and Lipidomics in Hyperlipidemic Patients [Phase 4]
Phase 4 study assessing how OATP1B1 and BRCP genotypes influence rosuvastatin pharmacokinetics, pharmacodynamics, and lipidomics in hypercho…
-
CLINICAL_TRIALS trial_result · 2014-05-15Clinical Trial Update: Metformin in Preventing Androgen Deprivation Therapy Induced Insulin Resistance and Metabolic Syndrome [Phase 2]
Phase 2 trial evaluating metformin to prevent androgen deprivation therapy-induced insulin resistance and metabolic syndrome. The study stat…
-
CLINICAL_TRIALS trial_result · 2014-04-25Clinical Trial Update: Niacin (+) Laropiprant (TREDAPTIVE) Re-examination Study (MK-0524A-119)
The Niacin/laropiprant re-examination study (TREDAPTIVE) for hypercholesterolemia and mixed dyslipidemia was terminated, with results posted…
-
CLINICAL_TRIALS trial_result · 2014-04-09Clinical Trial Update: Investigation of the Effect of Dietary Nitrate Treatment on Endothelial Function and Platelet Reactivity in Hypercholesterolemics. [Phase 1]
A Phase 1 clinical trial assessing whether dietary nitrate improves endothelial function and modulates platelet reactivity in adults with hy…
-
CLINICAL_TRIALS trial_result · 2014-04-02Clinical Trial Update: TACTICS (Targeting Adherence to Cholesterol-lowering Therapy to Improve Control Study) [NA]
This clinical trial update indicates that the TACTICS study on adherence to cholesterol-lowering therapy for hypercholesterolemia has comple…
-
FDA approval · 2014-03-20FDA Approved: NIACIN — Original Application (Lupin Pharmaceuticals, Inc.)
FDA approved Lupin Pharmaceuticals' original abbreviated new drug application for NIACIN, a generic nicotinic acid product.
-
CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: A Multicenter, Active and Placebo-controlled Study of Enteric Coated Sevelamer in Patients With Mild to Moderate Hypercholesteremia [Phase 2]
A Phase 2 multicenter trial evaluating enteric-coated sevelamer in patients with mild to moderate hypercholesterolemia has completed.
-
CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: Blood Lipid-lowering Effect of Brown Alga Ecklonia Cava [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating the blood lipid-lowering effect of Ecklonia cava extract in adults with hypercholesterolemia has complet…
-
CLINICAL_TRIALS trial_result · 2014-03-17Clinical Trial Update: Alternative Options to Minimize Niacin-Induced Flushing [NA]
A completed clinical trial evaluated alternative strategies to minimize niacin-induced flushing in people with high cholesterol; results wer…
-
CLINICAL_TRIALS trial_result · 2014-03-14Clinical Trial Update: Efficacy and Safety of Extended Release (ER) Niacin/Laropiprant When Added to Ongoing Lipid-Modifying Therapy in Patients With High Cholesterol or Abnormal Lipid Levels (MK-0524A-133) [Phase 3]
Phase 3 trial evaluating MK-0524A (extended-release niacin/laropiprant) added to ongoing lipid-modifying therapy in patients with primary hy…
-
CLINICAL_TRIALS trial_result · 2014-03-13Clinical Trial Update: Phytosterol Supplementation and Cardiovascular Risk [NA]
This clinical trial update reports the completion of a study assessing phytosterol supplementation for cardiovascular risk in individuals wi…
-
CLINICAL_TRIALS trial_result · 2014-03-11Clinical Trial Update: Effect of Beta-Glucan on Cholesterol Lowering [NA]
A completed clinical trial evaluated beta-glucan for cholesterol lowering in adults with hypercholesterolemia. Results were posted on 2014-0…
-
CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: Long Term Efficacy and Tolerability of a Nutraceutical Combination (Red Yeast Rice, Policosanols and Berberine) in Low-moderate Risk Hypercholesterolemic Patients: a Double-blind, Placebo Controlled Study [Phase 4]
This Phase 4 trial evaluated the long-term efficacy and tolerability of a nutraceutical combination of red yeast rice, policosanols, and ber…