Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2015-04-23Clinical Trial Update: Multiple-Dose Safety Study Of RN316 For TheTreatment Of Hypercholesterolemia [Phase 1]
Phase 1 multiple-dose safety study of the investigational drug RN316 for hypercholesterolemia/dyslipidemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-04-22Clinical Trial Update: Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone. [Phase 3]
Phase 3 study comparing the anti-atherosclerotic effect of torcetrapib added to atorvastatin versus atorvastatin alone has completed.
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CLINICAL_TRIALS trial_result · 2015-04-22Clinical Trial Update: Nutraceutical Combination in Patients With Low-grade Systemic Inflammation [Phase 4]
Phase 4 clinical trial update on a nutraceutical combination in patients with low-grade systemic inflammation, including those with atherosc…
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FDA approval · 2015-04-15FDA Approved: PRAVASTATIN SODIUM — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for Pravastatin Sodium submitted by Aurobindo Pharma Limited, approving this generic statin product.
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CLINICAL_TRIALS research · 2015-04-15Clinical Trial Update: Relationship Between CETP Deficiency and Atherosclerosis in Patients With Hyperalphalipoproteinemia
This clinical trial update describes investigating whether CETP deficiency influences atherosclerosis in patients with hyperalphalipoprotein…
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CLINICAL_TRIALS trial_result · 2015-04-08Clinical Trial Update: Effects of Vitamin D on Lipids [NA]
This document provides an update on a completed clinical trial evaluating whether vitamin D supplementation affects lipid levels in people w…
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CLINICAL_TRIALS trial_result · 2015-04-07Clinical Trial Update: Effects of Dietary Antioxidants to Prevent Cardiovascular Disease [Phase 2]
Phase 2 clinical trial update examining whether dietary antioxidants can prevent cardiovascular disease; the study has completed, and includ…
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CLINICAL_TRIALS research · 2015-04-07Clinical Trial Update: Systematic Management of High Cholesterol Utilizing Computer Monitoring [NA]
This entry notes the completion of a clinical trial evaluating systematic management of high cholesterol using computer monitoring. The tria…
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Atorvastatin for at Least 4 Weeks. [Phase 4]
Phase 4 trial investigating the effect of WelChol tablets (colesevelam) on cholesterol in patients already taking atorvastatin for at least …
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Simvastatin for at Least 4 Weeks. [Phase 4]
This Phase 4 clinical trial evaluated WelChol (cholestyramine) tablets for lowering cholesterol in patients who had been taking simvastatin …
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: Study to Compare Welchol and TriCor to TriCor Alone in Patients With High Cholesterol [Phase 4]
A Phase 4 study comparing Welchol (colesevelam) plus TriCor (fenofibrate) to TriCor alone in patients with hypercholesterolemia and hyperlip…
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Pravastatin for at Least 4 Weeks. [Phase 4]
Phase 4 trial evaluating the effect of WelChol (colesevelam) on cholesterol levels in patients who have been taking pravastatin for at least…
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CLINICAL_TRIALS trial_result · 2015-04-01Clinical Trial Update: Plaque REgression With Cholesterol Absorption Inhibitor or Synthesis Inhibitor Evaluated by IntraVascular UltraSound [Phase 4]
A Phase 4 clinical trial evaluated plaque regression using either a cholesterol absorption inhibitor or a cholesterol synthesis inhibitor, a…
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CLINICAL_TRIALS trial_result · 2015-03-17Clinical Trial Update: LIpid Lowering With Highly Potent Statins in Hyperlipidaemia With Type 2 Diabetes patiENts [NA]
A completed clinical trial evaluating lipid-lowering with highly potent statins in patients with hypercholesterolemia and type 2 diabetes, w…
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CLINICAL_TRIALS trial_result · 2015-03-17Clinical Trial Update: A Human Trial to Assess the Low Density Lipoprotein Cholesterol (LDL-C) Lowering Effect of Soy [NA]
A clinical trial evaluated whether soy can lower LDL cholesterol in individuals with hypercholesterolemia and cardiovascular disease; the st…
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Effect of Apples on cardioVascular Risk And Gut Health [NA]
A completed clinical trial from the University of Reading examined whether apple consumption affects cardiovascular risk markers and gut hea…
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CLINICAL_TRIALS trial_result · 2015-03-03Clinical Trial Update: Effect of Oats on Lipid Profile [NA]
This entry reports a completed clinical trial evaluating how oats affect the lipid profile in adults with mild hypercholesterolemia.
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CLINICAL_TRIALS trial_result · 2015-03-02Clinical Trial Update: MK0859 Dose-Ranging Study (0859-003) [Phase 2]
Merck's Phase 2 dose-ranging study of MK0859 (NCT00325455) for hypercholesterolemia and mixed hyperlipidemia has been terminated.
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: A Study of MK0859 in Patients With Primary Hypercholesterolemia or Mixed Hyperlipidemia (MK-0859-011)(COMPLETED) [Phase 1]
The Phase 1 study MK-0859-011 in patients with primary hypercholesterolemia or mixed hyperlipidemia has completed; this update confirms the …
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CLINICAL_TRIALS trial_result · 2015-02-09Clinical Trial Update: Tailored Communication to Reduce Cardiovascular Risk [NA]
This clinical trial update reports completed results from a Northwestern University study on tailored communication strategies to reduce car…
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CLINICAL_TRIALS research · 2015-01-27Clinical Trial Update: Ascending Multi-dose Study of REGN727(SAR236553) With and Without Concomitant Atorvastatin [Phase 1]
Phase 1 ascending multi-dose trial of REGN727 (alirocumab) with and without atorvastatin for hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: Serum Cholesterol Reduction Efficacy of Biscuit With Plant Stanol Ester [NA]
A completed clinical trial evaluated the effect of a biscuit containing plant stanol ester on serum cholesterol in individuals with dyslipid…
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CLINICAL_TRIALS research · 2015-01-08Clinical Trial Update: Statin Therapy to Improve Medication Adherence [Phase 1]
Phase 1 clinical trial evaluating whether statin therapy can improve medication adherence in hypercholesterolemia has completed.
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: A 4-week, Randomized, Placebo-Controlled, Double-Blind, Efficacy and Safety Study of HS-25 in Adults With Primary Hypercholesterolemia [Phase 2]
The document reports the completion of a 4-week, randomized, placebo-controlled, double-blind Phase 2 trial evaluating HS-25 for efficacy an…
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Cholesterol-lowering Effects of Plant Stanol Ester [NA]
A completed clinical trial sponsored by Raisio Group evaluated the cholesterol-lowering effects of plant stanol ester.