Hypercholesterolemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS other · 2016-05-12Clinical Trial Update: Can Cholesterol Lowering Drugs Influence Circulating Omega-3 Fatty Acid Levels [NA]
A completed clinical trial evaluated whether cholesterol-lowering drugs influence circulating omega-3 fatty acid levels. The study was spons…
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: A Comparison of the Effects on Cardiovascular Risk Factors of Korean and American Dietary Profiles [NA]
This completed clinical trial compared the effects of Korean versus American dietary profiles on cardiovascular risk factors in individuals …
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CLINICAL_TRIALS trial_result · 2016-05-05Clinical Trial Update: Dietary Intervention Study in Children (DISC) [Phase 3]
A Phase 3 dietary intervention trial in children (DISC) sponsored by the NHLBI has completed.
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CLINICAL_TRIALS research · 2016-05-05Clinical Trial Update: CEntralized Pan-Russian Survey of tHE Undertreatment of hypercholeSterolemia II (CEPHEUS II)
This document reports the completion of CEPHEUS II, a centralized Pan-Russian survey evaluating undertreatment of dyslipidemia, including hy…
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CLINICAL_TRIALS research · 2016-04-18Clinical Trial Update: Effect of Diabetes Mellitus on Cholesterol Metabolism [NA]
Clinical trial update examining the effect of diabetes mellitus on cholesterol metabolism; completed with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-04-12Clinical Trial Update: Phase 2 Dose-Ranging Efficacy and Safety Trial of SCH 900271 in Participants With Primary Hypercholesterolemia or Mixed Hyperlipidemia (P05675) [Phase 2]
Phase 2 dose-ranging trial evaluating SCH 900271 in primary hypercholesterolemia and mixed hyperlipidemia completed with posted results.
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated Hypertriglyceridemia [Phase 4]
Phase 4 clinical trial evaluating omega-3 fatty acids (Lovaza) for hypertriglyceridemia associated with second-generation antipsychotics. Re…
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CLINICAL_TRIALS trial_result · 2016-04-01Clinical Trial Update: MK-0524B Lipid Study (MK-0524B-063) [Phase 3]
A Phase 3 clinical trial of MK-0524B for primary hypercholesterolemia and mixed dyslipidemia has completed, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Worksites, Occupational Nurses and Cholesterol Change
A completed NHLBI trial update examining cholesterol changes in the workplace setting among individuals with hypercholesterolemia and cardio…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Pawtucket Heart Health Program
The Pawtucket Heart Health Program clinical trial sponsored by the NHLBI has completed. The study focused on cardiovascular health condition…
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CLINICAL_TRIALS trial_result · 2016-03-14Clinical Trial Update: High Potency Statins and Acute Kidney Injury
The document reports the completed results of an observational study examining whether high-potency statins are associated with acute kidney…
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CLINICAL_TRIALS trial_result · 2016-02-29Clinical Trial Update: Sex Steroids, Obesity and Lipids in Adolescent Females
NHLBI reports a completed clinical trial update examining how sex steroids relate to obesity and lipid levels in adolescent females, with im…
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Cholesterol Reduction in Seniors Program (CRISP) [Phase 2]
This is an update for the Cholesterol Reduction in Seniors Program (CRISP), a Phase 2 trial evaluating cholesterol-lowering strategies in se…
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CLINICAL_TRIALS research · 2016-02-18Clinical Trial Update: Population-Based Modeling of Cholesterol Lowering in the United States
A completed population-based modeling study assessing how cholesterol-lowering strategies may impact cardiovascular risk in the United State…
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Postprandial Lipemia and Endothelial Function in ACCORD- Ancillary to ACCORD
Clinical trial update on the ACCORD ancillary study examining postprandial lipemia and endothelial function. The study is completed.
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Evaluation of Childhood Blood Pressure and Lipid Screening
Completed clinical trial evaluating screening for blood pressure and lipids in children. The study assessed pediatric screening for cardiova…
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Evaluation of Cholesterol Education for At-Risk Children
NHLBI-sponsored clinical trial evaluating cholesterol education for at-risk children has completed. The update does not include trial result…
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Genetics of Low Density Lipoprotein Subclasses in Hypercholesterolemia
A completed University of Washington clinical trial update examining how genetic variation influences LDL particle subclasses in individuals…
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Dietary Treatment of Hyperlipidemia in Women vs. Men
Completed clinical trial evaluating dietary treatment of hyperlipidemia in women versus men.
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CLINICAL_TRIALS research · 2016-02-03Clinical Trial Update: Effect of Plant Sterol Enriched Milk on Plasma Lipid Levels of Humans Breast-fed During Infancy [NA]
A clinical trial evaluating whether plant sterol-enriched milk affects plasma lipid levels in humans breast-fed during infancy.
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN) [Phase 3]
Phase 3 trial update (ODYSSEY JAPAN) evaluating the efficacy and safety of alirocumab in patients with heterozygous familial hypercholestero…
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CLINICAL_TRIALS trial_result · 2016-01-27Clinical Trial Update: Actual Use Trial of Atorvastatin Calcium 10 mg [Phase 3]
Phase 3 actual-use trial of atorvastatin calcium 10 mg completed; results posted in 2016.
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FDA approval · 2016-01-27FDA Approved: FLUVASTATIN SODIUM — Original Application (Teva Pharmaceuticals USA, Inc.)
FDA approved Teva's generic fluvastatin sodium as an original ANDA, enabling its use to treat hyperlipidemia and reduce cardiovascular risk.
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: Effects of α-linolenic Acid Supplementation on Hemostasis in Nondiabetic and Hypercholesterolemic Subjects [Phase 3]
A Phase 3 clinical trial assessing whether alpha-linolenic acid supplementation affects hemostasis in nondiabetic, hypercholesterolemic adul…
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CLINICAL_TRIALS research · 2016-01-20Clinical Trial Update: EFFECTS OF CARDICHOL, AN HERBAL DIETARY SUPPLEMENT, IN MODERATE HYPERCHOLESTEROLEMIA [NA]
This document reports a clinical trial update for Cardichol, an herbal dietary supplement, being studied for moderate hypercholesterolemia. …