Hyperandrogenism
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Evaluating the Influence of Diet-induced Weight Loss on Fat (Adipose) Tissue's Insulin Sensitivity and Testosterone Synthesis in Women With Overweight or Obesity, Insulin Resistance, and Hyperandrogenemia [NA]
This clinical trial update describes a study examining whether diet-induced weight loss alters adipose tissue insulin sensitivity and testos…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Inositol Supplementation to Treat PCOS (INSUPP-PCOS) [Phase 2]
Phase 2 clinical trial INSUPP-PCOS studying inositol supplementation for Polycystic Ovary Syndrome has completed.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Combined Use of Machine Learning and Metabolomics to Improve the Diagnosis and Management of Hyperandrogenism
A clinical trial update describes a study that combines machine learning and metabolomics to improve diagnosis and management of hyperandrog…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Cardiovascular and Endothelial Markers During OGTT Before and at Six and Twelve Months Post-treatment in Women With PCOS
This is a registered clinical trial evaluating cardiovascular and endothelial markers during an oral glucose tolerance test in women with po…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism? [EARLY_Phase 1]
This ClinicalTrials.gov entry describes an early-phase 1 study investigating whether spironolactone can normalize sleep-wake luteinizing hor…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Hyperandrogenemia and Altered Day-night LH Pulse Patterns [EARLY_Phase 1]
An early-phase 1 clinical trial sponsored by the University of Virginia is investigating hyperandrogenism and altered day-night LH pulse pat…
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CLINICAL_TRIALS other · 2024-10-09Clinical Trial Update: Acupuncture or Metformin for Insulin Resistance in Women With PCOS [Phase 2]
A Phase 2 clinical trial is evaluating acupuncture versus Metformin for insulin resistance in women with Polycystic Ovary Syndrome and is cu…
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CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: FEmale Metabolic Risk and Androgens: an Irish Longitudinal (FEMAIL) Study
This entry describes the FEmale Metabolic Risk and Androgens: an Irish Longitudinal (FEMAIL) Study, an Irish observational trial led by the …
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin Resistant [Phase 2]
Phase 2 trial evaluating metformin plus clomiphene citrate versus placebo plus clomiphene citrate for induction of ovulation in insulin-resi…
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CLINICAL_TRIALS trial_result · 2021-01-08Clinical Trial Update: Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone [NA]
A completed clinical trial evaluating how metformin influences the GnRH pulse generator's sensitivity to estradiol and progesterone in women…
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: The Effect of Ibuprofen on Women With PCOS. [Phase 2]
Phase 2 clinical trial evaluating the effect of ibuprofen on women with polycystic ovary syndrome (PCOS) and hyperandrogenism, with an addit…
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CLINICAL_TRIALS trial_result · 2018-11-29Clinical Trial Update: Comparison of Metformin and Pioglitazone in Regulating Menstrual Irregularities and Hyperandrogenism [Phase 1, Phase 2]
A clinical trial comparing metformin and pioglitazone for regulating menstrual irregularities and hyperandrogenism.
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CLINICAL_TRIALS withdrawal · 2018-07-19Clinical Trial Update: Effect of Short Term Adrenal Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess [EARLY_Phase 1]
An early phase 1 trial studying short-term adrenal suppression to reduce androgen overproduction in overweight girls with androgen excess ha…
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CLINICAL_TRIALS withdrawal · 2018-07-19Clinical Trial Update: Effect of Longer-term Adrenal Suppression Using Low Dose Hydrocortisone on Androgen Overproduction [EARLY_Phase 1]
A Phase EARLY_PHASE1 trial evaluating longer-term adrenal suppression with low-dose hydrocortisone to reduce androgen overproduction has bee…
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CLINICAL_TRIALS withdrawal · 2018-07-19Clinical Trial Update: Effect of Short Term Ovarian Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess [EARLY_Phase 1]
EARLY_PHASE1 clinical trial evaluating short-term ovarian suppression to reduce androgen overproduction in overweight girls with androgen ex…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Effects of Androgen Blockade on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone [NA]
A terminated clinical trial tested whether blocking androgens affects the GnRH pulse generator's sensitivity to suppression by estradiol and…
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: Bariatric Surgery, Hormones, and Quality of Life [NA]
A completed clinical trial from Linköping University studying bariatric surgery and its effects on hormonal disturbances and quality of life…
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CLINICAL_TRIALS trial_result · 2017-03-23Clinical Trial Update: Circulating Androgen Levels Are Not Affected by the Administration of Vaginal Micronized Progesterone for Withdrawal Bleeding in Patients With Polycystic Ovarian Syndrome [NA]
A completed clinical trial evaluating vaginal micronized progesterone for withdrawal bleeding in women with PCOS found that circulating andr…
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CLINICAL_TRIALS research · 2016-03-09Clinical Trial Update: Ultrasound Three-dimensional Characterization of Ovarian Morphology in Women With Polycystic Ovary Syndrome (PCOS) [NA]
This clinical trial update describes a study using three-dimensional ultrasound to characterize ovarian morphology in women with Polycystic …
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CLINICAL_TRIALS trial_result · 2016-01-13Clinical Trial Update: Effect of a Commonly Used Antibiotic, Doxycycline, in Women With Polycystic Ovarian Syndrome [Phase 3]
Phase 3 trial evaluating doxycycline in women with polycystic ovary syndrome, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2015-04-08Clinical Trial Update: Meal Timing on Glucose Metabolism and Hyperandrogenism in Lean Women With Polycystic Ovary Syndrome [NA]
Clinical trial update examining how meal timing affects glucose metabolism and hyperandrogenism in lean women with polycystic ovary syndrome…
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CLINICAL_TRIALS research · 2014-11-21Clinical Trial Update: Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by Antioxidants [Phase 4]
Phase 4 trial evaluating coagulation and lipoperoxidation in women using combined oral contraceptives, with potential correction by antioxid…
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CLINICAL_TRIALS research · 2013-11-18Clinical Trial Update: Effects of Androgen Administration on Inflammation in Normal Women [NA]
A completed Mayo Clinic clinical trial evaluating the effect of androgen administration on inflammatory markers in women with hyperandrogeni…
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CLINICAL_TRIALS trial_result · 2013-11-06Clinical Trial Update: Presentations of Hyperandrogenic Phenotypes in Taiwanese Women
This clinical trial update reports presentations of hyperandrogenic phenotypes in Taiwanese women, highlighting associations with polycystic…
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CLINICAL_TRIALS research · 2010-08-06Clinical Trial Update: Ethinyl Estradiol and Cyproterone Acetate in Irregular Menstruation [Phase 4]
This clinical trial registry entry describes a Phase 4 study of a combined ethinyl estradiol and cyproterone acetate regimen for irregular m…