Hyper-ige Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis [Phase 1]
This clinical trial update reports on evaluating the safety and tolerability of baricitinib in patients with Hyper-IgE syndrome due to STAT3…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation Disorders
A National Institute of Allergy and Infectious Diseases trial update describes establishing fibroblast-derived cell lines from skin biopsies…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Screening Protocol for Genetic Diseases of Allergic Inflammation
Completed clinical trial update describing a screening protocol for genetic diseases involved in allergic inflammation.
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases [Phase 1, Phase 2]
This clinical trial update describes an early-phase study evaluating sequential cadaveric lung transplantation followed by bone marrow trans…
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CLINICAL_TRIALS trial_result · 2020-06-30Clinical Trial Update: Safety, Tolerability, and Immunogenicity of One Dose of NDV 3A Vaccine in People With STAT3-Mutated Hyper-IgE Syndrome [Phase 2]
Phase 2 trial assessing safety, tolerability, and immunogenicity of a single dose of the NDV 3A vaccine in individuals with STAT3-mutated Hy…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Omalizumab to Treat Hyper-IgE (Job's) Syndrome [Phase 1]
Phase 1 trial of omalizumab for Hyper-IgE Syndrome (Job's Syndrome) has been completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Posaconazole to Treat Invasive Fungal Infections [Phase 3]
Phase 3 trial of posaconazole for invasive fungal infections has completed, involving patients with chronic granulomatous disease and Hyper-…
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CLINICAL_TRIALS research · 2014-08-29Clinical Trial Update: NFIL3-induced Pathological Enhancement of IgE Class Switch Recombination in Hyper-IgE Syndrome
Clinical trial update examining NFIL3-induced enhancement of IgE class switch recombination in Hyper-IgE syndrome.
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CLINICAL_TRIALS trial_result · 2013-02-04Clinical Trial Update: Effect of Ranitidine on Hyper-IgE Recurrent Infection (Job's) Syndrome [Phase 2]
A Phase 2 trial evaluating ranitidine for JOB's syndrome (Hyper-IgE recurrent infection syndrome) was terminated; results were posted in 201…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Diagnostic Effectiveness of Virtual Bronchoscopy [Phase 1]
Phase 1 clinical trial update evaluating the diagnostic effectiveness of virtual bronchoscopy for lung-related diseases.
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CLINICAL_TRIALS research · 2008-03-04Clinical Trial Update: Learning and Behavior Problems in Children With Chronic Granulomatous Disease and Related Disorders
This completed clinical trial update investigates learning and behavior problems in children with chronic granulomatous disease and related …