Hpv-positive Oropharyngeal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: CUE-101with Pembrolizumab for LA-HPV+HNSCCs [Phase 2]
This ClinicalTrials.gov entry describes a Phase 2 trial evaluating CUE-101 in combination with Pembrolizumab for locally advanced, HPV-posit…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Risk-adapted Therapy in HPV-positive Oropharyngeal Cancer Using Circulating Tumor (ct) HPV DNA Profiling (ReACT 2.0) [Phase 2]
This Clinical Trials update outlines a Phase 2 study (ReACT 2.0) evaluating risk-adapted therapy guided by circulating tumor HPV DNA profili…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Reduced Elective Nodal and CTV Dose for HPV+ Oropharyngeal Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial update proposes reducing elective nodal and clinical target volume doses for HPV-positive oropharyngeal squamous ce…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer [Phase 2]
A Phase 2 trial is testing adaptive de-intensified radiotherapy guided by circulating tumor DNA in HPV-positive oropharyngeal cancer, and th…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Trial of De-Intensified Post-operative Chemoradiation Following Robotic Surgery for HPV-positive Oropharyngeal Cancer [Phase 2]
Phase 2 clinical trial evaluating de-intensified post-operative chemoradiation after robotic surgery for HPV-positive oropharyngeal squamous…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC) [Phase 2]
Phase 2 clinical trial evaluating sacituzumab govitecan in combination with cetuximab for head and neck squamous cell cancers is currently r…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED) [Phase 2]
A single-arm Phase II trial (SAVED) in p16-positive oropharyngeal cancer evaluating selective dose de-escalation of nodal and primary-site r…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: ctDNA Liquid Biopsy for Early Assessment of Residual Disease in HPV-associated Head and Neck Cancer (Clear-HPVca)
A completed clinical study (Clear-HPVca) evaluated ctDNA liquid biopsy for early assessment of residual disease in HPV-positive oropharyngea…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL) [Phase 2]
Phase 2 clinical trial evaluating adjuvant therapy tailored by residual circulating tumor DNA in patients with HPV-positive oropharyngeal sq…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)
This clinical trial update describes a study using HPV DNA testing to detect HPV-related oropharyngeal cancer; sponsored by Memorial Sloan K…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: ctHPVDNA in HPV Positive Squamous Cell Carcinoma of the Oropharynx [NA]
Clinical trial update for ctHPVDNA in HPV-positive oropharyngeal squamous cell carcinoma; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE) [NA]
A clinical trial (DE-RADIATE) is investigating de-escalation of radiation dose for HPV-positive oropharyngeal squamous cell carcinoma guided…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study [Phase 2]
This is a Phase 2 clinical trial (ReACT) evaluating risk-adapted therapy guided by circulating tumor HPV DNA in HPV-associated and HPV-posit…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial) [Phase 2]
The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0) is a Phase 2 study evaluating robotic transo…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Adjuvant Treatment Deintensification After Transoral Surgery for Human Papillomavirus-Positive Squamous Cell Carcinoma [NA]
This entry reports on a clinical trial investigating deintensification of adjuvant therapy after transoral surgery for HPV-positive orophary…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx
This clinical trial update notes ongoing recruitment for a study evaluating de-escalated radiation therapy in HPV-positive oropharyngeal squ…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: A Phase I/IIa Clinical Trial to Investigate BVAC-E6E7 in Subjects with HPV Positive HNSCC. [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2a study evaluating BVAC-E6E7 in HPV-positive head and neck squamous cell carcinoma, with the t…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Safety and Efficacy of VB10.16 and Pembrolizumab in Patients with Head-Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating VB10.16 in combination with pembrolizumab for HPV-positive oropharyngeal squamous cell carcinoma and head-and-n…
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CLINICAL_TRIALS research · 2024-09-03Clinical Trial Update: Surgery and Reducing Ionizing Radiation of the Unknown Primary [Phase 2]
A Phase 2 clinical trial update describes evaluating surgical management with reduced ionizing radiation for unknown primary head and neck c…
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer [Phase 2]
A Phase 2 trial is testing a less intensive radiation regimen with chemotherapy for low-risk HPV-positive oropharyngeal cancer and is curren…