Records containing: Homozygous Familial Hypercholesterolemia
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CLINICAL_TRIALS study record update · 2026-04-06The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository
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CLINICAL_TRIALS study record update · 2026-03-27Phase 3 Study to Evaluate the Efficacy and Safety of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)
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CLINICAL_TRIALS study record update · 2026-03-20Phase 3 Single-Arm Open-Label Study to Evaluate the Efficacy and Safety of Zodasiran in Adolescent Participants (Age 12 to <18 Years) With Homozygous Familial Hypercholesterolemia (SPRUCE)
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CLINICAL_TRIALS study record update · 2025-12-18HoFH, the International Clinical Collaborators - A Global HoFH Data-sharing Platform
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CLINICAL_TRIALS study record update · 2025-12-15A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia
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CLINICAL_TRIALS study record update · 2025-10-10Phase 2 Study to Evaluate the Safety and Efficacy of ARO-ANG3 in Subjects With Homozygous Familial Hypercholesterolemia (HOFH)
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CLINICAL_TRIALS study record update · 2025-09-05A Single-Arm, Open-Label, Phase II Clinical Study to Evaluate the Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia
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CLINICAL_TRIALS study record update · 2025-08-21A Multicenter, Single Arm, Open Label Phase II Clinical Study Evaluating the Long-term Efficacy and Safety of SHR-1918 in Homozygous Familial Hypercholesterolemia Patients
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CLINICAL_TRIALS study record update · 2025-03-25Safety and Effectiveness of Evinacumab for the Treatment of Homozygous Familial Hypercholesterolemia in a Real Life Setting in Canada
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CLINICAL_TRIALS study record update · 2024-12-09A Clinical Study for the Safety and Efficacy of Intravenous Infusion of NGGT006 in Treatment of Homozygous Familial Hypercholesterolemia With LDLR Mutations
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CLINICAL_TRIALS study record update · 2024-04-30An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia
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CLINICAL_TRIALS study record update · 2024-03-12LOWER: Lomitapide Observational Worldwide Evaluation Registry
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CLINICAL_TRIALS study record update · 2024-03-06An Open-label Extension Trial of the Phase III Lipid-lowering Trials to Assess the Effect of Long Term Dosing of Inclisiran Given as Subcutaneous Injections in Subjects With High Cardiovascular Risk and Elevated LDL-C
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CLINICAL_TRIALS study record update · 2023-08-09Phase 2b/3 Study to Assess the Efficacy and Safety of IBI306 in Subjects With Homozygous Familial Hypercholesterolemia.
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CLINICAL_TRIALS study record update · 2023-06-07A Three-Part, Single-Arm, Open-Label Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia
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CLINICAL_TRIALS study record update · 2023-03-29Randomized, Open-Label, Cross-Over, Phase 3 Study to Evaluate the Efficacy and Safety of LIB003 With Evolocumab in Homozygous Familial Hypercholesterolemia Patients on Stable Lipid-Lowering Therapy
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CLINICAL_TRIALS study record update · 2023-03-02A Phase 2 Study to Evaluate the Safety and Efficacy of PCSK9 Inhibitor AK102 in Patients With Homozygous Familial Hypercholesterolemia (HoFH)
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CLINICAL_TRIALS study record update · 2022-11-10A Two-Part (Double-Blind Placebo Controlled/Open-Label) Multicenter Study to Evaluate Safety, Tolerability, and Efficacy of Inclisiran in Subjects With Homozygous Familial Hypercholesterolemia (Hofh) (ORION-5)
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CLINICAL_TRIALS study record update · 2021-06-29A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Alirocumab in Patients With Homozygous Familial Hypercholesterolemia
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CLINICAL_TRIALS study record update · 2021-05-24Study of cardiovAscular Contrasted Phenotypes in Patients With FamIliaI hypercholesteRolemia
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CLINICAL_TRIALS study record update · 2021-05-18A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia
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CLINICAL_TRIALS study record update · 2020-05-18An Open-Label, Single-Arm, Multicenter Pilot Study to Evaluate Safety, Tolerability, and Efficacy of ALN-PCSSC in Subjects With Homozygous Familial Hypercholesterolemia (HoFH)
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CLINICAL_TRIALS study record update · 2019-12-09An Open-Label, Single-Arm, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Single and Multiple Doses of REGN1500 in Patients With Homozygous Familial Hypercholesterolemia
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CLINICAL_TRIALS study record update · 2019-05-23HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia
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CLINICAL_TRIALS study record update · 2018-12-03A Phase 2 Open-Label Study to Assess the Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of ISIS 703802 (AKCEA-ANGPTL3-LRx) Administered Subcutaneously to Patients With Homozygous Familial Hypercholesterolemia (HoFH)