HIV Infections
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CLINICAL_TRIALS trial_result · 2011-05-24Clinical Trial Update: Mefloquine Prophylaxis in HIV-1 Individuals: a Randomized Placebo-controlled Trial [NA]
A completed randomized, placebo-controlled trial evaluating mefloquine as prophylaxis in HIV-1 individuals.
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CLINICAL_TRIALS trial_result · 2011-04-25Clinical Trial Update: An International Study to Evaluate Recombinant Interleukin-2 in HIV Positive Patients Taking Anti-retroviral Therapy [Phase 3]
Phase 3 trial assessing recombinant interleukin-2 in HIV-positive patients on antiretroviral therapy has completed with posted results.
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CLINICAL_TRIALS trial_result · 2011-04-14Clinical Trial Update: A Pilot Study to Compare the Antiviral and Immunologic Effects of Stavudine ( d4T ) Versus Placebo in Subjects With Evidence of Recent HIV Infection. [NA]
This pilot trial compared the antiviral and immunologic effects of stavudine versus placebo in individuals with recent HIV infection; the st…
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CLINICAL_TRIALS trial_result · 2011-04-06Clinical Trial Update: Atazanavir Twice Daily [Phase 1]
This document reports the completion of a Phase 1 trial evaluating twice-daily atazanavir for HIV infections. The trial was sponsored by Bri…
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CLINICAL_TRIALS trial_result · 2011-03-14Clinical Trial Update: Studies of the Ocular Complications of AIDS (SOCA) CMV Retinitis Trial: Foscarnet-Ganciclovir Component [NA]
Clinical trial update for the SOCA study evaluating foscarnet-ganciclovir in CMV retinitis associated with AIDS; the study status is complet…
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CLINICAL_TRIALS trial_result · 2011-03-02Clinical Trial Update: Potent Antiviral Therapy for Critically Ill HIV Infected Patients Admitted to Intensive Care [Phase 3]
This document reports the completion of a Phase 3 clinical trial evaluating a potent antiviral therapy for critically ill HIV-infected patie…
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CLINICAL_TRIALS trial_result · 2011-03-01Clinical Trial Update: A Study of Nevirapine Used Alone or in Combination With AZT in HIV-1-Infected Children [NA]
This completed trial evaluated nevirapine used alone or in combination with AZT in HIV-1-infected children.
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CLINICAL_TRIALS trial_result · 2011-02-28Clinical Trial Update: Changing to Nonprotease Inhibitor Treatment to Improve Side Effects [Phase 2]
A Phase 2 clinical trial update examining switching to nonprotease inhibitor therapy to improve side effects in people with HIV infections a…
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CLINICAL_TRIALS trial_result · 2011-02-28Clinical Trial Update: Vitamin B Therapy for Hyperlactatemia [NA]
A completed clinical trial update examining Vitamin B therapy for hyperlactatemia in HIV infections. The update notes the study has finished…
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CLINICAL_TRIALS trial_result · 2011-02-04Clinical Trial Update: NNRTI vs PI Regimens for HIV Infected Women After They Have Taken Nevirapine to Prevent Mother-To-Child HIV Transmission [Phase 3]
Phase 3 trial comparing NNRTI versus protease inhibitor regimens for HIV-infected women after nevirapine exposure for prevention of mother-t…
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CLINICAL_TRIALS trial_result · 2011-01-04Clinical Trial Update: FOTO: Five Consecutive Days on Treatment With Efavirenz, Tenofovir, and Emtricitabine Followed by Two Days Off Treatment Versus Continuous Treatment [Phase 4]
Phase 4 trial comparing five consecutive days on ART (efavirenz, tenofovir, emtricitabine) followed by two days off versus continuous treatm…
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CLINICAL_TRIALS trial_result · 2010-10-26Clinical Trial Update: All About Youth: Evaluation of Sexual Risk Avoidance and Risk Reduction Programs for Middle School Students [NA]
A completed clinical trial evaluating sexual risk avoidance and risk reduction programs for middle school students, addressing sexually tran…
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CLINICAL_TRIALS trial_result · 2010-06-14Clinical Trial Update: A Study to Assess the Long-term Efficacy (24 Weeks) of MPC-4326 in Combination With a 2-3 Drug OBR Relative to the Efficacy of a 3-4 Drug ARV Regimen in Treatment Experienced HIV-1 Infected Subjects Who Are Failing Current Antiretroviral Therapy [Phase 2]
Phase 2 study evaluating the long-term efficacy of MPC-4326 in combination with an optimized background regimen versus a 3-4 drug antiretrov…
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CLINICAL_TRIALS trial_result · 2010-04-26Clinical Trial Update: TMC114-C227: A Study to Evaluate the Effectiveness and Safety of TMC114 (Darunavir) With a Low Dose of Ritonavir as Monotherapy (no Other Anti-HIV Drugs Will be Given) in Patients Who Have Never Been Treated With Antiretrovirals (Anti-HIV Drugs) Previously [Phase 2]
Phase 2 trial evaluating darunavir (TMC114) with low-dose ritonavir as monotherapy in antiretroviral-naive HIV patients was terminated.
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CLINICAL_TRIALS trial_result · 2010-03-11Clinical Trial Update: Culturally-Tailored HIV Risk Reduction for African-American MSM [NA]
A completed clinical trial evaluating culturally tailored HIV risk reduction for African-American men who have sex with men.
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CLINICAL_TRIALS trial_result · 2010-02-05Clinical Trial Update: Drug Interaction Study of Famotidine and Atazanavir With Ritonavir in HIV-Infected Patients [Phase 4]
A Phase 4 clinical trial evaluated drug interactions between famotidine and the HIV protease inhibitor atazanavir boosted with ritonavir in …
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CLINICAL_TRIALS trial_result · 2009-08-11Clinical Trial Update: Study of Pregabalin Versus Placebo in the Treatment of Nerve Pain Associated With HIV Neuropathy [Phase 3]
Phase 3 trial comparing pregabalin to placebo for nerve pain in HIV-associated neuropathy completed with results posted in 2009.
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CLINICAL_TRIALS research · 2009-05-15Clinical Trial Update: Cognitive and Psychosocial Benefits of MISC Training for Ugandan Children [NA]
Sponsor Makerere University reports on a clinical trial exploring cognitive and psychosocial benefits of MISC training for Ugandan children.…
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CLINICAL_TRIALS trial_result · 2009-03-23Clinical Trial Update: Open Label Safety And Efficacy Study Of Pregabalin In Subjects With Nerve Pain Asociated With Human Immunodeficiency Virus (HIV) Neuropathy [Phase 3]
Open-label safety and efficacy study of pregabalin for nerve pain in HIV-related peripheral neuropathy completed with results posted in 2009…
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CLINICAL_TRIALS trial_result · 2009-02-11Clinical Trial Update: VENICE Study Nevirapine Full Dose/Dose Escalation [Phase 4]
The VENICE Phase 4 trial evaluated full-dose versus dose-escalation nevirapine regimens in HIV-infected participants; the study is completed…
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CLINICAL_TRIALS trial_result · 2008-10-09Clinical Trial Update: Effect of an Online Video-Based Intervention to Increase HIV Testing in Men Who Have Sex With Men in Peru [NA]
This completed clinical trial evaluated an online video-based intervention to increase HIV testing among men who have sex with men in Peru.
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CLINICAL_TRIALS trial_result · 2008-09-17Clinical Trial Update: Treatment Intensification for HIV Infected Patients With Multi-Drug Resistant Virus [NA]
An update on an NIAID clinical trial evaluating intensified treatment for HIV infections with multi-drug resistant virus; no results or curr…
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CLINICAL_TRIALS trial_result · 2008-08-26Clinical Trial Update: A Phase I/II Trial of Ribavirin (With Escalation) + Isoprinosine in Asymptomatic HIV-Viremic Patients [Phase 1]
This entry describes a Phase I/II trial evaluating ribavirin (with escalation) plus isoprinosine in asymptomatic HIV-viremic patients. The s…
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: The Pharmacokinetics of Zidovudine and Oxazepam Alone and in Combination in the HIV-Infected Patient [Phase 1]
This Phase 1 pharmacokinetic study assesses Zidovudine and Oxazepam when given alone and in combination in HIV-infected patients.
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: The Safety and Effectiveness of BI-RG-587 in HIV-Infected Patients [Phase 1]
This Phase 1 trial assessed the safety and preliminary effectiveness of BI-RG-587 in HIV-infected patients and has completed the study.