HIV Infections
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CLINICAL_TRIALS trial_result · 2012-08-23Clinical Trial Update: Study Of An Investigational Regimen Including FDA Approved HIV Drugs In HIV-Infected Pediatric Subjects [Phase 2]
Phase 2 trial update of an investigational regimen including FDA-approved HIV drugs in HIV-infected pediatric subjects has completed with po…
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CLINICAL_TRIALS trial_result · 2012-08-17Clinical Trial Update: Investigating the Anti-Human Immunodeficiency Virus (HIV) & Anti-inflammatory Effect of Chloroquine [Phase 2, Phase 3]
A phase 2/3 clinical trial investigating chloroquine for HIV infections with anti-inflammatory effects was terminated; results were posted i…
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CLINICAL_TRIALS trial_result · 2012-08-14Clinical Trial Update: Retention and Duration of Activity of SPL7013 (VivaGel®) After Vaginal Dosing. [Phase 1, Phase 2]
Clinical trial update on retention and duration of activity of SPL7013 (VivaGel) after vaginal dosing, involving Phase 1 and Phase 2 studies…
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CLINICAL_TRIALS trial_result · 2012-07-26Clinical Trial Update: Bevacizumab to Treat Kaposi's Sarcoma in HIV-Positive and HIV-Negative Patients [Phase 2]
Phase 2 clinical trial evaluating bevacizumab for Kaposi's sarcoma in HIV-positive and HIV-negative individuals has completed with results p…
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CLINICAL_TRIALS trial_result · 2012-07-13Clinical Trial Update: Two Approaches to Routine HIV Testing in a Hospital Emergency Department [NA]
This trial compared two approaches to routine HIV testing in a hospital emergency department, with results posted after completion.
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CLINICAL_TRIALS trial_result · 2012-05-18Clinical Trial Update: A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS [NA]
A completed pilot clinical trial evaluated oral clindamycin with pyrimethamine for the treatment of toxoplasmic encephalitis in patients wit…
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CLINICAL_TRIALS trial_result · 2012-04-25Clinical Trial Update: Combination Pain Therapy in HIV Neuropathy [Phase 2]
Phase 2 trial update on combination pain therapy for HIV-associated peripheral neuropathy; study terminated with results posted in 2012.
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CLINICAL_TRIALS research · 2012-04-24Clinical Trial Update: Anti-HIV Drug Regimens and Treatment-Switching Guidelines in HIV Infected Children [Phase 2, Phase 3]
A study evaluating anti-HIV drug regimens and treatment-switching guidelines in HIV-infected children (Phase 2/Phase 3) has completed and po…
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CLINICAL_TRIALS trial_result · 2012-04-18Clinical Trial Update: HSV-2 Suppression to Reduce Maternal HIV-1 RNA Levels During Pregnancy and Breastfeeding [Phase 2]
Phase 2 trial evaluating HSV-2 suppression to reduce maternal HIV-1 RNA levels during pregnancy and breastfeeding.
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CLINICAL_TRIALS trial_result · 2012-04-12Clinical Trial Update: Toxicity Substudy of Evaluation of Subcutaneous Proleukin in a Randomised International Trial (ESPRIT): TOXIL-2 Substudy [Phase 3]
The ESPRIT TOXIL-2 toxicity substudy evaluating subcutaneous aldesleukin in HIV infections has been terminated.
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CLINICAL_TRIALS trial_result · 2012-03-22Clinical Trial Update: Safety and Efficacy of Switching From Stavudine or Zidovudine to Tenofovir DF in HIV-1 Infected Children [Phase 3]
Phase 3 trial evaluating safety and efficacy of switching HIV-1 infected children from stavudine or zidovudine to tenofovir disoproxil fumar…
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CLINICAL_TRIALS trial_result · 2012-02-24Clinical Trial Update: Adding Maraviroc to Antiretroviral Therapy for Suboptimal CD4 T-Cell Recovery Despite Sustained Virologic Suppression [NA]
Clinical trial investigating adding maraviroc to antiretroviral therapy for HIV patients with suboptimal CD4 T-cell recovery despite virolog…
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CLINICAL_TRIALS trial_result · 2012-02-09Clinical Trial Update: Safety of and Immune Response to an H1N1 Influenza Virus Vaccine in HIV Infected Children and Youth [Phase 2]
Phase 2 clinical trial evaluating safety and immune response of an H1N1 influenza vaccine in HIV-infected children and youth has completed w…
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CLINICAL_TRIALS trial_result · 2012-01-30Clinical Trial Update: Effectiveness of Palifermin in Increasing CD4 Counts in Treatment-Experienced HIV Infected Adults [Phase 2]
Phase 2 trial assessing palifermin for increasing CD4 counts in treatment-experienced HIV-infected adults has completed.
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CLINICAL_TRIALS trial_result · 2012-01-16Clinical Trial Update: Safety of and Immune Response to a Novel Human Papillomavirus Vaccine in HIV Infected Children [Phase 2]
Phase 2 trial update evaluating safety and immune response of a novel HPV vaccine in HIV-infected children.
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CLINICAL_TRIALS trial_result · 2011-11-07Clinical Trial Update: Safety and Efficacy Study of KP-1461 to Treat ART-Experienced HIV+ Patients [Phase 2]
A Phase 2 safety and efficacy study of KP-1461 in ART-experienced HIV patients has been terminated.
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CLINICAL_TRIALS trial_result · 2011-10-13Clinical Trial Update: Safety, Tolerability and Immune Response to LC002, an Experimental Therapeutic Vaccine, in Adults Receiving HAART [Phase 1, Phase 2]
Phase 1/2 trial investigating LC002, an experimental therapeutic vaccine, in adults on HAART for HIV infection; safety, tolerability, and im…
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CLINICAL_TRIALS trial_result · 2011-10-07Clinical Trial Update: Botswana Diarrheal Diseases Study
This is a completed clinical trial update from Harvard School of Public Health about the Botswana diarrheal diseases study, with HIV infecti…
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CLINICAL_TRIALS trial_result · 2011-10-04Clinical Trial Update: Effects of a Uridine Supplement on HIV Infected Adults With Lipoatrophy [Phase 2, Phase 3]
Phase 2/3 trial evaluating uridine supplementation in HIV-infected adults with lipoatrophy; results completed and posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-08-09Clinical Trial Update: HIV Treatment Reinitiation in Women Who Received Anti-HIV Drugs to Prevent Mother-to-Child Transmission of HIV [Phase 4]
Phase 4 trial evaluating HIV treatment reinitiation in women who previously received antiretroviral drugs to prevent mother-to-child transmi…
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CLINICAL_TRIALS trial_result · 2011-08-09Clinical Trial Update: Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings [Phase 4]
Phase 4 clinical trial evaluating antiretroviral combinations in treatment-naive HIV-infected individuals in resource-limited settings; comp…
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CLINICAL_TRIALS trial_result · 2011-06-23Clinical Trial Update: Effect of Addition of Raltegravir (MK-0518) to PI- or NNRTI-Based ART Regimens in HIV Infected Subjects With Undetectable Viral Load [Phase 2]
A Phase 2 trial evaluating the addition of raltegravir to protease inhibitor- or NNRTI-based ART in HIV-infected individuals with undetectab…
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EMA withdrawal · 2011-06-21EMA Withdrawn: Agenerase (amprenavir) — Glaxo Group Ltd.
Agenerase (amprenavir) has been withdrawn from the market in the EU.
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CLINICAL_TRIALS trial_result · 2011-06-13Clinical Trial Update: The Raltegravir and Ribavirin Pharmacokinetics (PK) Study [Phase 1]
Phase 1 PK study examining raltegravir and ribavirin in HIV infections; results posted after completion.
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CLINICAL_TRIALS trial_result · 2011-06-08Clinical Trial Update: Evaluating the Effect of CHanging EnfuvirtidE to Raltegravir in HIV Infected Subjects [Phase 3]
Phase 3 trial evaluating switching Enfuvirtide to Raltegravir in HIV-infected subjects; results completed and posted in 2011.