HIV Infection
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Sign up freeTop drugs studied for this disease
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FDA approval · 2020-08-21FDA Approved: STRIBILD — Supplemental Application (Gilead Sciences, Inc.)
The FDA approved a supplemental application for STRIBILD, a fixed-dose combination antiretroviral therapy.
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CLINICAL_TRIALS withdrawal · 2020-08-18Clinical Trial Update: Chloroquine Outpatient Treatment Evaluation for HIV-Covid-19 [Phase 3]
A Phase 3 clinical trial evaluating chloroquine for outpatient treatment of HIV and COVID-19 was withdrawn.
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CLINICAL_TRIALS trial_result · 2020-08-18Clinical Trial Update: Triple vs. Double Therapy in naïves HIV-Infected Patients [Phase 4]
A Phase 4 trial update comparing triple versus double therapy in treatment-naïve HIV-infected patients.
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CLINICAL_TRIALS trial_result · 2020-08-18Clinical Trial Update: Effects of a Protein Calorie Supplement in HIV-infected Women With Tuberculosis [NA]
A completed clinical trial evaluating the effects of a protein-calorie supplement in HIV-infected women with tuberculosis; results posted in…
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CLINICAL_TRIALS trial_result · 2020-08-11Clinical Trial Update: Pharmacokinetic Study of Pitavastatin and Ritonavir-Boosted Darunavir or Efavirenz [Phase 1]
Phase 1 pharmacokinetic study investigating interactions between pitavastatin and ritonavir-boosted darunavir or efavirenz in hyperlipidemia…
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CLINICAL_TRIALS trial_result · 2020-08-07Clinical Trial Update: A Clinical Trial to Evaluate the Efficacy and Safety of Elvitegravir / Cobicistat / Emtricitabine / Tenofovir Alafenamide as a First-line Treatment in Naïve Patients With HIV-1 Infection With Severe Immunosuppression [Phase 4]
Phase 4 trial evaluating a single-tablet regimen (elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide) as first-line therapy in trea…
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FDA approval · 2020-08-06FDA Approved: DOVATO — Supplemental Application (ViiV Healthcare Company)
FDA approved a supplemental application for DOVATO (dolutegravir sodium and lamivudine) submitted by ViiV Healthcare Company.
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CLINICAL_TRIALS research · 2020-08-06Clinical Trial Update: Safety Study of a Dual Anti-HIV Gene Transfer Construct to Treat HIV-1 Infection [Phase 1, Phase 2]
A dual anti-HIV gene transfer construct was studied in Phase 1/2 safety trials for HIV-1 infection; the study is completed with results post…
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CLINICAL_TRIALS trial_result · 2020-08-06Clinical Trial Update: Condom Performance in a Longitudinal Enhanced Assessment of User Experiences [NA]
Clinical trial update on condom performance from a longitudinal user experience study; results have been posted after completion.
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CLINICAL_TRIALS trial_result · 2020-08-04Clinical Trial Update: Latency and Early Neonatal Provision of Antiretroviral Drugs Clinical Trial [Phase 4]
Phase 4 clinical trial update on latency and early neonatal provision of antiretroviral drugs for HIV.
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: Continuation of Protease-Inhibitor Based Second-Line Therapy vs. Switch to B/F/TAF in Virologically Suppressed Adults [Phase 4]
A Phase 4 study comparing continuation of protease-inhibitor-based second-line therapy versus switching to B/F/TAF in virologically suppress…
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Nalmefene [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating naltrexone and nalmefene for HIV infection and alcohol use, with pain considerations; study completed …
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FDA label_change · 2020-07-31FDA Approved: PREZCOBIX — Supplemental Application (Janssen Products, LP)
FDA approved a supplemental application for PREZCOBIX (darunavir ethanolate and cobicistat) submitted by Janssen, resulting in a label updat…
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FDA approval · 2020-07-31FDA Approved: EVOTAZ — Supplemental Application (E.R. Squibb & Sons, L.L.C.)
The FDA approved a supplemental application for EVOTAZ (atazanavir and cobicistat) from E.R. Squibb & Sons, L.L.C. The action pertains to th…
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CLINICAL_TRIALS trial_result · 2020-07-31Clinical Trial Update: Virological Suppression in HIV Positive Patients Involved in a Novel Standardized Adherence Protocol [Phase 3]
A Phase 3 clinical trial reports virological suppression in HIV-positive patients under a novel standardized adherence protocol. The study i…
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EMA guidance · 2020-07-24Vaginal ring to reduce the risk of HIV infection for women in non-EU countries with high disease burden
EMA announces assessment of a vaginal ring for reducing HIV risk in women in non-EU countries with high disease burden, outlining potential …
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CLINICAL_TRIALS trial_result · 2020-07-23Clinical Trial Update: 3BNC117 Monoclonal Antibody in HIV-infected Subjects During Treatment Interruption [Phase 2]
Phase 2 trial updates on the monoclonal antibody 3BNC117 in HIV-1 infection during treatment interruption have completed with posted results…
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FDA approval · 2020-07-21FDA Approved: NEVIRAPINE — Supplemental Application (Micro Labs Limited)
FDA approved a supplemental application for NEVIRAPINE from Micro Labs Limited (ANDA 203080), authorizing a generic NEVIRAPINE product.
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CLINICAL_TRIALS trial_result · 2020-07-21Clinical Trial Update: Safety, Tolerability and Efficacy on Low Density Lipoprotein Cholesterol (LDL-C) of Evolocumab in Participants With Human Immunodeficiency Virus (HIV) and Hyperlipidemia/Mixed Dyslipidemia [Phase 3]
Phase 3 trial assessing safety, tolerability, and LDL-C reduction with evolocumab in HIV patients with hyperlipidemia/mixed dyslipidemia; co…
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: A Pharmacokinetic Study of Once Daily Efavirenz 400 mg Versus 600 mg in Thai HIV-1 Infected Subjects [Phase 2]
Phase 2 pharmacokinetic study comparing once-daily efavirenz 400 mg vs 600 mg in Thai HIV-1 infected subjects to evaluate PK differences.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: TDM of Generic Lopinavir/Ritonavir 200/50 mg [Phase 2]
Phase 2 clinical trial update on therapeutic drug monitoring (TDM) of generic lopinavir/ritonavir 200/50 mg for HIV treatment.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Pharmacokinetic Study of 2 Doses of ATV/r OD + 2 NRTIs in Thai HIV-1 Infected Patients [Phase 1, Phase 2]
Phase 1/2 pharmacokinetic study assessing two doses of ATV/r once daily plus two NRTIs in Thai HIV-1 infected patients; completed.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: The Immunogenicity of Varicella-zoster Virus Vaccine in HIV-infected Children [Phase 4]
Phase 4 trial assessing the immunogenicity of the varicella-zoster vaccine in HIV-infected children has been completed.
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Therapeutic Drug Monitoring (TDM) in Generic Tenofovir/Lamivudine/Efavirenz [Phase 2]
Phase 2 trial update on therapeutic drug monitoring for a generic three-drug regimen (tenofovir/emtricitabine/efavirenz) in HIV.
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CLINICAL_TRIALS research · 2020-07-17Clinical Trial Update: The Pharmacokinetics and Safety of IDV/r With NRTIs in HIV/TB Co-infected Patients Receiving Rifampicin [Phase 1, Phase 2]
Phase 1/2 trial updating pharmacokinetics and safety of IDV/r with NRTIs in HIV/TB co-infected patients on rifampicin.