HIV Infection
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: A Study to Evaluate the Antiviral Effect, Safety and Tolerability of GSK3810109A in Viremic Human Immunodeficiency Virus (HIV)-1 Infected Adults [Phase 2]
Phase 2 trial evaluating antiviral effect, safety and tolerability of GSK3810109A in viremic HIV-1 infected adults has completed with result…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults [Phase 2]
A Phase 2 dose-range finding trial in treatment-naive adults with HIV-1 has been terminated, and the study results have been posted.
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CLINICAL_TRIALS research · 2023-11-18Clinical Trial Update: Development of a Health-Related Symptom Index for Participants With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions
This clinical trial update describes the development of a health-related symptom index for participants with anal high-grade squamous intrae…
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CLINICAL_TRIALS research · 2023-11-15Clinical Trial Update: Implementing Oral (Event-driven and Daily) and Long-acting Pre-Exposure Prophylaxis in Mobile Men in Sub-Saharan Africa [Phase 3]
Phase 3 clinical trial evaluating oral (event-driven and daily) and long-acting pre-exposure prophylaxis in mobile men in Sub-Saharan Africa…
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CLINICAL_TRIALS trial_result · 2023-11-13Clinical Trial Update: Tambua Mapema Plus - to Discover HIV Infection Early and Prevent Onward Transmission [NA]
A completed clinical trial update for Tambua Mapema Plus aimed at early HIV infection detection and prevention of onward transmission; resul…
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CLINICAL_TRIALS trial_result · 2023-11-08Clinical Trial Update: A Digital Intervention for HIV Prevention in Black Adolescent Girls [NA]
Clinical trial completed evaluating a digital intervention for HIV prevention in Black adolescent girls; results posted.
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FDA approval · 2023-11-07FDA Approved: REYATAZ — Supplemental Application (E.R. Squibb & Sons, L.L.C.)
FDA approved a supplemental application for REYATAZ (atazanavir) submitted by E.R. Squibb & Sons, L.L.C. This action constitutes regulatory …
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FDA approval · 2023-11-07FDA Approved: REYATAZ — Supplemental Application (E.R. Squibb & Sons, L.L.C.)
FDA approved a supplemental application for Reyataz (atazanavir) filed by E.R. Squibb & Sons & L.L.C.
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Implementation Trial) [NA]
An implementation trial compared different delivery methods for the 3HP regimen (isoniazid–rifapentine) to prevent tuberculosis in individua…
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FDA approval · 2023-11-03FDA Approved: DOVATO — Supplemental Application (ViiV Healthcare Company)
The FDA approved a supplemental application for DOVATO (dolutegravir and lamivudine) from ViiV Healthcare Company.
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: Safety and Tolerability of AAV8 Delivery of a Broadly Neutralizing Antibody in Adults Living With HIV: a Phase 1, Dose-escalation Trial [Phase 1]
Phase 1 dose-escalation study assessing safety and tolerability of AAV8-delivered broadly neutralizing antibody in adults with HIV who have …
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: Efficacy of Doravirine + Dolutegravir Dual Therapy in the Context of Antiretroviral Therapy Switch [Phase 3]
Phase 3 trial evaluating Doravirine + Dolutegravir as a dual therapy for HIV-1 infection in switch regimens; recruitment ongoing.
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: Reducing Time to Spaced-out Appointments for Newly-diagnosed People Living With HIV [NA]
A completed clinical trial evaluating a strategy to reduce the time between spaced-out appointments for people newly diagnosed with HIV/AIDS…
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: Safer Conception for Women - Understanding Use of Periconception PrEP [Phase 4]
Phase 4 clinical trial update examining safer conception using periconception PrEP for women.
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: InTSHA: Interactive Transition Support for HIV-infected Adolescents Using Social Media [NA]
A completed clinical trial studying interactive transition support for HIV-infected adolescents using social media; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-10-19Clinical Trial Update: Raltegravir-based Antiretroviral Versus Maintaining Any Other Antiretroviral Therapy in HIV Mono-infected Patients [Phase 4]
Phase 4 trial comparing raltegravir-based antiretroviral therapy to maintaining any other ART in HIV mono-infected patients; completed study…
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CLINICAL_TRIALS trial_result · 2023-10-16Clinical Trial Update: Improving HIV Outcomes Among African American Transgender Women [NA]
A completed clinical trial focused on improving HIV outcomes among African American transgender women; results have been posted.
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: Poor Sleep and Inflammation in HIV-Infected Adults [NA]
A completed clinical trial studied poor sleep and inflammation in HIV-infected adults; results were posted in 2023.
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FDA approval · 2023-10-11FDA Approved: TRUVADA — Supplemental Application (Gilead Sciences, Inc)
The FDA approved a supplemental application for TRUVADA (emtricitabine and tenofovir disoproxil fumarate) from Gilead Sciences, finalizing a…
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FDA approval · 2023-10-05FDA Approved: LAMIVUDINE — Supplemental Application (Lupin Pharmaceuticals, Inc.)
FDA approved Lupin Pharmaceuticals' supplemental application for lamivudine, resulting in an approved generic lamivudine product. Lamivudine…
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CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV [NA]
Completed clinical trial evaluating Quit For Life (QFL) for smoking cessation among Chinese smokers living with HIV; results have been poste…
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CLINICAL_TRIALS trial_result · 2023-09-26Clinical Trial Update: Impact of a New Plant-based High-energy Oral Nutritional Supplement on Nutritional Outcomes in Malnourished Patients [Phase 4]
Phase 4 trial update assessing a new plant-based high-energy oral nutritional supplement for malnourished patients, with multiple listed con…
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CLINICAL_TRIALS trial_result · 2023-09-22Clinical Trial Update: The Shauriana Intervention for GBMSM in Kenya [NA]
This clinical trial update reports the completion of the Shauriana Intervention trial for HIV prevention among Kenyan GBMSM and notes that r…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Switch Strategy From Etravirine (ETR) to Doravirine (DOR) in Virologically-Suppressed HIV-1 Infected Adults With ETR-Resistance [Phase 4]
Phase 4 trial evaluating switching virologically suppressed HIV-1 adults with ETR resistance from etravirine to doravirine.
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: IN-US-276-1340: Pre-Exposure Prophylaxis to Prevent HIV Acquisition in US Women: A Demonstration Project [Phase 4]
Clinical trial update for a Phase 4 demonstration project assessing pre-exposure prophylaxis adherence monitoring to prevent HIV acquisition…