HIV Infection
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CLINICAL_TRIALS research · 2024-02-26Clinical Trial Update: Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia [Phase 4]
A Phase 4 clinical trial assessing intervention strategies related to HIV, drug use, and the criminal justice system in Malaysia has complet…
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FDA approval · 2024-02-23FDA Approved: BIKTARVY — Supplemental Application (Gilead Sciences, Inc.)
The FDA approved a supplemental application for BIKTARVY (bictegravir, emtricitabine, and tenofovir alafenamide fumarate) submitted by Gilea…
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CLINICAL_TRIALS trial_result · 2024-02-23Clinical Trial Update: Impact of Long-acting Injectable Cabotegravir for HIV PrEP in MSM in France. [Phase 3]
Phase 3 trial update on long-acting injectable cabotegravir for HIV PrEP in men who have sex with men in France; status not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-02-21Clinical Trial Update: Efficacy of Dolutegravir Plus Lamivudine in HIV-1-infected Treatment-naïve Adults Without a Baseline Genotyping Test [Phase 4]
Phase 4 trial update evaluating efficacy of dolutegravir plus lamivudine in treatment-naïve HIV-1–infected adults without baseline genotypin…
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CLINICAL_TRIALS trial_result · 2024-02-21Clinical Trial Update: Call for Life Youth ART Adherence Study [NA]
Clinical trial update for an ART adherence study among youth; study completed with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-02-20Clinical Trial Update: TechStep: Technology-based Stepped Care to Stem Transgender Adolescent Risk Transmission [NA]
A completed clinical trial (TechStep) evaluating a technology-based stepped care approach for reducing HIV risk transmission in transgender …
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CLINICAL_TRIALS trial_result · 2024-02-14Clinical Trial Update: Interrupting HIV and TB Stigma in the Household in Uganda [NA]
A completed clinical trial in Uganda explored interventions to interrupt HIV and tuberculosis stigma within households, with results posted …
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FDA approval · 2024-02-13FDA Approved: RUKOBIA — Supplemental Application (ViiV Healthcare Company)
FDA approves a supplemental application for RUKOBIA (fostemsavir tromethamine) from ViiV Healthcare Company.
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CLINICAL_TRIALS trial_result · 2024-02-13Clinical Trial Update: PD-1 Inhibition to Determine CNS Reservoir of HIV-Infection [Phase 1]
Phase 1 trial evaluating PD-1 inhibition to determine the central nervous system reservoir of HIV infection; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-02-13Clinical Trial Update: A Study of a Nucleoside Sparing Regimen in HIV-1 Infected Patients With Detectable Viremia [Phase 2]
Phase 2 clinical trial update for a nucleoside-sparing regimen in HIV-1 infected patients with detectable viremia.
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CLINICAL_TRIALS trial_result · 2024-02-09Clinical Trial Update: Switch From Dual Regimens Based on Dolutegravir Plus a Reverse Transcriptase Inhibitor to E/C/F/TAF in Virologically Suppressed, HIV-1 Infected Patients (Be-OnE) [Phase 3]
Phase 3 trial Be-OnE evaluating switching virologically suppressed HIV-1 patients from dolutegravir-based regimens to E/C/F/TAF; study termi…
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CLINICAL_TRIALS trial_result · 2024-02-08Clinical Trial Update: Addressing Drug Use Stigma in Human Immunodeficiency Virus (HIV) Care and Treatment Clinics in Tanzania [NA]
A completed clinical trial in Tanzania evaluated approaches to reduce drug use stigma in HIV treatment clinics, with results publicly posted…
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FDA approval · 2024-02-06FDA Approved: EFAVIRENZ — Supplemental Application (Cipla USA Inc.)
The FDA approved a supplemental application for Efavirenz (generic) from Cipla USA Inc. under ANDA 204766.
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CLINICAL_TRIALS trial_result · 2024-02-05Clinical Trial Update: Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women [NA]
A completed clinical trial comparing two intrauterine devices (IUDs) conducted among HIV-positive women in Cape Town; results posted in 2024…
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CLINICAL_TRIALS trial_result · 2024-02-05Clinical Trial Update: Optimizing Reversal of HIV Latency With Combination Therapy [Phase 1, Phase 2]
Early-phase clinical trial update exploring combination therapy to optimize reversal of HIV latency.
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB [Phase 4]
Phase 4 trial update evaluating the pharmacokinetics of twice-daily or once-daily DTG (50 mg) in children with HIV and tuberculosis.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Task-shifted Adaptation of the WHO-PEN Intervention to Address Cardio-metabolic Complications in People Living With HIV in Zambia [NA]
A completed clinical trial evaluating task-shifted adaptations of the WHO-PEN intervention to address cardio-metabolic complications in peop…
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CLINICAL_TRIALS trial_result · 2024-01-25Clinical Trial Update: Study of Interferon-Gamma in the Complex Treatment of Patients Infected With HIV and Tuberculosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating interferon-gamma as part of complex treatment for patients with HIV and tuberculosis has completed, wi…
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CLINICAL_TRIALS trial_result · 2024-01-18Clinical Trial Update: Agricultural Intervention for Food Security and HIV Health Outcomes in Kenya [NA]
Clinical trial update from Kenya evaluating an agricultural intervention to improve food security and HIV health outcomes; the study is comp…
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Developing Online Interventions to Reduce Stigma-Related Stress, Sexual Health, and HIV Risk Among Young Chinese MSM [NA]
Clinical trial completed that developed online interventions aimed at reducing stigma-related stress, sexual health issues, and HIV risk amo…
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Pharmacokinetics and Safety of SAR441236 [Phase 1]
Phase 1 pharmacokinetics and safety update for SAR441236 in HIV-1 infection; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: Allogeneic Adoptive Immune Therapy for Advanced AIDS Patients [Phase 2]
Phase 2 clinical trial update for allogeneic adoptive immune therapy in advanced AIDS patients.
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CLINICAL_TRIALS trial_result · 2023-12-28Clinical Trial Update: Single-cell CBD Biomarkers of Inflammation Reduction in People Living With HIV [Phase 4]
Phase 4 trial investigating single-cell CBD biomarkers of inflammation reduction in people living with HIV has been completed with results p…
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CLINICAL_TRIALS trial_result · 2023-12-28Clinical Trial Update: Mhealth for PrEP Adherence by Young Adult MSM, Phase 2 [NA]
Phase 2 clinical trial update on mobile health support for PrEP adherence in young adult men who have sex with men; study completed with res…
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CLINICAL_TRIALS trial_result · 2023-12-21Clinical Trial Update: Switching From TDF-based Antiretroviral Therapy Regimens to B/F/TAF in Virally Suppressed Adults With HIV-1 Infection [Phase 4]
Phase 4 trial update evaluating switching from TDF-based ART regimens to B/F/TAF in virally suppressed adults with HIV-1 infection.