HIV Infection
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Integrated Online-to-offline (O2O) Model of Care for HIV Prevention and Treatment Among Transgender Women (CINTAI) [NA]
A clinical trial evaluating an integrated online-to-offline model of care for HIV prevention and treatment among transgender women, currentl…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: An Adaptive Intervention for Depression Among Latinos Living With HIV [NA]
A completed clinical trial evaluating an adaptive intervention for depression among Latinos living with HIV, with results posted on 2024-10-…
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FDA approval · 2024-10-18FDA Approved: ATAZANAVIR SULFATE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for Atazanavir Sulfate (Teva Pharmaceuticals USA, Inc.). This reflects a regulatory update to the dr…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Efficacy of Serious Game Interventions on HCV Education for HIV Patients [NA]
A clinical trial is evaluating whether serious game interventions improve education about Hepatitis C among people living with HIV.
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: Efficacy of Switching to DTG/3TC in Virologically-suppressed Adults Currently on B/F/TAF [Phase 4]
Phase 4 trial assessing switching virologically suppressed adults from bictegravir/emtricitabine/tenofovir alafenamide to dolutegravir/lamiv…
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EMA approval · 2024-10-16EMA Authorised: Reyataz (atazanavir (as sulfate)) — Bristol-Myers Squibb Pharma EEIG
The EMA authorised Reyataz (atazanavir sulfate) for HIV infections; the marketing authorization holder is Bristol-Myers Squibb Pharma EEIG.
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Clinical Trial of HIV Vaccine Combinations in Healthy Men and Women [Phase 1]
Phase 1 trial evaluating HIV vaccine combinations in healthy men and women has completed, with results posted. The study assessed safety and…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Dolutegravir/Rilpivirine, Antiretroviral Efficacy Study Using Real-world Data in Subjects With Human Immunodeficiency Virus (HIV)-1
Clinical trial update reporting results from a real-world data study evaluating the antiretroviral efficacy of the Dolutegravir/Rilpivirine …
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults [Phase 3]
A Phase 3 trial evaluating pitavastatin for reducing cardiovascular risk in HIV-infected adults has completed, with results posted in Octobe…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: An Italian Observation of Antiretroviral Treatment in Participants Taking Darunavir/ Cobicistat Plus Emtricitabine and Tenofovir Alafenamide Fumarate
An Italian observational study evaluated outcomes for people with HIV treated with Symtuza (darunavir/cobicistat/emtricitabine/tenofovir ala…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Antiretroviral Regimens Containing Raltegravir for Prophylaxis of Mother-to-child-transmission of HIV Infection [Phase 2, Phase 3]
Phase 2/3 trial evaluating regimens containing raltegravir to prevent mother-to-child transmission of HIV was terminated, with results poste…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Humoral and Cellular Immunity Against SARS-COV-2 Vaccine in HIV-infected Patients Immunosuppressed
This clinical trial update reports on humoral and cellular immune responses to a SARS-CoV-2 vaccine in HIV-infected, immunosuppressed indivi…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Establishment of a Database of HIV Subjects Initiating or Simplifying Dual Therapy With Dolutegravir/Lamivudine
This clinical trial update describes the creation of a database to study HIV infection patients initiating or simplifying dual therapy with …
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CLINICAL_TRIALS research · 2024-10-10Clinical Trial Update: The Expand Study-Pharmacist Administered Long Acting Cabotegravir + Rilpivirine to Expand Access for People With HIV
This clinical trial update describes the Expand Study, which aims to expand access to pharmacist-administered long-acting cabotegravir plus …
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Traditional Healer-initiated HIV Counseling and Testing in South Africa [NA]
A completed clinical trial in South Africa evaluating traditional healer-initiated HIV counseling and testing, with results posted on 2024-1…
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FDA approval · 2024-10-08FDA Approved: BIKTARVY — Supplemental Application (Gilead Sciences, Inc.)
The FDA approved a supplemental application for BIKTARVY, the fixed-dose combination HIV-1 therapy from Gilead Sciences.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Incidence of Metabolic Syndrome in People Living With HIV Without ExperienCe to ART Who Start DoLutegravir Based-Regimen Compared With BictegrAvir Based-RegimeN [NA]
This completed clinical trial compared the incidence of metabolic syndrome in people living with HIV who start on a dolutegravir-based regim…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: "Observational Study on Tolerability and Observance of Post-exposure Prophylaxis With Doravirine in HIV Viral Risk"
This completed observational study assessed tolerability and adherence of doravirine used as post-exposure prophylaxis in individuals at ris…
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: PrEPsmart 2-1-1 Pilot [Phase 2]
Phase 2 clinical trial update for PrEPsmart 2-1-1 Pilot in HIV infection; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Caregiver Peer Support and ART Adherence Among Children [NA]
A clinical trial on caregiver peer support and adherence to antiretroviral therapy among children with HIV has completed.
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CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: Clinical Trial to Evaluate the Effects of Letermovir Prophylaxis on T-cell Immune Activation in Participants With Treated HIV-1 Infection [Phase 2]
This Phase 2 trial evaluates whether letermovir prophylaxis affects T-cell immune activation in participants with treated HIV-1 infection; t…
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: Risk-factors for Multidrug-resistant Bacteria Colonization Among Patients at High Risk of STIs
Completed clinical trial evaluating risk factors for colonization with multidrug-resistant bacteria among people at high risk of sexually tr…
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: Long-acting Biomedical HIV Prevention in Transgender Women [NA]
The clinical trial evaluating long-acting biomedical HIV prevention in transgender women has been terminated.
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CLINICAL_TRIALS trial_result · 2024-10-03Clinical Trial Update: Pharmacologic Strategies to Use the Levonorgestrel Implant in HIV-infected Women [Phase 2]
Phase 2 clinical trial evaluating pharmacologic strategies for using the levonorgestrel implant in HIV-infected women.
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CLINICAL_TRIALS research · 2024-10-03Clinical Trial Update: A Promotion and Implementation Project of HIV Pre-Exposure Prophylaxis Among High Risk Population [NA]
A completed implementation study promoting HIV pre-exposure prophylaxis among high-risk populations.