HIV Infection
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Integrated Mental Health Care for Pregnant Women With HIV in Kenya: The Tunawiri Study [NA]
This clinical trial in Kenya, sponsored by University of Colorado, Denver, aims to evaluate integrated mental health care for pregnant women…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Economic Navigation and Strengthening to Research Unrestricted Services for Transgender Women (ENTRUST) [NA]
Clinical trial update for ENTRUST, a University of Central Florida study on economic navigation and strengthened unrestricted services for t…
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FDA approval · 2024-12-05FDA Approved: REYATAZ — Supplemental Application (E.R. Squibb & Sons, L.L.C.)
The FDA approved a supplemental application for Reyataz (atazanavir) from E.R. Squibb & Sons, L.L.C., updating the labeling as part of an ap…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Strengthening Evidence on Optimal Multidrug-resistant Tuberculosis Treatment Regimens
Clinical trial update highlighting efforts to strengthen evidence for optimal multidrug-resistant tuberculosis regimens, including considera…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Instacare - Rapid ART Initiation Among Persons With HIV and Out of Care
The Instacare study reports results from rapid ART initiation among people with HIV who are out of care; the trial status is completed.
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: A Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein BG505 SOSIP.GT1.1 Gp140 Vaccine, Adjuvanted in Healthy, HIV-uninfected Adults [Phase 1]
This Phase 1 trial update reports completion of a study evaluating the safety and immunogenicity of the recombinant HIV-1 BG505 SOSIP.GT1.1 …
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Comparing Immune Activation and Latent HIV Reservoir Size Between People Living With HIV on Tenofovir-containing Versus NRTI-free ART
Clinical Trial Update comparing immune activation and latent HIV reservoir size between people on tenofovir-containing ART versus NRTI-free …
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Variation in Drug Interactions in People With HIV (PLWH) Aged 60 Years and Older.
This clinical trial update describes a study on variation in drug interactions in people with HIV aged 60 years and older, which is currentl…
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FDA approval · 2024-12-04FDA Approved: EMTRICITABINE AND TENOFOVIR DISOPROXIL FUMARATE — Supplemental Application (Zydus Pharmaceuticals USA Inc.)
FDA approves a supplemental application for Emtricitabine and Tenofovir Disoproxil Fumarate by Zydus Pharmaceuticals USA Inc., confirming re…
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CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: B-free Multistage Trial [Phase 4]
An ongoing Phase 4 trial called 'B-free Multistage Trial' is enrolling by invitation for HIV infection with drug resistance; no specific dru…
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels [Phase 1]
Phase 1 drug-drug interaction study of Vesatolimod in adults with HIV infection was terminated and results have been posted.
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Pertussis Immunization During Pregnancy & HIV Infection
Clinical trial update on pertussis vaccination during pregnancy in women with HIV infection; the study is completed.
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CLINICAL_TRIALS trial_result · 2024-12-02Clinical Trial Update: Study of EBT-101 in Aviremic HIV-1 Infected Adults on Stable ART [Phase 1]
Excision BioTherapeutics reports the completion of a Phase 1 trial evaluating EBT-101 in aviremic HIV-1-infected adults on stable antiretrov…
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: APPROACH 2.0: HIV, HCV and Syphilis Testing Through Pharmacies [NA]
A clinical trial update about the APPROACH 2.0 study on HIV, HCV, and syphilis testing through pharmacies; the trial is currently active but…
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CLINICAL_TRIALS research · 2024-11-29Clinical Trial Update: Filling Gaps in the HIV Pre-exposure Prophylaxis Cascade Through Counseling [NA]
An upcoming Unity Health Toronto study aims to fill gaps in the HIV PrEP cascade with counseling, and it is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-11-27Clinical Trial Update: Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of HIV-1 Chimp Adenovirus Vaccines Expressing Clade C gp140 & CH505TF gp120 Protein Boost in HIV-uninfected Adult. [Phase 1]
A Phase 1 study assessing the safety and immunogenicity of HIV-1 chimpanzee adenovirus vaccines expressing clade C gp140 with a CH505TF gp12…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Establish and Characterize an Acute HIV Infection Cohort in a High Risk Population
This clinical trial update describes efforts to establish and characterize a cohort of individuals with acute HIV infection in a high-risk p…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Characteristics of Immunity in Gut Mucosa, Spinal Fluid, Lymph Node and Blood of HIV Negative Thais and Thais with HIV Infection [NA]
Clinical trial update describing the immune characteristics in gut mucosa, spinal fluid, lymph nodes, and blood among HIV-negative and HIV-i…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: A Global Registry On Second gEneration and Long-acting inTegrase inhibiTor fAilures
This document provides an update on a global registry tracking failures of second-generation and long-acting integrase inhibitors in HIV the…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Study to Assess the Effects of Cabotegravir (CAB) and Rilpivirine (RPV) Long-Acting (LA) Injections Following Sub-cutaneous (SC) Administration Compared With Intramuscular (IM) Administration in Adult Participants Living With Human Immunodeficiency Virus (HIV-1) Infection in the FLAIR Study [Phase 3]
Phase 3 FLAIR study comparing subcutaneous versus intramuscular injections of long-acting cabotegravir and rilpivirine in adults with HIV-1 …
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Improving Health Outcomes in Young Cisgender Men and Transgender Women (mLab App) [NA]
Clinical trial update for the mLab App focusing on improving health outcomes in young cisgender men and transgender women with HIV infection…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: HIV Self-Testing AND Uptake and Retention of PrEP Among Older Adolescent MSM and TGW
Update on a completed clinical trial evaluating HIV self-testing and uptake/retention of PrEP among older adolescent men who have sex with m…
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FDA approval · 2024-11-25FDA Approved: SUNLENCA — Supplemental Application (Gilead Sciences, Inc.)
The FDA approved a supplemental application for Sunlenca (lenacapavir sodium) from Gilead Sciences. This action approves a supplemental NDA …
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FDA approval · 2024-11-25FDA Approved: SUNLENCA — Supplemental Application (Gilead Sciences, Inc.)
The FDA approved a supplemental application for Sunlenca (lenacapavir sodium) submitted by Gilead Sciences, Inc. The action pertains to the …
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Differentiated Service Delivery for Antiretroviral Therapy
This clinical trial evaluated differentiated service delivery models for antiretroviral therapy in HIV infection. The study status is comple…