HIV Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Goals for Adherence with Low-cost Incentives [NA]
RAND reports a clinical trial focused on improving adherence to antiretroviral therapy for people with HIV using low-cost incentives; the st…
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Feasibility of HIV Prevention Cohort Studies Among Men Who Have Sex With Men in Sub-Saharan Africa
This completed feasibility study reports on HIV prevention cohort research among men who have sex with men in Sub-Saharan Africa, sponsored …
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: HIV Self Testing of Male Partners of Women in PMTCT [NA]
The study on HIV self-testing among male partners of women in PMTCT programs has completed, with results posted on 2025-03-27.
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP [Phase 4]
Phase 4 clinical trial from the University of Connecticut investigating optimized HIV prevention for people who inject drugs on PrEP; curren…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women [Phase 1]
A Phase 1 study evaluating potential drug interactions between doravirine and estradiol or spironolactone in healthy transgender women; resu…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: MK-8527 Single-Dose Trial in HIV-1 Infected Participants (MK-8527-004) [Phase 1]
Merck completed a single-dose Phase 1 trial (MK-8527-004) in HIV-1 infected participants; results have been posted.
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CLINICAL_TRIALS withdrawal · 2025-03-26Clinical Trial Update: A Clinical Trial in Adult Participants Without HIV and in Overall Good Health to Evaluate the Safety and Immunogenicity of CD4BS CH505M5 Pr-NP1 Followed by CH505 TF chTrimer Boost Both Adjuvanted With Either Lipid Nanoparticles (LNPs) or 3M-052-AF + Alum [Phase 1]
A Phase 1 HIV vaccine trial evaluating CH505M5 Pr-NP1 followed by CH505 TF chTrimer boost with LNPs or 3M-052-AF + Alum was withdrawn.
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Effects of Cash Transfer for the Prevention of HIV in Young South African Women [Phase 3]
Phase 3 trial update on cash transfers to prevent HIV in young South African women; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Safety, Tolerability, and Efficacy of IL-15 Superagonist (N-803) With and Without Combination Broadly Neutralizing Antibodies to Induce HIV-1 Control During Analytic Treatment Interruption [Phase 1]
A Phase 1 study evaluating the safety, tolerability, and preliminary efficacy of the IL-15 superagonist N-803, with and without broadly neut…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Dose-Proportionality and Intra-Individual Variability of Intracellular TFV-DP and FTC-TP in Healthy Volunteers [Phase 1]
Phase 1 study in healthy volunteers evaluating dose proportionality and intra-individual variability of intracellular TFV-DP and FTC-TP afte…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Clinical Opportunities and Management to Exploit Biktarvy as Asynchronous Connection Key (COMEBACK) [NA]
A completed clinical trial update examining opportunities and management strategies for using Biktarvy in HIV infection.
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Enhanced Problem-solving Therapy and HIV Engagement Support to Improve Perinatal Mental Health & HIV Outcomes in Malawi [NA]
A recruiting clinical trial in Malawi is evaluating enhanced problem-solving therapy plus HIV engagement support to improve perinatal mental…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Ayaangwaamiziwin Initiative: Carefulness and Preparedness [NA]
Trial update for the Ayaangwaamiziwin Initiative focusing on point-of-care testing for HIV and syphilis; the study is currently active but n…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Enhancing Recruitment, Linkage to Care and Treatment for HIV-Infected MSM in the United States [NA]
This clinical trial update notes the completion of a study focused on improving recruitment, linkage to care, and treatment for HIV-infected…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: A Comparison of Different Community Models of ART Delivery Amongst Stable HIV+ Patients in Two Urban Settings in Zambia [NA]
This completed clinical trial compared different community models for delivering antiretroviral therapy to stable HIV-positive patients in t…
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FDA approval · 2025-03-21FDA Approved: PREZCOBIX — Supplemental Application (Janssen Products, LP)
The FDA approved a supplemental application for PREZCOBIX (darunavir ethanolate and cobicistat) from Janssen Products, LP, expanding its lab…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIV [Phase 1, Phase 2]
The trial update summarizes pharmacokinetics, safety, and tolerability findings for bedaquiline in infants, children, and adolescents with m…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Feasibility of HIIT in Older Adults with HIV and Hypertension [NA]
The clinical trial update reports the completion of a feasibility study evaluating high-intensity interval training (HIIT) in older adults w…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: A Clinical Trial to Evaluate Safety, Tolerability, and Immunogenicity of Adjuvanted HIV-1 Fusion Peptide Conjugate Vaccine Alone or in Prime-Boost Regimens With Adjuvanted HIV-1 Envelope Trimer 4571 and HIV-1 Trimer 6931 Vaccines in Healthy Adults [Phase 1]
A Phase 1 clinical trial evaluated safety, tolerability, and immunogenicity of an adjuvanted HIV-1 Fusion Peptide Conjugate Vaccine given al…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Assessing Perceptions and Preferences Around Long-acting Injectables (APPLI) [NA]
A completed clinical trial evaluating perceptions and preferences around long-acting injectable therapies for HIV.
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: HIV/STI Risk Reduction for Incarcerated Women With Interpersonal Violence [NA]
A completed clinical trial evaluating HIV/STI risk-reduction interventions for incarcerated women who experience interpersonal violence.
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV
A clinical trial investigating virologic and immunologic characteristics of severe monkeypox in people with advanced HIV.
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Viral Infection of HSPC Impacts Hematopoiesis
A clinical trial investigating how viral infections of hematopoietic stem and progenitor cells impact hematopoiesis is currently recruiting,…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: HIV Clinic-Based Intervention to Improve ART Adherence and Prevent HIV Transmission [NA]
A completed CDC-sponsored clinical trial assessed a clinic-based intervention to improve adherence to antiretroviral therapy and reduce HIV …
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EMA approval · 2025-03-19EMA Authorised: Tenofovir disoproxil Zentiva (tenofovir disoproxil phosphate) — Zentiva k.s.
The European Medicines Agency authorised Tenofovir disoproxil Zentiva for HIV infections; the active substance is tenofovir disoproxil phosp…