HIV Infection
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Optimization of Cervical Cancer Screening Strategies Among Women Living With HIV: Effectiveness and Implementation of Decentralized Approach Using a Mobile Team With HPV Testing in the Western Region of Cameroon [NA]
A study evaluating a decentralized cervical cancer screening approach using mobile teams and HPV testing for women living with HIV in Camero…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: A Study to Evaluate Efficacy, Safety and Tolerability in Antiretroviral Therapy (ART)-Experienced Participants of at Least 50 Years of Age Living With Human Immunodeficiency Virus (HIV) With Virologic Suppression Who Switch to DTG/3TC FDC From BIC/FTC/TAF [Phase 3]
A Phase 3 trial evaluating efficacy, safety, and tolerability in ART-experienced adults aged 50 or older with virologic suppression who swit…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Using CBPR to Engage Hazardous Drinking Women in the HIV Prevention and Care Continuum [NA]
Johns Hopkins University is conducting a CBPR-based clinical trial to engage hazardous-drinking women in HIV prevention and care; the study …
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV [Phase 4]
This Phase 4 clinical trial update from Yale University reports results of a new approach to treating tobacco use disorder in people living …
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV [Phase 2]
Phase 2 clinical trial investigating tirzepatide for weight loss and chronic inflammation in people with HIV; currently recruiting.
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FDA approval · 2025-11-26FDA Approved: CABENUVA — Supplemental Application (ViiV Healthcare Company)
The FDA approved a supplemental application for CABENUVA (cabotegravir and rilpivirine) from ViiV Healthcare Company. This action updates th…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of Concern [Phase 2, Phase 3]
This report summarizes efficacy results from a Phase 2/3 study of a COVID-19 mRNA vaccine in regions with SARS-CoV-2 variants of concern. Re…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Gene Therapy After Frontline Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin Lymphoma [Phase 1]
A Phase 1 clinical trial is evaluating a gene therapy following frontline chemotherapy in patients with AIDS-related non-Hodgkin lymphoma an…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: HIV-1 Subtype-specific Drug Resistance in Patients Failing Dolutegravir (DTG) Based Regimen
A completed clinical trial update examining HIV-1 subtype-specific drug resistance in patients failing a dolutegravir-based regimen.
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Impact of a Telenovela/Soap Opera for HIV Prevention in Latinas [NA]
The University of North Carolina completed a clinical trial evaluating a telenovela/soap opera intervention designed to prevent HIV among La…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Couples Health CoOp Plus [NA]
Clinical trial update indicates the RTI International-sponsored couples health study (HIV and substance use, including stigma/social factors…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM - Aim 3 [NA]
This update summarizes the completed results of an online mindfulness-based intervention designed to reduce minority stress and HIV risk amo…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Integrating Project YES! With WHO-Endorsed Mental Health Approaches Among Youth Living With HIV [NA]
A Johns Hopkins-led clinical trial aims to integrate Project YES! with WHO-endorsed mental health approaches for youth living with HIV and i…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Text Messaging to Promote HIV Testing in Gay Men [NA]
This update reports the completion of a clinical trial evaluating whether text messaging can promote HIV testing among gay men. The study wa…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Pre-exposure Prophylaxis (PrEP) Adherence for Black MSM [NA]
A clinical trial update for a PrEP adherence study targeting Black men who have sex with men; the study is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Antiretroviral Therapy (ART) (MK-8591A-051) [Phase 3]
Phase 3 trial evaluating switching virologically suppressed HIV-1 patients from currently approved ART to a doravirine/islatravir regimen (M…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Community Solutions to Adolescent Research Consent - Minor Consent for Biomedical HIV Research
This clinical trial update reports on the completion of a study examining minor consent for biomedical HIV research in adolescents.
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Managing Hypertension Among People Living With HIV [NA]
ClinicalTrials.gov entry notes a completed study on managing hypertension among people living with HIV. No results are described in the prov…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: A Study Evaluating the Safety of Cal-1 (LVsh5/C46) Drug Product in HIV-1 Infected Patient With High Risk Lymphoma [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating the safety of Cal-1 (LVsh5/C46) in an HIV-1-infected patient with high-risk lymphoma.
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: HIV Patients Cohort [NA]
Clinical trial update for an HIV patient cohort (NCT02203006) showing the study is active but not recruiting, sponsored by Assistance Publiq…
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EMA approval · 2025-11-19EMA Authorised: Descovy (emtricitabine;tenofovir alafenamide) — Gilead Sciences Ireland UC
EMA authorised Descovy (emtricitabine and tenofovir alafenamide) for HIV infections; MAH: Gilead Sciences Ireland UC.
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM [NA]
A completed clinical trial evaluated an online mindfulness-based intervention to reduce minority stress and HIV risk among young adult men w…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Pilot Testing Into the Feasibility of the Developed Cognitive Behavioral Therapy Intervention [NA]
This clinical trial update describes the feasibility pilot of a developed cognitive behavioral therapy intervention for participants with HI…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Reducing Systemic Inflammation in People on Antiretroviral Therapy [Phase 2]
A Phase 2 clinical trial is currently recruiting to test strategies for reducing systemic inflammation in people living with HIV on antiretr…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) (MK-8591A-052) [Phase 3]
Phase 3 trial MK-8591A-052 evaluates switching virologically suppressed HIV-1 patients from bictegravir/emtricitabine/tenofovir alafenamide …