HIV Infection
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CLINICAL_TRIALS research · 2008-03-04Clinical Trial Update: Intermittent Versus Continuous Medication in the Treatment of HIV [Phase 4]
This update reports on a Phase 4 trial comparing intermittent versus continuous HIV medication regimens; the study has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Interventions to Decrease the Risk of Mother-to-Child Transmission of HIV in India
A clinical trial investigating interventions to reduce mother-to-child transmission of HIV in India has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Effects of HIV on the Development and Function of Bone Marrow Cells
A completed clinical trial investigated how HIV affects the development and function of bone marrow cells.
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CLINICAL_TRIALS research · 2008-03-04Clinical Trial Update: Evaluation and Natural History of Children With Cancer and AIDS
A National Cancer Institute study update describing the evaluation and natural history of cancer in children with AIDS/HIV infection; the st…
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CLINICAL_TRIALS trial_result · 2008-02-29Clinical Trial Update: Study on the Effect of Kaletra + Nevirapine as Maintenance Bitherapy Compared to a Triple Therapy Including Kaletra + Analogues in HIV Patients [Phase 4]
A Phase 4 clinical trial comparing Kaletra (lopinavir/ritonavir) plus Nevirapine maintenance therapy versus a Kaletra-containing triple ther…
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FDA approval · 2008-02-25FDA Approved: PREZISTA — Supplemental Application (Janssen Products LP)
The FDA approved a supplemental application for Prezista (darunavir) submitted by Janssen Products LP.
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FDA label_change · 2008-02-20FDA Approved: REYATAZ — Supplemental Application (E.R. Squibb & Sons, L.L.C.)
The FDA approved a supplemental application for Reyataz (atazanavir) submitted by E.R. Squibb & Sons, L.L.C., resulting in changes to the dr…
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FDA approval · 2008-02-13FDA Approved: VIRACEPT — Supplemental Application (AGOURON)
FDA approved a supplemental application for Viracept (nelfinavir mesylate) submitted by Agouron.
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FDA approval · 2008-02-13FDA Approved: VIRACEPT — Supplemental Application (AGOURON)
FDA approved a supplemental application for VIRACEPT (nelfinavir mesylate) submitted by Agouron.
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CLINICAL_TRIALS trial_result · 2008-02-12Clinical Trial Update: Efficacy and Safety to Extend Treatment 24 Weeks in co-Infected HIV-HCV Genotype 1 and/or 4 [Phase 4]
Phase 4 trial evaluating extending treatment to 24 weeks in HIV-Hepatitis C co-infected patients (genotypes 1 and/or 4), with outcomes on ef…
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CLINICAL_TRIALS research · 2008-02-11Clinical Trial Update: Two Different Treatments 24 vs 48 Weeks Chronic Hepatitis C Genotypes 2 and/or 3 in co-Infected HIV-HCV [Phase 4]
Clinical trial update evaluating 24-week vs 48-week treatment durations for chronic hepatitis C genotypes 2 or 3 in people co-infected with …
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CLINICAL_TRIALS trial_result · 2008-02-08Clinical Trial Update: Comparison of Plasma Drug Levels of Triomune 40 With Those of the Originator Products [Phase 4]
Phase 4 study comparing plasma drug levels of Triomune 40 with those of the originator products in HIV infection.
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CLINICAL_TRIALS trial_result · 2008-02-08Clinical Trial Update: Twins Study of Gene Therapy for HIV Infection [Phase 1]
Phase 1 clinical trial update from NHGRI on a gene therapy approach for HIV infection, involving a twins study. The study status is COMPLETE…
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FDA approval · 2008-02-01FDA Approved: EPIVIR — Supplemental Application (ViiV Healthcare Company)
FDA approved a supplemental application for Epivir (lamivudine) submitted by ViiV Healthcare Company.
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CLINICAL_TRIALS trial_result · 2008-01-29Clinical Trial Update: Study to Evaluate the Effectiveness of ABC+3TC +EFV in Once-Daily Regimens Versus KLT in Twice-Daily Regimens in Naive HIV Patients [Phase 3]
A Phase 3 trial comparing once-daily ABC+3TC+EFV versus twice-daily KLT in treatment-naive HIV patients has completed.
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CLINICAL_TRIALS trial_result · 2008-01-29Clinical Trial Update: The Effect of Valacyclovir on the Detection of HIV From Genital Herpes Lesions in HIV-Infected Patients [NA]
A clinical trial evaluating whether valacyclovir affects HIV detection from genital herpes lesions in HIV-infected patients has completed.
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CLINICAL_TRIALS trial_result · 2008-01-29Clinical Trial Update: Antiretroviral Treatment Simplification Study With Efavirenz + Abacavir + 3TC Once Daily [Phase 3]
Phase 3 trial evaluating simplification of HIV antiretroviral therapy to once-daily efavirenz + abacavir + lamivudine; study status is compl…
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CLINICAL_TRIALS trial_result · 2008-01-29Clinical Trial Update: Immuno-Virological Efficacy of Combination With Trizivir +Tenofovir in Multiresistant HIV Patients [Phase 4]
Phase 4 trial assessing the immunovirological efficacy of combining Trizivir with Tenofovir in multiresistant HIV patients; the study has be…
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CLINICAL_TRIALS research · 2008-01-29Clinical Trial Update: Computer Assisted Rx Education for HIV-Positives: CARE+ [NA]
A completed clinical trial evaluating a computer-assisted prescription education program (CARE+) for individuals with HIV infection and AIDS…
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CLINICAL_TRIALS trial_result · 2008-01-25Clinical Trial Update: Yoga for Treating People at Risk for Diabetes or With Both HIV and Depression [Phase 1]
A Phase 1 clinical trial evaluating yoga as an intervention for people at risk for diabetes or with HIV infection and depression has complet…
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FDA approval · 2008-01-18FDA Approved: ETRAVIRINE — Original Application (Patriot Pharmaceuticals)
Etravirine received FDA approval as an original drug application for the treatment of HIV-1 infection in treatment-experienced adults, to be…
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CLINICAL_TRIALS trial_result · 2008-01-17Clinical Trial Update: The Efficacy of the HIV/AIDS Symptom Management Manual [NA]
A completed clinical trial evaluated the efficacy of a HIV/AIDS symptom management manual.
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CLINICAL_TRIALS trial_result · 2008-01-16Clinical Trial Update: SPL7013 Gel - Male Tolerance Study [Phase 1]
Phase 1 male tolerance study of SPL7013 Gel for HIV infection has completed.
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CLINICAL_TRIALS trial_result · 2008-01-10Clinical Trial Update: A Study of Valacyclovir to Suppress HSV and HIV Shedding in Coinfected Persons [Phase 4]
This document notes the completion of a Phase 4 clinical trial evaluating valacyclovir to suppress herpes simplex virus shedding and HIV she…
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CLINICAL_TRIALS trial_result · 2008-01-04Clinical Trial Update: Study of KP-1461 for the Treatment of HIV Positive Patients Who Have Failed Multiple HAART Regimens [Phase 1]
Phase 1 clinical trial update for KP-1461 in HIV-infected patients who have failed multiple HAART regimens; the study has completed.